Rainer E. Martin

发表

Design and synthesis of conjugated materials for efficient optoelectronic devices

Andrew B. Holmes, Franco Cacialli, Jorgedo Morgado, 1999, Optics & Photonics.

Joint Meeting on Medicinal Chemistry in Vienna

Peter Mohr, Rainer E. Martin, Wylie Solang Palmer, 2005 .

PM3 geometry optimization and CNDO/S-CI computation of UV/Vis spectra of large organic structures: Program description and application to poly(triacetylene) hexamer and taxotere

Rainer E. Martin, François Diederich, Harold Baumann, 1999, J. Comput. Chem..

New routes to monomers and polymers for LEDs

Andrew B. Holmes, Franco Cacialli, Richard H. Friend, 2001, SPIE Optics + Photonics.

Neighborhood-preserving visualization of adaptive structure-activity landscapes: application to drug discovery.

Wolfgang Guba, Petra Schneider, Gisbert Schneider, 2011, Angewandte Chemie.

Synthesis of Light‐Emitting Conjugated Polymers for Applications in Electroluminescent Devices

Khai Leok Chan, Rainer E. Martin, Andrew B. Holmes, 2009 .

A carbohydrate-derived trifunctional scaffold for DNA-encoded libraries

Rainer E. Martin, A. Satz, Felix Gruber, 2017 .

Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors.

Jérôme Hert, Robert Abel, Lingle Wang, 2017, Journal of medicinal chemistry.

G protein-coupled receptor transmembrane binding pockets and their applications in GPCR research and drug discovery: a survey.

Rainer E. Martin, W. Guba, J. Slack, 2011, Current topics in medicinal chemistry.

Efficient blue–green light emitting poly(1,4-phenylene vinylene) copolymers

Franco Cacialli, Richard H. Friend, B. S. Chuah, 2000 .

Synthesis of Annulated Pyridines by Intramolecular Inverse‐Electron‐Demand Hetero‐Diels–Alder Reaction under Superheated Continuous Flow Conditions

Falk Morawitz, Rainer E. Martin, Alexander Alanine, 2012 .

Scale-Up of Flow-Assisted Synthesisof C2-Symmetric Chiral PyBoxLigands

Claudio Battilocchio, Steven V. Ley, Rainer E. Martin, 2012 .

Poly(triacetylene) Oligomers: Synthesis, Characterization, and Estimation of the Effective Conjugation Length by Electrochemical, UV/Vis, and Nonlinear Optical Methods

Peter Günter, Rainer E. Martin, Christian Bosshard, 1997 .

Structure−Property Relationships in Third-Order Nonlinear Optical Chromophores

Rik R. Tykwinski, Peter Günter, Rainer E. Martin, 1998 .

Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R–dependent manner

Rainer E. Martin, J. Holst, J. Pedersen, 2021, JCI insight.

Versatile synthesis of various conjugated aromatic homo- and copolymers

B. S. Chuah, Rainer E. Martin, R. Friend, 2001 .

Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice.

Rainer E. Martin, Rainer E Martin, Jens Pedersen, 2019, American journal of physiology. Endocrinology and metabolism.

Novel, non-peptidic somatostatin receptor subtype 5 antagonists improve glucose tolerance in rodents

Rainer E. Martin, B. Künnecke, A. Binggeli, 2010, Regulatory Peptides.

Dendritic rods with a poly(triacetylene) backbone: insulated molecular wires

Rainer E. Martin, Masato M. Ito, F. Diederich, 1998 .

Synthesis of annulated pyridines as inhibitors of aldosterone synthase (CYP11B2).

Rainer E. Martin, B. Kuhn, A. Mayweg, 2016, Organic & biomolecular chemistry.

Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys.

Rainer E. Martin, B. Kuhn, A. Kuglstatter, 2015, Journal of medicinal chemistry.

Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C-H bonds.

Rainer E. Martin, Robert Britton, Michael Meanwell, 2018, Chemical communications.

Direct photocatalytic fluorination of benzylic C-H bonds with N-fluorobenzenesulfonimide.

Rainer E. Martin, Matthew B. Nodwell, H. Knust, 2015, Chemical communications.

