Kazuhito Harada

JTP‐109192, a novel G protein‐coupled receptor 119 agonist, prevents atherosclerosis by improving hypercholesterolaemia in congenic spontaneously hyperlipidaemic mice

Takahisa Yamada, T. Sasase, T. Ohta, 2020, Clinical and experimental pharmacology & physiology.

Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure.

Junji Mizukami, Shinji Yata, I. Matsuda, 2018, Bioorganic & medicinal chemistry letters.

Methyl and Fluorine Effects in Novel Orally Bioavailable Keap1-Nrf2 PPI Inhibitor.

Naoki Ogawa, A. Nomura, T. Adachi, 2023, ACS medicinal chemistry letters.

Discovery of a potent and short-acting oral calcilytic with a pulsatile secretion of parathyroid hormone.

K. Fukuda, Hiromasa Hashimoto, Teruhiko Inoue, 2011, ACS medicinal chemistry letters.

Enantioselective addition of ketene silyl acetals to nitrones catalyzed by chiral titanium complexes. Synthesis of optically active beta-amino acids.

T. Kawakami, Y. Imada, S. Murahashi, 2002, Journal of the American Chemical Society.

Chronic treatment of JTP‐109192, a novel G‐protein coupled receptor 119 agonist, improves metabolic abnormalities in Zucker Fatty rats

Takahisa Yamada, T. Sasase, T. Ohta, 2019, Clinical and experimental pharmacology & physiology.

Lead generation and optimization of novel GPR119 agonists with a spirocyclic cyclohexane structure.

Junji Mizukami, S. Fukuda, Takashi Watanabe, 2019, Bioorganic & medicinal chemistry letters.

Optimization of oxadiazole derivatives with a spirocyclic cyclohexane structure as novel GPR119 agonists.

Junji Mizukami, S. Fukuda, Takashi Watanabe, 2019, Bioorganic & Medicinal Chemistry Letters.

Screening approaches for the identification of Nrf2-Keap1 protein-protein interaction inhibitors targeting hot spot residues.

A. Nomura, Y. Hantani, K. Yamaguchi, 2023, SLAS discovery : advancing life sciences R & D.