J. Darling

发表

Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake

S. Subramaniam, B. Chait, K. Wollenberg, 2021, eLife.

Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures

S. Subramaniam, M. Drew, J. Suryadi, 2020, IUCrJ.

Structure-activity analysis of human ghrelin O-acyltransferase reveals chemical determinants of ghrelin selectivity and acyl group recognition.

James L. Hougland, R. Gibbs, Feifei Zhao, 2015, Biochemistry.

Ghrelin Octanoylation Is Completely Stabilized in Biological Samples by Alkyl Fluorophosphonates.

James L. Hougland, A. Abizaid, Michelle A. Sieburg, 2016, Endocrinology.

A fluorescent peptide substrate facilitates investigation of ghrelin recognition and acylation by ghrelin O-acyltransferase.

James L. Hougland, Michelle A. Sieburg, J. E. Darling, 2013, Analytical biochemistry.

Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding after a Fast, and Adiposity in Mice

James L. Hougland, J. Zigman, A. Abizaid, 2015, Front. Endocrinol..

A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups.

James L. Hougland, R. Gibbs, Feifei Zhao, 2015, Bioorganic & medicinal chemistry letters.

1.8 Å resolution structure of β-galactosidase with a 200 kV CRYO ARM electron microscope

S. Subramaniam, A. Merk, R. Grisshammer, 2020, IUCrJ.

Protein Posttranslational Modification

James L. Hougland, J. E. Darling, Susan C. Flynn, 2013 .

Protein Posttranslational Modification

James L. Hougland, Susan C. Flynn, J. Darling, 2013 .

Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization

D. Esposito, F. McCormick, A. Merk, 2023, Proceedings of the National Academy of Sciences of the United States of America.