Photocatalytic synthesis of allylic trifluoromethyl substituted styrene derivatives in batch and flow.

Rainer E. Martin, E. Carreira, Nicole Pfeiffer, 2013, Organic letters.

Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists.

Rainer E. Martin, C. Bissantz, P. Mattei, 2013, Bioorganic & medicinal chemistry letters.

Remote Modulation of Amine Basicity by a Phenylsulfone and a Phenylthio Group

Rainer E. Martin, Björn Wagner, H. Fischer, 2007, ChemMedChem.

Design of Luminescent Polymers for Leds

Rainer E. Martin, R. Friend, F. Cacialli, 2001 .

Electronic Characteristics of Arylated Tetraethynylethenes: A Cooperative Computational and Electrochemical Investigation

Rainer E. Martin, F. Diederich, H. Lüthi, 1997 .

Photochemical trans‐cis Isomerization of Donor/Acceptor‐Substituted (E)‐Hex‐3‐ene‐1,5‐diynes (1,2‐Diethynylethenes, DEEs) and 3,4‐Diethynylhex‐3‐ene‐1,5‐diynes (Tetraethynylethenes, TEEs)

Rainer E. Martin, F. Diederich, R. Tykwinski, 1998 .

Photochemical trans–cis isomerisation of donor/acceptor-substituted (E)-hex-3-ene-1,5-diynes (1,2-diethynylethenes, DEEs) and 3,4-diethynylhex-3-ene-1,5-diynes (tetraethynylethenes, TEEs)

Rainer E. Martin, F. Diederich, H. Lüthi, 1998 .

Dendritic Rods with a Poly(triacetylene) Backbone: Insulated Molecular Wires.

Rainer E. Martin, Masato M. Ito, F. Diederich, 1998 .

Insulated Molecular Wires: Dendritic Encapsulation of Poly(triacetylene) Oligomers, Attempted Dendritic Stabilization of Novel Poly(pentaacetylene) Oligomers, and an Organometallic Approach to Dendritic Rods

Rainer E. Martin, Masato M. Ito, F. Diederich, 2001 .

Electronic Characteristics of Arylated Tetraethynylethenes: A Cooperative Computational and Electrochemical Investigation.

Rainer E. Martin, F. Diederich, J. Gisselbrecht, 1997 .

The copolymer route to new luminescent materials for LEDs

B. S. Chuah, Rainer E. Martin, R. Friend, 2000 .

The Kondrat'eva reaction in flow: direct access to annulated pyridines.

Rainer E. Martin, Thibaut Alzieu, Robert Britton, 2013, Organic letters.

Site-Selective, Late-Stage C-H 18 F-Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging.

Rainer E. Martin, F. Bénard, P. Schaffer, 2018, Angewandte Chemie.

Site-Selective, Late-Stage C-H 18 F-Fluorination on Unprotected Peptides for Positron Emission Tomography Imaging.

Rainer E. Martin, F. Bénard, P. Schaffer, 2018, Angewandte Chemie.

A convenient photocatalytic fluorination of unactivated C-H bonds.

Rainer E. Martin, Shira D. Halperin, Robert Britton, 2014, Angewandte Chemie.

Piperidinyl-nicotinamides as potent and selective somatostatin receptor subtype 5 antagonists.

Rainer E. Martin, L. Green, A. Binggeli, 2010, Bioorganic & medicinal chemistry letters.

Benzoxazole piperidines as selective and potent somatostatin receptor subtype 5 antagonists.

Rainer E. Martin, W. Guba, L. Polonchuk, 2009, Bioorganic & medicinal chemistry letters.

Multi-layer Polymer Light-emitting Diodes with 2,3-Dialkoxy-p-phenylene Vinylene and its Blends

Rainer E. Martin, T. Sano, A. Holmes, 2002 .

Predicting and Tuning Physicochemical Properties in Lead Optimization: Amine Basicities

Manfred Kansy, Rainer E. Martin, Stefanie Bendels, 2007, ChemMedChem.

μSR of conducting and non-conducting polymers

Rainer E. Martin, S. Blundell, A. Husmann, 2000 .

