Neil L Kelleher

发表

A five-level classification system for proteoform identifications

Leah V Schaffer, Michael R Shortreed, Lloyd M Smith, 2019, Nature Methods.

A comprehensive pipeline for translational top-down proteomics from a single blood draw

Neil L Kelleher, Luca Fornelli, Timothy K Toby, 2018, Nature Protocols.

Using ProSight PTM and related tools for targeted protein identification and characterization with high mass accuracy tandem MS data.

Neil L Kelleher, Richard D Leduc, N. Kelleher, 2007, Current protocols in bioinformatics.

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

Lloyd M Smith, Ljiljana Paša-Tolić, Ying Ge, 2019, Nature Methods.

ProForma: A Standard Proteoform Notation.

Michael R Shortreed, Lloyd M Smith, Jared B Shaw, 2018, Journal of proteome research.

The first pilot project of the consortium for top‐down proteomics: A status report

Jared B Shaw, Nikola Tolić, Ljiljana Paša-Tolić, 2014, Proteomics.

Accurate Estimation of Context-Dependent False Discovery Rates in Top-Down Proteomics*

Richard D. LeDuc, Paul M Thomas, Ryan T Fellers, 2019, Molecular & Cellular Proteomics.

A Method for Label-Free, Differential Top-Down Proteomics.

Richard D LeDuc, Neil L Kelleher, Timothy K Toby, 2016, Methods in molecular biology.

Metabolomics and genomics in natural products research: complementary tools for targeting new chemical entities.

Neil L Kelleher, Nancy P Keller, Lindsay K Caesar, 2021, Natural product reports.

A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity.

Neil L Kelleher, Luca Fornelli, C Shad Thaxton, 2018, Journal of proteome research.

Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation.

Jared B Shaw, Yan Zhang, Paul M Thomas, 2013, Journal of the American Chemical Society.

Evaluation of the compact high-field orbitrap for top-down proteomics of human cells.

Paul M Thomas, Neil L Kelleher, Bryan P. Early, 2012, Journal of proteome research.

Elucidating the Rimosamide-Detoxin Natural Product Families and Their Biosynthesis Using Metabolite/Gene Cluster Correlations.

Ryan A McClure, Neil L Kelleher, R. J. Thomson, 2016, ACS chemical biology.

Miniaturized formats for efficient mass spectrometry-based proteomics and therapeutic development.

Neil L Kelleher, N. Kelleher, G. Valaskovic, 2002, Current topics in medicinal chemistry.

A Highly Productive, One-Pot Cell-Free Protein Synthesis Platform Based on Genomically Recoded Escherichia coli.

Michael C Jewett, Paul M Thomas, Neil L Kelleher, 2019, Cell chemical biology.

Advancing Top-down Analysis of the Human Proteome Using a Benchtop Quadrupole-Orbitrap Mass Spectrometer.

Ryan T Fellers, Richard D LeDuc, Neil L Kelleher, 2017, Journal of proteome research.

High-Throughput Analysis of Intact Human Proteins Using UVPD and HCD on an Orbitrap Mass Spectrometer.

Richard D. LeDuc, Paul M Thomas, Ryan T Fellers, 2017, Journal of proteome research.

Precise and Parallel Characterization of Coding Polymorphisms, Alternative Splicing, and Modifications in Human Proteins by Mass Spectrometry*S

Neil L Kelleher, N. Kelleher, Andrew J. Forbes, 2005, Molecular & Cellular Proteomics.

Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase.

Neil L Kelleher, Roberto Kolter, Christopher T Walsh, 2005, Proceedings of the National Academy of Sciences of the United States of America.

A researcher's guide to mass spectrometry‐based proteomics

Neil L Kelleher, Timothy K Toby, N. Kelleher, 2016, Proteomics.

Top down proteomics.

John R Yates, Neil L Kelleher, J. Yates, 2013, Analytical chemistry.

Top down proteomics of human membrane proteins from enriched mitochondrial fractions.

Paul M Thomas, Neil L Kelleher, Bryan P. Early, 2013, Analytical chemistry.

Metabologenomics: Correlation of Microbial Gene Clusters with Metabolites Drives Discovery of a Nonribosomal Peptide with an Unusual Amino Acid Monomer

Ryan A McClure, Neil L Kelleher, R. J. Thomson, 2016, ACS central science.

Dissecting non-ribosomal and polyketide biosynthetic machineries using electrospray ionization Fourier-Transform mass spectrometry.

Pieter C Dorrestein, Neil L Kelleher, P. Dorrestein, 2006, Natural product reports.

Precise characterization of human histones in the H2A gene family by top down mass spectrometry.

Neil L Kelleher, N. Kelleher, C. Mizzen, 2006, Journal of proteome research.

Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry.

Paul M Thomas, Neil L Kelleher, Kenneth R Durbin, 2012, Analytical chemistry.

Endogenous Peptide Discovery of the Rat Circadian Clock a Focused Study of the Suprachiasmatic Nucleus by Ultrahigh Performance Tandem Mass Spectrometry* □ S

Leonid Zamdborg, Ji Eun Lee, Jonathan V Sweedler, 2022 .

Large-scale Top-down Proteomics of the Human Proteome: Membrane Proteins, Mitochondria, and Senescence*

Paul M Thomas, Ryan T Fellers, Neil L Kelleher, 2013, Molecular & Cellular Proteomics.

Mass spectrometry-based discovery of circadian peptides

Jonathan V Sweedler, Neil L Kelleher, Martha U Gillette, 2008, Proceedings of the National Academy of Sciences.

