William J. Jusko

发表

Circadian signatures in rat liver: from gene expression to pathways

Ioannis P. Androulakis, Siddharth Sukumaran, Meric A. Ovacik, 2010, BMC Bioinformatics.

Fourth-Generation Model for Corticosteroid Pharmacodynamics: A Model for Methylprednisolone Effects on Receptor/Gene-Mediated Glucocorticoid Receptor Down-Regulation and Tyrosine Aminotransferase Induction in Rat Liver

Richard R. Almon, Debra C. DuBois, William J. Jusko, 1998, Journal of Pharmacokinetics and Biopharmaceutics.

Methods of utilizing baseline values for indirect response models

William J. Jusko, Sukyung Woo, Dipti Pawaskar, 2009, Journal of Pharmacokinetics and Pharmacodynamics.

Foundations of Pharmacodynamic Systems Analysis

William J. Jusko, W. Jusko, 2016 .

Target-mediated drug disposition with drug–drug interaction, Part I: single drug case in alternative formulations

William J. Jusko, Gilbert Koch, Johannes Schropp, 2017, Journal of Pharmacokinetics and Pharmacodynamics.

Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat liver

Ioannis P. Androulakis, Tung T. Nguyen, Richard R. Almon, 2010, BMC Bioinformatics.

The PEPR GeneChip data warehouse, and implementation of a dynamic time series query tool (SGQT) with graphical interface

Eric P. Hoffman, Josephine Chen, Richard R. Almon, 2004, Nucleic Acids Res..

New journal cover

William J. Jusko, 2010, Journal of Pharmacokinetics and Pharmacodynamics.

REVIEWS Moving from Basic Toward Systems Pharmacodynamic Models

William J. Jusko, W. Jusko, 2013 .

Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regulatory structures

Ioannis P. Androulakis, Tung T. Nguyen, Richard R. Almon, 2010, BMC Bioinformatics.

Effect of diphenhydramine on prednisolone elimination kinetics

William J. Jusko, M L Rocci, Stanley J. Szefler, 1979 .

Current concepts in the pharmaceutical sciences: Dosage form design and bioavailability. Edited by JAMES SWARBRICK. Lea & Febiger, Philadelphia, Pa 19106, 1973. xi + 230 pp. 18 × 26 cm. Price $19.50

William J. Jusko, 1974 .

Assessment of non-linear combination effect terms for drug–drug interactions

William J. Jusko, Gilbert Koch, Johannes Schropp, 2016, Journal of Pharmacokinetics and Pharmacodynamics.

Development and Qualification of a Pharmacodynamic Model for the Pronounced Inoculum Effect of Ceftazidime against Pseudomonas aeruginosa

Neang S. Ly, Brian T. Tsuji, Alan Forrest, 2008, Antimicrobial Agents and Chemotherapy.

Mechanistic Modeling of the Effects of Glucocorticoids and Circadian Rhythms on Adipokine Expression

Siddharth Sukumaran, Richard R. Almon, Debra C. DuBois, 2011, Journal of Pharmacology and Experimental Therapeutics.

Receptor-Mediated Pharmacokinetic/Pharmacodynamic Model of Interferon-β 1a in Humans

Donald E. Mager, William J. Jusko, W. Jusko, 2002, Pharmaceutical Research.

Gene arrays and temporal patterns of drug response: corticosteroid effects on rat liver

Richard R. Almon, Debra C. DuBois, William J. Jusko, 2003, Functional & Integrative Genomics.

Convergence of direct and indirect pharmacodynamic response models

Hui C. Ko, William J. Jusko, W. Jusko, 1995, Journal of Pharmacokinetics and Biopharmaceutics.

Assessment of Pharmacologic Area Under the Curve When Baselines are Variable

Ioannis P. Androulakis, Jeremy D. Scheff, Richard R. Almon, 2011, Pharmaceutical Research.

Indirect Pharmacodynamic Models for Responses with Multicompartmental Distribution or Polyexponential Disposition

Wojciech Krzyzanski, William J. Jusko, W. Jusko, 2001, Journal of Pharmacokinetics and Pharmacodynamics.

Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology.

Siddharth Sukumaran, Richard R. Almon, Debra C. DuBois, 2010, Physiological genomics.

Quantitative and Systems Pharmacology in the Post-genomic Era : New Approaches to Discovering Drugs and Understanding Therapeutic

Ravi Iyengar, Darrell R. Abernethy, Paolo Vicini, 2011 .

Clinical pharmacokinetics of procainamide infusions in relation to acetylator phenotype

William J. Tilstone, William J. Jusko, W. Jusko, 1979, Journal of Pharmacokinetics and Biopharmaceutics.

Second generation model for prednisolone pharmacodynamics in the rat

William J. Jusko, W. Jusko, F. D. Boudinot, 1989, Journal of Pharmacokinetics and Biopharmaceutics.

Applications of minimal physiologically-based pharmacokinetic models

William J. Jusko, W. Jusko, Yanguang Cao, 2012, Journal of Pharmacokinetics and Pharmacodynamics.

Modeling Corticosteroid Effects in a Rat Model of Rheumatoid Arthritis I: Mechanistic Disease Progression Model for the Time Course of Collagen-Induced Arthritis in Lewis Rats

Richard R. Almon, Debra C. DuBois, William J. Jusko, 2008, Journal of Pharmacology and Experimental Therapeutics.

