George Perry

发表

MSDC-0160 and MSDC-0602 Binding with Human Mitochondrial Pyruvate Carrier (MPC) 1 and 2 Heterodimer: PPARγ Activating and Sparing TZDs as Therapeutics

Clyde F. Phelix, Greg Villareal, Allen K. Bourdon, 2017, Int. J. Knowl. Discov. Bioinform..

Transcriptome-To-Metabolome™ Biosimulation Reveals Human Hippocampal Hypometabolism with Age and Alzheimer's Disease

Clyde F. Phelix, Greg Villareal, Richard G. LeBaron, 2011, Int. J. Knowl. Discov. Bioinform..

Recent Advances in Medicinal Chemistry

Fabio Polticelli, Ann Nowé, Hendrik Fuchs, 2017 .

Low Dose Pioglitazone Attenuates Oxidative Damage in Early Alzheimer's Disease by Binding mitoNEET: Transcriptome-To-Reactome™ Biosimulation of Neurons

Clyde F. Phelix, Greg Villareal, Richard G. LeBaron, 2015, Int. J. Knowl. Discov. Bioinform..

In Vivo and In Silico Evidence: Hippocampal Cholesterol Metabolism Decreases with Aging and Increases with Alzheimers Disease -- Modeling Brain Aging and Disease

Clyde F. Phelix, Greg Villareal, Richard G. LeBaron, 2011, 2011 IEEE 11th International Conference on Data Mining Workshops.

Blue Ridge Community and Technical College Board of Governors Meeting

Craig Miller, Richard Snyder, George Perry, 2013 .

Precision pharmacology for Alzheimer's disease.

Norbert Benda, Simone Lista, Filippo Baldacci, 2018, Pharmacological research.

Testing the two-hit hypothesis of Alzheimer disease: Cell cycle re-entry

George Perry, 2013 .

Recent Developments: Barrie School v. Patch: There Is No Duty for a Non-Breaching Party to Mitigate Damages When the Contract Contains a Valid Liquidated Damages Clause

George Perry, 2008 .

CloningÃ¢ÂÂs Promise

George Perry, Rasha Shammas, Elizabeth A. Perry, 2013 .

The Lengthening Wire

Leland L. Johnson, Rolla Edward Park, W. S. Baer, 1972 .

Alzheimer's and Parkinson's Disease Novel Therapeutic Target: The Mitochondrial Pyruvate Carrier - Ligand Docking to Screen Natural Compounds Related to Classic Inhibitors

Clyde F. Phelix, Greg Villareal, Allen K. Bourdon, 2017, Int. J. Knowl. Discov. Bioinform..

Phytodiversity Assessment in Abandoned Solid Waste Dumpsites in Port Harcourt, Nigeria

George Perry, Angélica Rodríguez Dorantes, Gabriela Civeira, 2014 .

Oxidative stress in diabetes and Alzheimer's disease.

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2009, Journal of Alzheimer's disease : JAD.

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

George Perry, Paula I. Moreira, Xiongwei Zhu, 2009 .

Increased p27, an essential component of cell cycle control, in Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2003, Aging cell.

P38 activation mediates amyloid-beta cytotoxicity.

Hyoung-Gon Lee, George Perry, Xiongwei Zhu, 2005, Neurochemical research.

The neuroprotective activities of melatonin against the Alzheimer β‐protein are not mediated by melatonin membrane receptors

George Perry, Burkhard Poeggeler, M. Dubocovich, 2002, Journal of pineal research.

Differential Network Analyses of Alzheimer's Disease Identify Early Events in Alzheimer's Disease Pathology

David M. Rocke, Monika Ray, George Perry, 2014, International journal of Alzheimer's disease.

Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease

George Perry, Jesús Avila, J. Ávila, 2017, Oxidative medicine and cellular longevity.

Current hypotheses and research milestones in Alzheimer's disease

George Perry, G. Perry, R. Maccioni, 2009 .

Redox-active iron mediates amyloid-β toxicity

Ashley I. Bush, George Perry, Xiongwei Zhu, 2001 .

