Ethan M. Earlie

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression

Ashley M. Laughney, M. Goldbaum, P. Mischel, 2021, Nature Communications.

Lineage-specific intolerance to oncogenic drivers restricts histological transformation

Ashley M. Laughney, H. Varmus, M. Hubisz, 2023, bioRxiv.

Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression

Ashley M. Laughney, J. Blenis, Noah Dephoure, 2022, Nature Communications.

Non-cell-autonomous cancer progression from chromosomal instability

Ashley M. Laughney, J. Reis-Filho, M. Hubisz, 2023, Nature.

Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation.

Ashley M. Laughney, Sven W. Meckelmann, S. Bakhoum, 2024, Nature cancer.