Thomas B. Kepler

发表

A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays

Feng Feng, Ana Paula Sales, Thomas B. Kepler, 2011, Bioinform..

A Model of Large-Scale proteome Evolution

Ricard V. Solé, Thomas B. Kepler, Romualdo Pastor-Satorras, 2002, Adv. Complex Syst..

Statistical analysis of cellular aggregates in immunofluorescence histology

Thomas B. Kepler, Chunlin Ji, Shelley Stewart, 2009 .

HLA and HIV Infection Progression: Application of the Minimum Description Length Principle to Statistical Genetics

Thomas B. Kepler, Peter T. Hraber, Bette T. Korber, 2005, ISBMDA.

Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach

Jun Lu, Thomas B. Kepler, John K. Tomfohr, 2005, BMC Bioinformatics.

Flow: Statistics, visualization and informatics for flow cytometry

Cliburn Chan, Jacob Frelinger, Thomas B. Kepler, 2008, Source Code for Biology and Medicine.

BIOINFORMATICS ORIGINAL PAPER Genetics and population analysis Statistical analysis of antigen receptor spectratype data

Min He, Thomas B. Kepler, John K. Tomfohr, 2022 .

SoDA2: a Hidden Markov Model approach for identification of immunoglobulin rearrangements

Thomas B. Kepler, Supriya Munshaw, T. Kepler, 2010, Bioinform..

Oscillating networks: modeling the pyloric circuit of the stomatogastric ganglion

Eve Marder, Thomas B. Kepler, L. F. Abbott, 1990, 1990 IJCNN International Joint Conference on Neural Networks.

SpA: Web-accessible Spectratype Analysis: Application to Investigate the Development of TCR Diversity in a Patient with Complete DiGeorge Syndrome

Min He, Thomas B. Kepler, Blythe H. Devlin, 2006, BIOCOMP.

SpA: web-accessible spectratype analysis: data management, statistical analysis and visualization

Min He, Thomas B. Kepler, John K. Tomfohr, 2005, Bioinform..

The Dynamics of T-Cell Receptor Repertoire Diversity Following Thymus Transplantation for DiGeorge Anomaly

Thomas B. Kepler, Stanca M. Ciupe, Blythe H. Devlin, 2009, PLoS Comput. Biol..

Order Reduction for Dynamical Systems Describing the Behavior of Complex Neurons

Eve Marder, Thomas B. Kepler, L. F. Abbott, 1990, NIPS.

Reduction of conductance-based neuron models

Eve Marder, Thomas B. Kepler, L. F. Abbott, 1992, Biological Cybernetics.

A Bayesian approach for estimating calibration curves and unknown concentrations in immunoassays

Feng Feng, Ana Paula Sales, Thomas B. Kepler, 2012, Bioinform..

Mixtures of Gaussian wells: Theory, computation, and application

Thomas B. Kepler, Ioanna Manolopoulou, Daniel M. Merl, 2012, Comput. Stat. Data Anal..

SoDA: implementation of a 3D alignment algorithm for inference of antigen receptor recombinations

Thomas B. Kepler, Lindsay G. Cowell, Joseph M. Volpe, 2006, Bioinform..

Improving peptide-MHC class I binding prediction for unbalanced datasets

Ana Paula Sales, Thomas B. Kepler, Georgia D. Tomaras, 2008, BMC Bioinformatics.

Pathway level analysis of gene expression using singular value decomposition

Jun Lu, Thomas B. Kepler, John K. Tomfohr, 2005, BMC Bioinformatics.

The Multiscale Systems Immunology project: software for cell-based immunological simulation

Cliburn Chan, Feng Feng, Thomas B. Kepler, 2008, Source Code for Biology and Medicine.

Spike initiation and propagation on axons with slow inward currents

Eve Marder, Thomas B. Kepler, E. Marder, 2004, Biological Cybernetics.

The Nucleotide-Replacement Spectrum Under Somatic Hypermutation Exhibits Microsequence Dependence That Is Strand-Symmetric and Distinct from That Under Germline Mutation1

Thomas B. Kepler, T. Kepler, Lindsay G. Cowell, 2000, The Journal of Immunology.