Ligand identification for G-protein-coupled receptors: a lead generation perspective.

Rainer E. Martin, Konrad H Bleicher, Luke G Green, 2004, Current opinion in chemical biology.

Intramolecular Inverse Electron-Demand [4 + 2] Cycloadditions of Ynamides with Pyrimidines: Scope and Density Functional Theory Insights.

Rainer E. Martin, M. Neuburger, Guillaume Duret, 2017, The Journal of organic chemistry.

Inverse Electron-Demand [4 + 2]-Cycloadditions of Ynamides: Access to Novel Pyridine Scaffolds.

Rainer E. Martin, M. Neuburger, Guillaume Duret, 2016, Organic letters.

A Convenient Late-Stage Fluorination of Pyridylic C-H Bonds with N-Fluorobenzenesulfonimide.

Rainer E. Martin, Matthew B. Nodwell, Robert Britton, 2016, Angewandte Chemie.

Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives† †Electronic supplementary information (ESI) available: Experimental procedures, purification and characterization data for all new compounds. See DOI: 10.1039/c8sc01221k

Rainer E. Martin, P. Schaffer, P. Prevost, 2018, Chemical science.

Electrostatic Effects Accelerate Decatungstate-Catalyzed C–H Fluorination Using [18F]- and [19F]NFSI in Small Molecules and Peptide Mimics

Rainer E. Martin, F. Bénard, P. Schaffer, 2019, ACS Catalysis.

Seamless integration of dose-response screening and flow chemistry: efficient generation of structure-activity relationship data of β-secretase (BACE1) inhibitors.

Remo Hochstrasser, Rainer E. Martin, Horst Vogel, 2014, Angewandte Chemie.

18F-Fluorination of Unactivated C-H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological Positron Emission Tomography Imaging Agents.

Rainer E. Martin, F. Bénard, P. Schaffer, 2017, Journal of the American Chemical Society.

Flow synthesis of annulated 5-aryl-substituted pyridines by tandem intramolecular inverse-electron-demand hetero-/retro-Diels–Alder reaction

Rainer E. Martin, Thibaut Alzieu, J. Aebi, 2013 .

Linear Monodisperse π-Conjugated Oligomers: Model Compounds for Polymers and More.

Rainer E. Martin, Rainer E Martin, François Diederich, 1999, Angewandte Chemie.

Converting oxazoles into imidazoles: new opportunities for diversity-oriented synthesis.

Rainer E. Martin, Thibaut Alzieu, Robert Britton, 2014, Chemical communications.

Evaluation of a flow-photochemistry platform for the synthesis of compact modules

Rainer E. Martin, M. Nettekoven, Bernd Puellmann, 2012 .

Cyclopropanation of 3,4-dihydro-1 H-benzo[e][1,4]diazepine-2,5-diones

Rainer E. Martin, O. Lack, 2005 .

Photocatalytic synthesis of allylic trifluoromethyl substituted styrene derivatives in batch and flow.

Rainer E. Martin, E. Carreira, Nicole Pfeiffer, 2013, Organic letters.

Synthesis of light-emitting conjugated polymers for applications in electroluminescent devices.

Khai Leok Chan, Rainer E. Martin, Rainer E Martin, 2009, Chemical reviews.

Determination of End-to-End Distances in a Series of TEMPO Diradicals of up to 2.8 nm Length with a New Four-Pulse Double Electron Electron Resonance Experiment.

Rainer E. Martin, F. Diederich, V. Gramlich, 1998, Angewandte Chemie.

Modulation of Pharmacologically Relevant Properties of Piperidine Derivatives by Functional Groups in an Equatorial or Axial β‐Position to the Amino Group

Rainer E. Martin, Björn Wagner, H. Fischer, 2020, Chembiochem : a European journal of chemical biology.

A Convenient Synthesis of Difluoroalkyl Ethers from Thionoesters using Silver(I) Fluoride.

Rainer E. Martin, P. Schaffer, Matthew B. Nodwell, 2019, Chemistry.

