Paul A Clemons

发表

An Economic Framework to Prioritize Confirmatory Tests after a High-Throughput Screen

S Joshua Swamidass, Joshua A Bittker, Nicole E Bodycombe, 2010, Journal of biomolecular screening.

Master data management: getting your house in order.

Nicole E Bodycombe, Paul A Clemons, Kathleen Petri Seiler, 2011, Combinatorial chemistry & high throughput screening.

Computational Analyses Connect Small-Molecule Sensitivity to Cellular Features Using Large Panels of Cancer Cell Lines.

Paul A Clemons, Matthew G Rees, Brinton Seashore-Ludlow, 2018, Methods in molecular biology.

Data-analysis strategies for image-based cell profiling

Lassi Paavolainen, Peng Qiu, Anne E Carpenter, 2017, Nature Methods.

High-throughput Identification of Phage-derived Imaging Agents

Paul A Clemons, Ralph Weissleder, Kimberly A Kelly, 2006, Molecular imaging.

A dataset of images and morphological profiles of 30 000 small-molecule treatments using the Cell Painting assay

Anne E Carpenter, Joshua A Bittker, Nicole E Bodycombe, 2017, GigaScience.

Chemical Genomics

Paul A Clemons, Stephen J Haggarty, Bridget K Wagner, 2004, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.

Using ChemBank to Probe Chemical Biology

Paul A Clemons, Heidi Kuehn, Kathleen Petri Seiler, 2008, Current protocols in bioinformatics.

An Overview of the Challenges in Designing, Integrating, and Delivering BARD

Tudor I. Oprea, Noel Southall, Stephan C Schürer, 2014, Journal of biomolecular screening.

The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

Paul A Clemons, Aravind Subramanian, Steven A Carr, 2006, Science.

Knowledge from Small-Molecule Screening and Profiling Data

Paul A Clemons, Darren V S Green, P. Clemons, 2014, Journal of biomolecular screening.

Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space.

Paul A Clemons, Stuart L Schreiber, Nick Patterson, 2004, Journal of the American Chemical Society.

Complex phenotypic assays in high-throughput screening.

Paul A Clemons, P. Clemons, 2004, Current opinion in chemical biology.

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.

Fatima Al-Shahrour, Anne E Carpenter, Benito Munoz, 2013, Nature chemical biology.

Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.

Paul A Clemons, Nevan J Krogan, Stuart L Schreiber, 2015, Cancer discovery.

Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.

Paul A Clemons, Stuart L Schreiber, Stephen J Haggarty, 2004, Combinatorial chemistry & high throughput screening.

The Biomedical Data Translator Program: Conception, Culture, and Community

Paul A Clemons, P. Clemons, 2018, Clinical and translational science.

Chemical genomic profiling of biological networks using graph theory and combinations of small molecule perturbations.

Paul A Clemons, Stuart L Schreiber, Stephen J Haggarty, 2003, Journal of the American Chemical Society.

A pipeline for ligand discovery using small-molecule microarrays.

Paul A Clemons, Angela N Koehler, P. Clemons, 2007, Current opinion in chemical biology.

Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery.

Paul A Clemons, Bridget K Wagner, P. Clemons, 2015, Trends in genetics : TIG.

Connecting synthetic chemistry decisions to cell and genome biology using small-molecule phenotypic profiling.

Paul A Clemons, Bridget K Wagner, P. Clemons, 2009, Current opinion in chemical biology.

A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors

Paul A Clemons, Andrea Califano, Daniel Kaemmerer, 2018, Nature Genetics.

Towards patient-based cancer therapeutics

Benito Munoz, Michelle Palmer, Paul A Clemons, 2010, Nature Biotechnology.

Identification of cancer cytotoxic modulators of PDE3A by predictive chemogenomics

Benito Munoz, Paul A Clemons, Aviad Tsherniak, 2015, Nature chemical biology.