Physiological Insights from Cellular and Network Models of the Stomatogastric Nervous System of Lobsters and Crabs

Eve Marder, Thomas B. Kepler, Jorge Golowasch, 1993 .

Bayesian Spatio-Dynamic Modeling in Cell Motility Studies: Learning Nonlinear Taxic Fields Guiding the Immune Response

Michael D. Cahalan, Thomas B. Kepler, Ioanna Manolopoulou, 2012 .

Diversification of Ig Superfamily Genes in an Invertebrate

Thomas B. Kepler, Eric S. Loker, T. Kepler, 2004, Science.

Chaos in a neural network circuit

Thomas B. Kepler, L. F. Abbott, Robert B. Meyer, 1990 .

Microsimulation of Inducible Reorganization in Immunity

Thomas B. Kepler, T. Kepler, 2006 .

Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes

Thomas B. Kepler, Donna Neuberg, Frederick W. Alt, 2015, Cell.

Belowground factors mediating changes in methane consumption in a forest soil under elevated CO2

Thomas B. Kepler, Dianne Ahmann, T. Kepler, 2002 .

A two-tiered model for simulating the ecological and evolutionary dynamics of rapidly evolving viruses, with an application to influenza

Thomas B. Kepler, Katia Koelle, Priya Khatri, 2010, Journal of The Royal Society Interface.

Modification of Oscillator Function by Electrical Coupling to Nonoscillatory Neurons

Eve Marder, Thomas B. Kepler, Scott L. Hooper, 1992 .

Domains of attraction in neural networks

Thomas B. Kepler, L. F. Abbott, L. Abbott, 1988 .

Optimal learning in neural network memories

Thomas B. Kepler, L. F. Abbott, 1989 .

Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production

Thomas B. Kepler, Min Zhu, Douglas A. Lauffenburger, 2015, Obesity.

Universality in the space of interactions for network models

Thomas B. Kepler, L. F. Abbott, L. Abbott, 1989 .

Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains

Thomas B. Kepler, Barton F. Haynes, Hua-Xin Liao, 2014, Proceedings of the National Academy of Sciences.

The Targeting of Somatic Hypermutation Closely Resembles That of Meiotic Mutation1

Thomas B. Kepler, Lindsay G. Cowell, Mihaela Oprea, 2001, The Journal of Immunology.

Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies

Feng Gao, Tongqing Zhou, Thomas B. Kepler, 2014, Cell.

Interdependence of N Nucleotide Addition and Recombination Site Choice in V(D)J Rearrangement

Thomas B. Kepler, T. Kepler, S. Clarke, 1996, The Journal of Immunology.

Open Source Research — the Power of Us

Thomas B. Kepler, Stephen M. Maurer, Matthew H. Todd, 2006 .

Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation

Thomas B. Kepler, Christopher W. Woods, S. Munir Alam, 2014, Front. Immunol..

Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

Thomas B. Kepler, Huafeng Xu, Surender Khurana, 2012, Proceedings of the National Academy of Sciences.

Unselected Mutations in the Human Immunodeficiency Virus Type 1 Genome Are Mostly Nonsynonymous and Often Deleterious

Thomas B. Kepler, Feng Gao, T. Kepler, 2004, Journal of Virology.

Computational Implications of a Serotonin-Sensitive Region of Axonal Membrane On a Dual Function Motor Neuron

Eve Marder, Thomas B. Kepler, L. F. Abbott, 1993 .

Enhanced Evolvability in Immunoglobulin V Genes Under Somatic Hypermutation

Thomas B. Kepler, Lindsay G. Cowell, T. Kepler, 1999, Journal of Molecular Evolution.

β Cell-Specific CD4+ T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct1

Thomas B. Kepler, Bo Wang, T. Kepler, 2009, The Journal of Immunology.

Application of cDNA Microarray Technology to In Vitro Toxicology and the Selection of Genes for a Real-Time RT-PCR-Based Screen for Oxidative Stress in Hep-G2 Cells

Thomas B. Kepler, Steven P. Anderson, Kevin T. Morgan, 2002, Toxicologic pathology.