Auzon Steffy

(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.

Nanxin Li, Jennifer L. Harris, Jianwei Che, 2015, ACS medicinal chemistry letters.

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

W. Sellers, P. Schultz, Jennifer L. Harris, 2013, Proceedings of the National Academy of Sciences.

Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2

Sungjoon Kim, Nanxin Li, M. Warmuth, 2013, Journal of medicinal chemistry.

Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.

Sungjoon Kim, Nanxin Li, Christian C. Lee, 2016, Bioorganic & medicinal chemistry letters.

Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors.

Jennifer L. Harris, S. Kasibhatla, D. Han, 2016, ACS medicinal chemistry letters.

Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

V. Bafna, S. Milutinovic, Philip Hanoian, 2024, bioRxiv.