Expansion for the Brachylophosaurus canadensis Collagen I Sequence and Additional Evidence of the Preservation of Cretaceous Protein.

Marshall Bern, Paul M Thomas, Neil L Kelleher, 2017, Journal of proteome research.

ProSight Lite: graphical software to analyze top-down mass spectrometry data.

Paul M Thomas, Ryan T Fellers, Richard D LeDuc, 2015, Proteomics.

Genome-wide high-throughput mining of natural-product biosynthetic gene clusters by phage display.

Pieter C Dorrestein, Neil L Kelleher, Sinisa Hrvatin, 2007, Chemistry & biology.

Identification and characterization of homologues of vertebrate beta-thymosin in the marine mollusk Aplysia californica.

Jonathan V Sweedler, Neil L Kelleher, Elena V Romanova, 2006, Journal of mass spectrometry : JMS.

Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics.

Ryan A McClure, Neil L Kelleher, James H. Tryon, 2018, ACS chemical biology.

A monovalent streptavidin with a single femtomolar biotin binding site

Pieter C Dorrestein, Neil L Kelleher, Mark Howarth, 2006, Nature Methods.

The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput.

Leonid Zamdborg, Ji Eun Lee, Paul M Thomas, 2010, Molecular bioSystems.

Identification and Characterization of Human Proteoforms by Top-Down LC-21 Tesla FT-ICR Mass Spectrometry.

Paul M Thomas, Ryan T Fellers, Richard D LeDuc, 2017, Journal of proteome research.

Detection and localization of protein modifications by high resolution tandem mass spectrometry.

Neil L Kelleher, Fanyu Meng, N. Kelleher, 2005, Mass spectrometry reviews.

Comprehensive Phosphoprotein Analysis of Linker Histone H1 from Tetrahymena thermophila*S

Scott A. Busby, Philip C Andrews, Neil L Kelleher, 2006, Molecular & Cellular Proteomics.

Bioinformatics Analysis of Top-Down Mass Spectrometry Data with ProSight Lite.

Paul M Thomas, Ryan T Fellers, Neil L Kelleher, 2016, Methods in molecular biology.

Accessing natural product biosynthetic processes by mass spectrometry.

Neil L Kelleher, N. Kelleher, Stefanie B. Bumpus, 2008, Current opinion in chemical biology.

Top-down characterization of endogenous protein complexes with native proteomics

Neil L Kelleher, Luca Fornelli, Luis F Schachner, 2017, Nature chemical biology.

Pervasive combinatorial modification of histone H3 in human cells

Neil L Kelleher, Benjamin A Garcia, B. Garcia, 2007, Nature Methods.

Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry.

Pieter C Dorrestein, Sylvie Garneau-Tsodikova, Neil L Kelleher, 2006, Biochemistry.

Shotgun annotation of histone modifications: a new approach for streamlined characterization of proteins by top down mass spectrometry.

Neil L Kelleher, N. Kelleher, James J Pesavento, 2004, Journal of the American Chemical Society.

Structure determination and interception of biosynthetic intermediates for the plantazolicin class of highly discriminating antibiotics.

Neil L Kelleher, Douglas A Mitchell, Jaeheon Lee, 2011, ACS chemical biology.

Mass spectrometric characterization of human histone H3: a bird's eye view.

Neil L Kelleher, N. Kelleher, C. Mizzen, 2006, Journal of proteome research.

Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval.

Leonid Zamdborg, Craig D Wenger, Neil L Kelleher, 2009, Journal of proteome research.

A Roadmap for Natural Product Discovery Based on Large-Scale Genomics and Metabolomics

Neil L Kelleher, Anthony W. Goering, N. Kelleher, 2014, Nature chemical biology.

Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids

Dieter Söll, Farren J. Isaacs, Michael C Jewett, 2015, Nature Biotechnology.

Epiproteomics: quantitative analysis of histone marks and codes by mass spectrometry.

Neil L Kelleher, Yupeng Zheng, N. Kelleher, 2016, Current opinion in chemical biology.

Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts*

David Fenyö, Henry Rodriguez, Paul M Thomas, 2015, Molecular & Cellular Proteomics.

Comparative top down proteomics of peripheral blood mononuclear cells from kidney transplant recipients with normal kidney biopsies or acute rejection

Richard D. LeDuc, Paul M Thomas, Ryan T Fellers, 2016, Proteomics.

Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics.

Leonid Zamdborg, Neil L Kelleher, N. Kelleher, 2013, Journal of proteomics.

Modern mass spectrometry for synthetic biology and structure-based discovery of natural products.

Neil L Kelleher, N. Kelleher, Matthew T Henke, 2016, Natural product reports.

Illuminating the dark matter of shotgun proteomics

Neil L Kelleher, N. Kelleher, Owen S Skinner, 2015, Nature Biotechnology.

Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa.

Masashi Narita, Ryan T Fellers, Neil L Kelleher, 2016, Journal of proteome research.

Quantitative peptidomics for discovery of circadian-related peptides from the rat suprachiasmatic nucleus.

Leonid Zamdborg, Ji Eun Lee, Jonathan V Sweedler, 2013, Journal of proteome research.

Evolutionary migration of a post-translationally modified active-site residue in the proton-pumping heme-copper oxygen reductases.

Todd J Martinez, Neil L Kelleher, James Hemp, 2006, Biochemistry.

Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk

Henry Rodriguez, Ryan T Fellers, Richard D LeDuc, 2018, Proceedings of the National Academy of Sciences.

Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids

Michael C Jewett, Paul M Thomas, Neil L Kelleher, 2018, Nature Communications.