Transgenic Mouse Models of Alzheimer’s Disease: Behavioral Testing and Considerations

George Perry, Hyoung-Gon Lee, G. Casadesus, 2009 .

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta.

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2009, Journal of Alzheimer's disease : JAD.

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2009, The Journal of Neuroscience.

Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-β(1–40) and zinc(II)-bound amyloid-β(1–42) with dynamics

George Perry, Orkid Coskuner, Olivia Wise-Scira, 2012, JBIC Journal of Biological Inorganic Chemistry.

MAPKs are differentially modulated in arctic ground squirrels during hibernation

George Perry, Xiongwei Zhu, G. Perry, 2005, Journal of neuroscience research.

Signaling effect of amyloid-β42 on the processing of AβPP

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2010, Experimental Neurology.

Oxidative Stress and Neurodegeneration

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2005, Annals of the New York Academy of Sciences.

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2010, Redox report : communications in free radical research.

Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers

Shin J. Oh, George Perry, Jan Six, 1993, Brain Research.

Commentary: “Ceramide and cholesterol: Possible connections between normal aging of the brain and Alzheimer’s disease. Just hypotheses or molecular pathways to be identified?” By Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli

George Perry, G. Casadesus, Mark A. Smith, 2005, Alzheimer's & Dementia.

Overexpression of GRK2 in alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions

George Perry, Gjumrakch Aliev, M. Obrenovich, 2006, Neurotoxicity Research.

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology.

George Perry, Xiongwei Zhu, Cristina Carvalho, 2010, Biochimica et biophysica acta.

Prion disease and Alzheimer's disease: pathogenic overlap.

George Perry, R. Castellani, Mark A. Smith, 2004, Acta neurobiologiae experimentalis.

Gender Differences in Alzheimer Disease: The Role of Luteinizing Hormone in Disease Pathogenesis

George Perry, G. Casadesus, Mark A. Smith, 2005, Alzheimer disease and associated disorders.

The complexities of the pathology-pathogenesis relationship in Alzheimer disease.

George Perry, G. Perry, R. Castellani, 2014, Biochemical pharmacology.

Imaging the Alzheimer brain.

Norbert Schuff, Clifford R Jack, Ahmad Salehi, 2011, Journal of Alzheimer's disease : JAD.

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

John L Cleveland, Masaaki Komatsu, Katsuhiko Kitamoto, 2008, Autophagy.

Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation.

George Perry, Xiongwei Zhu, Gjumrakch Aliev, 2003, The American journal of pathology.

Leptin: a novel therapeutic strategy for Alzheimer's disease.

George Perry, Xiongwei Zhu, Steven J. Greco, 2009, Journal of Alzheimer's disease : JAD.

Senile plaque composition and posttranslational modification of amyloid-β peptide and associated proteins

George Perry, R. Martins, Mark A. Smith, 2002, Peptides.

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment.

George Perry, Xiongwei Zhu, Xinglong Wang, 2010, Journal of Alzheimer's disease : JAD.

Activation of p38 Kinase Links Tau Phosphorylation, Oxidative Stress, and Cell Cycle‐Related Events in Alzheimer Disease

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2000 .

Mathematical modeling of microtubule dynamics: Insights into physiology and disease

George Perry, Gavin A. Buxton, Mark A. Smith, 2010, Progress in Neurobiology.

Indices of Metabolic Dysfunction and Oxidative Stress

George Perry, Paula I. Moreira, G. Casadesus, 2007, Neurochemical Research.

Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2010, International journal of clinical and experimental pathology.

Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

Joseph S. Beckman, George Perry, Lawrence M. Sayre, 1997, The Journal of Neuroscience.

Physiological regulation of tau phosphorylation during hibernation

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2008, Journal of neurochemistry.

Antioxidant protection and neurodegenerative disease: The role of amyloid-β and tau

George Perry, Hyoung-Gon Lee, R. Castellani, 2006 .

Microbes and Alzheimer's Disease

Hugo Lövheim, Douglas B. Kell, Elaine L. Bearer, 2017 .

The Role of Mitogen-Activated Protein Kinase Pathways in Alzheimer’s Disease

George Perry, Xiongwei Zhu, G. Perry, 2002, Neurosignals.

Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2012, Journal of Alzheimer's disease : JAD.

Mitochondrial abnormalities in Alzheimer disease

Robert B. Petersen, George Perry, Shun Shimohama, 2000, Neurobiology of Aging.

Evidence for the role of luteinizing hormone in Alzheimer disease.

George Perry, G. Casadesus, Mark A. Smith, 2007, Endocrine, metabolic & immune disorders drug targets.

Role of the antioxidant ascorbate in hibernation and warming from hibernation.

George Perry, M. Rice, M. Smith, 2002, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology

George Perry, R. Martins, R. Castellani, 2002, Journal of neuroscience research.

Differential Regulation of Glutamate Receptors in Alzheimer’s Disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2002, Neurosignals.

Evidence that the β-Amyloid Plaques of Alzheimer's Disease Represent the Redox-silencing and Entombment of Aβ by Zinc*

Xudong Huang, George Perry, Craig S. Atwood, 2000, The Journal of Biological Chemistry.

Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency.

George Perry, E. Paley, O. Sokolova, 2013, Current Alzheimer research.

Amyloid-β peptide structure in aqueous solution varies with fragment size.

George Perry, Orkid Coskuner, Liang Xu, 2011, The Journal of chemical physics.

Nanoparticle and other metal chelation therapeutics in Alzheimer disease.

George Perry, Xiongwei Zhu, Ping Men, 2005, Biochimica et biophysica acta.

Alzheimer disease, the two-hit hypothesis: an update.

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2007, Biochimica et biophysica acta.

Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease.

Charles Thompson, George Perry, Amedeo D'Angiulli, 2015, Environmental research.

Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease

George Perry, Xiongwei Zhu, Xiongwei Zhu, 2008, Molecular Neurodegeneration.

RNA Oxidation Is a Prominent Feature of Vulnerable Neurons in Alzheimer’s Disease

George Perry, Shigeru Chiba, A. Nunomura, 1999, The Journal of Neuroscience.

Oxidative stress signalling in Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2004, Brain Research.

Chronic Effects of Mild Neurotrauma: Putting the Cart Before the Horse?

George Perry, Grant L Iverson, R. Castellani, 2015, Journal of neuropathology and experimental neurology.

Free radical damage, iron, and Alzheimer's disease

George Perry, Mark A. Smith, George Perry, 1995, Journal of the Neurological Sciences.

The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease

George Perry, Xiongwei Zhu, Ling Zheng, 2009, Journal of neurochemistry.

Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice.

George Perry, G. Casadesus, Mark A. Smith, 2006, Biochimica et biophysica acta.

Oxidative stress and neurotoxicity.

George Perry, Mark A. Smith, L. Sayre, 2008, Chemical research in toxicology.

Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

George Perry, Paula I. Moreira, Xiongwei Zhu, 2011, Ageing Research Reviews.

Systemic Increase of Oxidative Nucleic Acid Damage in Parkinson's Disease and Multiple System Atrophy

Yasuto Itoyama, George Perry, Atsushi Takeda, 2002, Neurobiology of Disease.

Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus

Uwe Karsten, George Perry, M. Kasper, 1987, Virchows Archiv A.

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence.

George Perry, Jian Dong, Mark A. Smith, 2003, Biochemistry.

Glycogen Synthase Kinase 3: A Point of Integration in Alzheimer's Disease and a Therapeutic Target?

George Perry, Paula I. Moreira, Xiongwei Zhu, 2012, International journal of Alzheimer's disease.

Role of mitochondrial dysfunction in Alzheimer's disease

George Perry, Gjumrakch Aliev, Atsushi Takeda, 2002, Journal of neuroscience research.

Microbes and Alzheimer's Disease.

Hugo Lövheim, Douglas B Kell, George Perry, 2016, Journal of Alzheimer's disease : JAD.

Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

Koji Abe, Mikio Shoji, George Perry, 2003, Journal of neurochemistry.

Distribution, levels, and activation of MEK1 in Alzheimer's disease

George Perry, Xiongwei Zhu, Hyoung-Gon Lee, 2003, Journal of neurochemistry.