PM3 geometry optimization and CNDO/S‐CI computation of UV/Vis spectra of large organic structures: Program description and application to poly(triacetylene) hexamer and taxotere

Rainer E. Martin, F. Diederich, H. Baumann, 1999 .

2 H-1,2,3-Triazole-Based Dipeptidyl Nitriles: Potent, Selective, and Trypanocidal Rhodesain Inhibitors by Structure-Based Design.

Rainer E. Martin, F. Diederich, B. Kuhn, 2018, Journal of medicinal chemistry.

Preparation of 5-amino-6-oxo-1,6-dihydro[1,2,4]triazine-3-carboxylic acid derivatives and synthesis of compound libraries thereof

Rainer E. Martin, Christoph Kuratli, Romain Gambert, 2004 .

Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.

Steven V Ley, Rainer E. Martin, Rainer E Martin, 2011, ACS combinatorial science.

Monodisperse Poly(triacetylene) Rods: Synthesis of a 11.9 nm Long Molecular Wire and Direct Determination of the Effective Conjugation Length by UV/Vis and Raman Spectroscopies.

Rainer E. Martin, F. Diederich, T. Mäder, 1999, Angewandte Chemie.

Muon-spin relaxation study of anisotropic charge carrier motion in polyphenylene vinylene-based polymers

Rainer E. Martin, S. Blundell, A. Husmann, 2002 .

18F-Branched-Chain Amino Acids: Structure–Activity Relationships and PET Imaging Potential

Rainer E. Martin, F. Bénard, P. Schaffer, 2019, The Journal of Nuclear Medicine.

A Convenient Photocatalytic Fluorination of Unactivated C—H Bonds.

Rainer E. Martin, Shira D. Halperin, Robert Britton, 2014 .

Quaternary Ammonium Trifluoromethoxide Salts as Stable Sources of Nucleophilic OCF3.

Rainer E. Martin, R. Britton, Benson J. Jelier, 2020, Organic letters.

Identification of an N-oxide pyridine GW4064 analog as a potent FXR agonist.

Hans Richter, Rainer E. Martin, Rainer E Martin, 2009, Bioorganic & medicinal chemistry letters.

Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes.

Franz Schuler, Rainer E. Martin, Rainer E Martin, 2011, Bioorganic & medicinal chemistry letters.

Discovery of the first nonpeptidic, small-molecule, highly selective somatostatin receptor subtype 5 antagonists: a chemogenomics approach.

Wolfgang Guba, Rainer E. Martin, Luke G Green, 2007, Journal of medicinal chemistry.

Rainer E. Martin, P. Schaffer, Zheliang Yuan, 2018, Chemical Science.

Synthesis of acyl fluorides via photocatalytic fluorination of aldehydic C-H bonds.

Rainer E. Martin, Robert Britton, Michael Meanwell, 2018, Chemical communications.

A carbohydrate-derived trifunctional scaffold for medicinal chemistry library synthesis

Rainer E. Martin, H. Wessel, Amalia Estévez, 2018, Mediterranean Journal of Chemistry.

Anodic and Cathodic Electrochemically Generated Chemiluminescence in Conjugated Polymers

Rainer E. Martin, A. Holmes, D. Dini, 2002 .

Synthesis and physical investigation of donor-donor and acceptor-acceptor end-functionalized monodisperse poly(triacetylene) oligomers.

Rainer E. Martin, F. Diederich, J. Gisselbrecht, 2000, Chemistry.

Inverse Electron-Demand [4 + 2]-Cycloadditions of Ynamides: Access to Novel Pyridine Scaffolds.

Rainer E. Martin, M. Neuburger, Guillaume Duret, 2016, Organic letters.

Determination of End-to-End Distances in a Series of TEMPO Diradicals of up to 2.8 nm Length with a New Four-Pulse Double Electron Electron Resonance Experiment.

Rainer E. Martin, F. Diederich, V. Gramlich, 1998, Angewandte Chemie.

From astemizole to a novel hit series of small-molecule somatostatin 5 receptor antagonists via GPCR affinity profiling.

Wolfgang Guba, Harald Mauser, Martin Stahl, 2007, Journal of medicinal chemistry.