A. Kenyon

Evaluation of the use of UPLC-TOFMS with simultaneous [14C]-radioflow detection for drug metabolite profiling: application to propranolol metabolites in rat urine.

I. Wilson, T. Athersuch, R. Sison, 2008, Journal of pharmaceutical and biomedical analysis.

The disposition and metabolism of zibotentan (ZD4054): an oral-specific endothelin A receptor antagonist in mice, rats and dogs

H. Tomkinson, A. Kenyon, J.A. Clarkson-Jones, 2011, Xenobiotica; the fate of foreign compounds in biological systems.

Disposition and metabolism of the specific endothelin A receptor antagonist zibotentan (ZD4054) in healthy volunteers

E. Lenz, J. Kemp, S. Oliver, 2012, Xenobiotica; the fate of foreign compounds in biological systems.

The metabolism of [14C]-zibotentan (ZD4054) in rat, dog and human, the loss of the radiolabel and the identification of an anomalous peak, derived from the animal feed.

E. Lenz, H. Tomkinson, D. Temesi, 2011, Journal of pharmaceutical and biomedical analysis.

724 POSTER Metabolism of [14C]-ZD4054 in healthy volunteers

E. Lenz, J. Kemp, S. Oliver, 2007 .