H. Brewer

发表

PHENOTYPE STUDY OF APOLIPOPROTEIN E ISOFORMS IN HYPERLIPOPROTEINAEMIC PATIENTS

R. Gregg, H. Brewer, E. Schaefer, 1982, The Lancet.

In vitro activation of the enzymic activity of hepatic lipase by apoA‐II

H. Brewer, E. Schaefer, J. C. Osborne, 1981, FEBS letters.

Evaluation of urinary cells in acid cholesteryl ester hydrolase deficiency

H. Brewer, J. Hoeg, P. Kwiterovich, 1986, Clinical genetics.

Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: a randomized controlled trial.

Ming-Dauh Wang, M. Shao, J. Kastelein, 2011, JAMA.

The impact of proprotein convertase subtilisin-kexin type 9 serine protease inhibitors on lipid levels and outcomes in patients with primary hypercholesterolaemia: a network meta-analysis.

H. Brewer, R. Torguson, R. Waksman, 2016, European heart journal.

ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice.

H. Brewer, R. Shamburek, A. Remaley, 2001, The Journal of clinical investigation.

The Farnesoid X-receptor Is an Essential Regulator of Cholesterol Homeostasis*

Grace Guo, H. Brewer, F. Gonzalez, 2003, The Journal of Biological Chemistry.

The ABCA1 transporter functions on the basolateral surface of hepatocytes.

H. Brewer, A. Remaley, C. Combs, 2002, Biochemical and biophysical research communications.

Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively.

A. Pandya, A. Brooks-Wilson, H. Brewer, 2001, American journal of human genetics.

PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

M. Jaye, H. Brewer, A. Remaley, 2001, Nature Medicine.

Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines.

S. Grundy, J. Cleeman, Sidney C. Smith, 2004, Arteriosclerosis, thrombosis, and vascular biology.

A first-in-man, randomized, placebo-controlled study to evaluate the safety and feasibility of autologous delipidated high-density lipoprotein plasma infusions in patients with acute coronary syndrome.

P. Fitzgerald, N. Weissman, H. Brewer, 2010, Journal of the American College of Cardiology.

Apolipoprotein specificity for lipid efflux by the human ABCAI transporter.

H. Brewer, A. Remaley, T. Eggerman, 2001, Biochemical and biophysical research communications.

Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport.

Zahi A Fayad, Valentin Fuster, V. Fuster, 2012, Circulation.

Cardiovascular features of homozygous familial hypercholesterolemia: analysis of 16 patients.

B. McManus, W. Roberts, R. Gregg, 1984, The American journal of cardiology.

Activation of human post heparin lipoprotein lipase by apolipoprotein H (beta 2-glycoprotein I).

H. Brewer, E. Schaefer, Y. Nakaya, 1980, Biochemical and biophysical research communications.

Dysfunctional HDL and atherosclerotic cardiovascular disease

P. Barter, A. Tall, H. Brewer, 2016, Nature Reviews Cardiology.

Cholesteryl Ester Transfer Protein Corrects Dysfunctional High Density Lipoproteins and Reduces Aortic Atherosclerosis in Lecithin Cholesterol Acyltransferase Transgenic Mice*

R. F. Hoyt, H. Brewer, R. Shamburek, 1999, The Journal of Biological Chemistry.

Effectiveness of mevinolin on plasma lipoprotein concentrations in type II hyperlipoproteinemia.

K. Bailey, R. Gregg, J. Hoeg, 1986, The American journal of cardiology.

Evacetrapib alone or in combination with statins lowers lipoprotein(a) and total and small LDL particle concentrations in mildly hypercholesterolemic patients.

H. Brewer, S. Nissen, K. Krueger, 2016, Journal of clinical lipidology.

Clinical review: The evolving role of HDL in the treatment of high-risk patients with cardiovascular disease.

H. Brewer, H. Brewer, 2011, The Journal of clinical endocrinology and metabolism.

Human apolipoprotein A‐II: complete nucleic acid sequence of preproapoA‐II

K. Lackner, S. Law, H. Brewer, 1984, FEBS letters.

ApoA-I Induction as a Potential Cardioprotective Strategy: Rationale for the SUSTAIN and ASSURE Studies

P. Barter, J. Kastelein, C. Ballantyne, 2012, Cardiovascular Drugs and Therapy.

Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study

Habib Samady, Francesco Prati, Eric Powers, 2019, The Lancet.

Impact of low high-density lipoproteins on in-hospital events and one-year clinical outcomes in patients with non-ST-elevation myocardial infarction acute coronary syndrome treated with drug-eluting stent implantation.

H. Brewer, K. Kent, A. Pichard, 2006, The American journal of cardiology.

The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver Published, JLR Papers in Press, July 16, 2005. DOI 10.1194/jlr.M500080-JLR200

H. Brewer, S. Sabol, S. Santamarina-Fojo, 2005, Journal of Lipid Research.

Lipoproteins as Biomarkers and Therapeutic Targets in the Setting of Acute Coronary Syndrome

D. Rader, H. Brewer, R. Rosenson, 2014, Circulation research.

The effects of mevinolin and neomycin alone and in combination on plasma lipid and lipoprotein concentrations in type II hyperlipoproteinemia.