Assessment of Drug Interactions Relevant to Pharmacodynamic Indirect Response Models

Wojciech Krzyzanski, William J. Jusko, Justin C. Earp, 2004, Journal of Pharmacokinetics and Pharmacodynamics.

Third-generation model for corticosteroid pharmacodynamics: Roles of glucocorticoid receptor mRNA and tyrosine aminotransferase mRNA in rat liver

Richard R. Almon, Debra C. DuBois, William J. Jusko, 1995, Journal of Pharmacokinetics and Biopharmaceutics.

Modeling Disease Progression and Rosiglitazone Intervention in Type 2 Diabetic Goto-Kakizaki Rats

William J. Jusko, W. Jusko, Wei Gao, 2012, Journal of Pharmacology and Experimental Therapeutics.

Mathematical Modeling of Circadian Cortisol Concentrations Using Indirect Response Models: Comparison of Several Methods

Wojciech Krzyzanski, William J. Jusko, W. Jusko, 1999, Journal of Pharmacokinetics and Biopharmaceutics.

Mathematical Formalism and Characteristics of Four Basic Models of Indirect Pharmacodynamic Responses for Drug Infusions

Wojciech Krzyzanski, William J. Jusko, 2004, Journal of Pharmacokinetics and Biopharmaceutics.

Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids

Richard R. Almon, Debra C. DuBois, William J. Jusko, 2007, Journal of Pharmacokinetics and Pharmacodynamics.

Survey of monoclonal antibody disposition in man utilizing a minimal physiologically-based pharmacokinetic model

William J. Jusko, Yanguang Cao, 2014, Journal of Pharmacokinetics and Pharmacodynamics.

Pharmacodynamics and Pharmacogenomics of Diverse Receptor-Mediated Effects of Methylprednisolone in Rats Using Microarray Analysis

Shuzhong Zhang, Richard R. Almon, Debra C. DuBois, 2002, Journal of Pharmacokinetics and Pharmacodynamics.

Perspectives on the history and scientific contributions of Gerhard Levy

William J. Jusko, W. Jusko, H. Fung, 2015, Journal of Pharmacokinetics and Pharmacodynamics.

General Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, William J. Jusko, W. Jusko, 2001, Journal of Pharmacokinetics and Pharmacodynamics.

Dose-Dependence and Repeated-Dose Studies for Receptor/Gene-Mediated Pharmacodynamics of Methylprednisolone on Glucocorticoid Receptor Down-Regulation and Tyrosine Aminotransferase Induction in Rat Liver

Richard R. Almon, Debra C. DuBois, William J. Jusko, 1998, Journal of Pharmacokinetics and Biopharmaceutics.

Meta-Modeling of Methylprednisolone Effects on Glucose Regulation in Rats

Siddharth Sukumaran, Richard R. Almon, Debra C. DuBois, 2013, PloS one.

Across-Species Scaling of Monoclonal Antibody Pharmacokinetics Using a Minimal PBPK Model

William J. Jusko, W. Jusko, Jie Zhao, 2015, Pharmaceutical Research.

Receptor-mediated pharmacodynamics of prednisolone in the rat

William J. Jusko, W. Jusko, F. D. Boudinot, 1986, Journal of Pharmacokinetics and Biopharmaceutics.

Pharmacokinetic/Pharmacodynamic Modelling in Diabetes Mellitus

William J. Jusko, Cornelia B. Landersdorfer, W. Jusko, 2008, Clinical pharmacokinetics.

Quantitative Dynamic Models of Arthritis Progression in the Rat

Richard R. Almon, Debra C. DuBois, William J. Jusko, 2008, Pharmaceutical Research.

Incorporating target-mediated drug disposition in a minimal physiologically-based pharmacokinetic model for monoclonal antibodies

William J. Jusko, W. Jusko, Yanguang Cao, 2014, Journal of Pharmacokinetics and Pharmacodynamics.

A pharmacodynamic model for cell-cycle-specific chemotherapeutic agents

William J. Jusko, W. Jusko, 1973, Journal of Pharmacokinetics and Biopharmaceutics.

Berichten

William J. Jusko, Jerome J. Schentag, W. Jusko, 2005, Pharmaceutisch weekblad.

Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats

Wei Gao, Richard R. Almon, Debra C. DuBois, 2011, Journal of Pharmacokinetics and Pharmacodynamics.

Two-compartment basophil cell trafficking model for methylprednisolone pharmacodynamics

Daniel E. Salazar, William J. Jusko, W. Jusko, 1991, Journal of Pharmacokinetics and Biopharmaceutics.

Enhancement of Tissue Delivery and Receptor Occupancy of Methylprednisolone in Rats by a Liposomal Formulation

William J. Jusko, Robert M. Straubinger, N. Pyszczynski, 1993, Pharmaceutical Research.

Second-generation minimal physiologically-based pharmacokinetic model for monoclonal antibodies

William J. Jusko, Joseph P. Balthasar, Yanguang Cao, 2013, Journal of Pharmacokinetics and Pharmacodynamics.

Modeling Circadian Rhythms of Glucocorticoid Receptor and Glutamine Synthetase Expression in Rat Skeletal Muscle

Richard R. Almon, Debra C. DuBois, William J. Jusko, 2006, Pharmaceutical Research.