Dae‐Kee Kim

发表

TGF-β Type I Receptor Kinase Inhibitor EW-7197 Suppresses Cholestatic Liver Fibrosis by Inhibiting HIF1α-Induced Epithelial Mesenchymal Transition

Jeong-Seok Nam, So-Yeon Park, Y. Sheen, 2016, Cellular Physiology and Biochemistry.

Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis.

S. Gambhir, T. Wyss-Coray, Hui Zhang, 2007, The Journal of clinical investigation.

Inhibitors of histone deacetylases induce tumor-selective cytotoxicity through modulating Aurora-A kinase

Jung-Hyun Park, Sang Gyun Kim, Tae-You Kim, 2007, Journal of Molecular Medicine.

Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells

Jeong-Seok Nam, W. Lim, So-Yeon Park, 2015, Oncotarget.

Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes

S. Park, S. Nakae, T. Sumida, 2014, EMBO Molecular Medicine.

Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes

S. Park, S. Nakae, T. Sumida, 2013, EMBO molecular medicine.

Novel oral transforming growth factor‐β signaling inhibitor EW‐7197 eradicates CML‐initiating cells

Seong-Jin Kim, K. Naka, A. Hirao, 2016, Cancer science.

Vactosertib, TGF-β receptor I inhibitor, augments the sensitization of the anti-cancer activity of gemcitabine in pancreatic cancer.

B. Han, Soon-Sun Hong, J. Ryu, 2023, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

EW-7197, a Novel ALK-5 Kinase Inhibitor, Potently Inhibits Breast to Lung Metastasis

Jeong-Seok Nam, So-Yeon Park, Sol-Ji Kim, 2014, Molecular Cancer Therapeutics.

EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling

Jeong-Seok Nam, Y. Sheen, H. Woo, 2015, Cellular and Molecular Life Sciences.

Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-β signaling

S. S. Koh, Soojin Lee, Jaebeom Lee, 2016, Oncotarget.

An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition.

Jeong-Seok Nam, So-Yeon Park, Y. Sheen, 2014, Cancer letters.

EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation

Hong-Min Kim, Eun Soo Lee, C. Chung, 2022, Endocrinology and metabolism.

EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling

Jeong-Seok Nam, So-Yeon Park, Y. Sheen, 2014, Cellular and Molecular Life Sciences.

Anti-Cancer Effect of 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide in MCF-7 Human Breast Cancer

Y. Sheen, Dae-Kee Kim, K. Joung, 2012, Environmental health and toxicology.

Antiproliferative effect of trichostatin a and hc-toxin in T47D Human breast cancer cells

Y. Sheen, Dae-Kee Kim, K. Joung, 2004, Archives of pharmacal research.

EW‐7203, a novel small molecule inhibitor of transforming growth factor‐β (TGF‐β) type I receptor/activin receptor‐like kinase‐5, blocks TGF‐β1‐mediated epithelial‐to‐mesenchymal transition in mammary epithelial cells

Y. Sheen, Dae-Kee Kim, Chul-Yong Park, 2011, Cancer science.

Anti-Cancer Effect of IN-2001 in MDA-MB-231 Human Breast Cancer

Y. Sheen, Dae-Kee Kim, K. Joung, 2012, Biomolecules & therapeutics.

EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung.

Y. Sheen, C. Jin, Dae-Kee Kim, 2011, European journal of cancer.

Estrogen receptor enhances the antiproliferative effects of trichostatin A and HC-toxin in human breast cancer cells

Yhun Yhong Sheen, Y. Sheen, Kyung Nan Min, 2004, Archives of pharmacal research.

Altered Bone Morphogenetic Protein and Transforming Growth Factor-β Signaling in Rat Models of Pulmonary Hypertension: Potential for Activin Receptor-Like Kinase-5 Inhibition in Prevention and Progression of Disease

N. Morrell, M. Southwood, P. Upton, 2009, Circulation.

Effect of IN-1130, a small molecule inhibitor of transforming growth factor-beta type I receptor/activin receptor-like kinase-5, on prostate cancer cells.

Thomas J. Mueller, Seong-Jin Kim, C. Kwak, 2008, The Journal of urology.

Anti-Cancer Effect of IN-2001 in T47D Human Breast Cancer

Y. Sheen, Dae-Kee Kim, K. Joung, 2012, Biomolecules & therapeutics.

Increased transforming growth factor beta 1 expression mediates ozone-induced airway fibrosis in mice

M. Fanucchi, A. Katre, Rui-ming Liu, 2011, Inhalation toxicology.

Potent in vivo anti-breast cancer activity of IN-2001, a novel inhibitor of histone deacetylase, in MMTV/c-Neu mice.

G. Kong, Y. Sheen, Dae-Kee Kim, 2006, Cancer research.

Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease

J. Ock, J. Suh, J. Ryu, 2019, The world journal of men's health.

IN-1130, a novel transforming growth factor-beta type I receptor kinase (activin receptor-like kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease.

S. Park, Seong-Jin Kim, J. Han, 2009, The journal of sexual medicine.

Histone deacetylase inhibitor stimulateCYP3A4 proximal promoter activity in hepg2 cells

Y. Sheen, Dae-Kee Kim, J. Kim, 2004, Archives of pharmacal research.

Trichostatin a, a histone deacetylase inhibitor stimulateCYP3A4 proximal promoter activity in hepa-I cells

Y. Sheen, Dae-Kee Kim, M. Ahn, 2004, Archives of pharmacal research.

EW-7197, a Novel ALK-5 Kinase Inhibitor, Potently Inhibits Breast to Lung Metastasis

Jeong-Seok Nam, So-Yeon Park, Sol-Ji Kim, 2014, Molecular Cancer Therapeutics.