Damien A Wolfe

Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems

Sripriya Ravindra Kumar, V. Gradinaru, S. Mazmanian, 2022, Neuron.

Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors

Sripriya Ravindra Kumar, V. Gradinaru, J. Vielmetter, 2023, Science advances.

Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates

Sripriya Ravindra Kumar, B. Levi, E. Lein, 2023, bioRxiv.

Homologs of LEAFY and UNUSUAL FLORAL ORGANS Promote the Transition From Inflorescence to Floral Meristem Identity in the Cymose Aquilegia coerulea

E. Kramer, Cristina L Walcher-Chevillet, L. Holappa, 2019, Front. Plant Sci..

Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates

Sripriya Ravindra Kumar, B. Levi, E. Lein, 2023, Nature communications.

Human cell surface-AAV interactomes identify LRP6 as blood-brain-barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder

Miguel R. Chuapoco, V. Gradinaru, T. Chou, 2024, bioRxiv.

Human cell surface-AAV interactomes identify LRP6 as blood-brain barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder

Miguel R. Chuapoco, V. Gradinaru, T. Chou, 2024, Nature communications.