P. M. Gore

发表

Optimization of Orally Bioavailable PI3K delta Inhibitors and Identification of Vps34 as a Key Selectivity Target.

P. Grandi, Birgit Dümpelfeld, M. Bantscheff, 2020 .

Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a key off-target activity.

P. Grandi, Christina Rau, M. Bantscheff, 2019, Journal of medicinal chemistry.

Mimics of the sialyl Lewis X tetrasaccharide. Replacement of the N-acetylglucosamine sugar with simple C2-symmetric 1,2-diols.

D. Holmes, M. Bamford, R. Priest, 1996, Bioorganic & medicinal chemistry.

The discovery of quinoline based single-ligand human H1 and H3 receptor antagonists.

S. Hodgson, D. Holmes, P. Procopiou, 2016, Bioorganic & medicinal chemistry letters.

The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis.

Kenneth L. Clark, Duncan S. Holmes, Michael Kranz, 2011, Journal of medicinal chemistry.

New spiropiperidines as potent and selective non-peptide tachykinin NK2 receptor antagonists.

A. Mcelroy, N. Taylor, J. Pritchard, 1995, Journal of medicinal chemistry.

Identification of selective 8-(piperidin-4-yloxy)quinoline sulfone and sulfonamide histamine H1 receptor antagonists for use in allergic rhinitis.

K. Clark, S. Hodgson, D. Holmes, 2017, Bioorganic & medicinal chemistry letters.

Design of Phthalazinone Amide Histamine H1 Receptor Antagonists for Use in Rhinitis.

K. Clark, S. Hodgson, D. Holmes, 2017, ACS medicinal chemistry letters.

Synthesis and pharmacological investigation of azaphthalazinone human histamine H(1) receptor antagonists.

C. Browning, S. Lynn, P. Procopiou, 2012, Bioorganic & medicinal chemistry.

Intermediates for the synthesis of linear chains of 1,2:4,5-fused cyclohexa-1,4-diene rings and beltenes by repeated Diels–Alder reactions

R. Alder, M. H. Perry, Nicholas M. Hext, 1994 .

GR159897 and related analogues as highly potent, orally active non-peptide neurokinin NK2 receptor antagonists.

Paul W Smith, A. Mcelroy, J. Pritchard, 1994 .

Divergent approach to imino sugar C-glycosides using imino glycals: application to the stereocontrolled synthesis of (+)-deoxoprosophylline.

A. Slawin, M. Shipman, P. Dransfield, 2002, Chemical communications.