K. Bailey, H. Brewer, J. Hoeg, 1986, Atherosclerosis.

Levels of lipoprotein Lp(a) decline with neomycin and niacin treatment.

H. Brewer, J. Hoeg, N. Papadopoulos, 1985, Atherosclerosis.

Study of ABCA1 function in transgenic mice.

H. Brewer, L. Freeman, S. Santamarina-Fojo, 2003, Arteriosclerosis, thrombosis, and vascular biology.

HDL metabolism and the role of HDL in the treatment of high-risk patients with cardiovascular disease

H. Brewer, H. Bryan Brewer, H. Brewer, 2007, Current cardiology reports.

The ABCA1 Transporter Modulates Late Endocytic Trafficking

H. Brewer, A. Remaley, C. Combs, 2004, Journal of Biological Chemistry.

Lecithin-cholesterol acyltransferase: role in lipoprotein metabolism, reverse cholesterol transport and atherosclerosis.

J. Hoeg, G. Lambert, S. Santamarina-Fojo, 2000, Current opinion in lipidology.

Studies on the mechanism of hypertriglyceridemia in Tangier disease. Determination of plasma lipolytic activities, k1 values and apolipoprotein composition of the major lipoprotein density classes.

R. Gregg, C. S. Wang, P. Alaupovic, 1987, Biochimica et biophysica acta.

Plasma Phospholipid Transfer Protein

H. Brewer, R. Shamburek, B. Föger, 1997, The Journal of Biological Chemistry.

High-density lipoproteins: a new potential therapeutic target for the prevention of cardiovascular disease.

H. Brewer, H. Brewer, H. Bryan Brewer, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Analysis of the mixed association between human apolipoproteins A-I and A-II in aqueous solution.

H. Brewer, J. C. Osborne, G. M. Powell, 1980, Biochimica et biophysica acta.

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial

D. Rader, P. Barter, J. Kastelein, 2015, The Lancet.

Translation of High-Density Lipoprotein Function Into Clinical Practice: Current Prospects and Future Challenges

P. Barter, A. Tall, H. Brewer, 2013, Circulation.

Cellular Localization and Trafficking of the Human ABCA1 Transporter* 210

A. Remaley, S. Demosky, J. Stonik, 2001, The Journal of Biological Chemistry.

The Ligand-binding Function of Hepatic Lipase Modulates the Development of Atherosclerosis in Transgenic Mice*

H. Brewer, R. Shamburek, B. Paigen, 2004, Journal of Biological Chemistry.

High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithinchoesteryl acyltransferase

R. F. Hoyt, H. Brewer, R. Shamburek, 1997, Nature Medicine.

Targeted Disruption of the Mouse Lecithin:Cholesterol Acyltransferase (LCAT) Gene

R. F. Hoyt, H. Brewer, C. Koch, 1997, The Journal of Biological Chemistry.

Effect of the BET Protein Inhibitor, RVX-208, on Progression of Coronary Atherosclerosis: Results of the Phase 2b, Randomized, Double-Blind, Multicenter, ASSURE Trial

P. Barter, J. Kastelein, C. Ballantyne, 2016, American Journal of Cardiovascular Drugs.

Hypertriglyceridemia: changes in the plasma lipoproteins associated with an increased risk of cardiovascular disease.

H. Brewer, H. Brewer, 1999, The American journal of cardiology.

A mutation in apolipoprotein A-I in the Iowa type of familial amyloidotic polyneuropathy.

R. Gregg, M. Benson, W. Nichols, 1990, Genomics.

Benefit-risk assessment of Rosuvastatin 10 to 40 milligrams.

H. Brewer, H. Brewer, 2003, The American journal of cardiology.

Novel Therapies Focused on the High-Density Lipoprotein Particle

J. Kastelein, J. Kastelein, G. Hovingh, 2014, Circulation research.

Lecithin:Cholesterol Acyltransferase Overexpression Generates Hyperalpha-lipoproteinemia and a Nonatherogenic Lipoprotein Pattern in Transgenic Rabbits (*)

R. F. Hoyt, J. Hoeg, A. Bérard, 1996, The Journal of Biological Chemistry.

Lipids, Apolipoproteins and Lipoproteins

D. Rader, H. Brewer, H. Brewer, 1994 .

Discrimination between RRR- and all-racemic-alpha-tocopherols labeled with deuterium by patients with abetalipoproteinemia.

D. Rader, H. Brewer, M. Traber, 1994, Atherosclerosis.

New insights into the role of the adenosine triphosphate-binding cassette transporters in high-density lipoprotein metabolism and reverse cholesterol transport.

H. Brewer, H Bryan Brewer, Silvia Santamarina-Fojo, 2003, The American journal of cardiology.

Analysis of Glomerulosclerosis and Atherosclerosis in Lecithin Cholesterol Acyltransferase-deficient Mice*

J. Brady, G. Striker, H. Brewer, 2001, The Journal of Biological Chemistry.

Cholesterol ester transfer protein inhibition by TA-8995 in patients with mild dyslipidaemia (TULIP): a randomised, double-blind, placebo-controlled phase 2 trial

D. Rader, P. Barter, J. Kastelein, 2015, The Lancet.

SOLUTION PROPERTIES OF THE PLASMA APOLIPOPROTEINS

J. C. Osborne, H. Brewer, 1980, Annals of the New York Academy of Sciences.