Fred Schaper

发表

JAK-STAT Signalling as Example for a Database-Supported Modular Modelling Concept

Monika Heiner, Wolfgang Marwan, Mary Ann Blätke, 2012, CMSB.

Designing Optimal Experiments to Discriminate Interaction Graph Models

Sandra Heise, Steffen Klamt, Sven Thiele, 2019, IEEE/ACM Transactions on Computational Biology and Bioinformatics.

JAK/STAT signalling--an executable model assembled from molecule-centred modules demonstrating a module-oriented database concept for systems and synthetic biology.

Monika Heiner, Wolfgang Marwan, Mary Ann Blätke, 2012, Molecular bioSystems.

A simple work flow for biologically inspired model reduction - application to early JAK-STAT signaling

Martin Mönnigmann, Anna Dittrich, Fred Schaper, 2011, BMC Systems Biology.

Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling.

Martin Mönnigmann, Anna Dittrich, Fred Schaper, 2012, Molecular bioSystems.

The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling

Steffen Waldherr, Michal Komorowski, Tomasz Jetka, 2019, Cell Communication and Signaling.

SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130*

Jens Schneider-Mergener, Fred Schaper, Peter C. Heinrich, 2003, The Journal of Biological Chemistry.

Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene.

Dieter Häussinger, Fred Schaper, Verena Keitel, 2007, Cellular signalling.

The zinc finger protein Gfi‐1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3

Fred Schaper, Thorsten Schmidt, T. Möröy, 2000, The EMBO journal.

Activation of NF-κB by IL-1β blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human γ-fibrinogen gene

Dieter Häussinger, Johannes G. Bode, Fred Schaper, 2007 .

Determinants governing the potency of STAT3 activation via the individual STAT3-recruiting motifs of gp130.

Fred Schaper, Ulrike Sommer, Serge Haan, 2006, Cellular signalling.

Interleukin-6 signalling: more than Jaks and STATs.

Anna Dittrich, Fred Schaper, F. Schaper, 2012, European journal of cell biology.

Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3 1

Rolf Rossaint, Fred Schaper, Serge Haan, 2003, The Journal of Immunology.

LPS and TNFα induce SOCS3 mRNA and inhibit IL‐6‐induced activation of STAT3 in macrophages

Dieter Häussinger, Fred Schaper, Jochen Schmitz, 1999, FEBS letters.