P. Narayanasamy

发表

Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF.

P. Brennan, D. Crick, Hyungjin Eoh, 2010, Chemistry & biology.

Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.

P. Brennan, T. Parish, D. Crick, 2009, Chemistry & biology.

Development of potential broad spectrum antimicrobials using C2-symmetric 9-fluorenone alkyl amine.

S. Hinrichs, M. A. Larson, Prabagaran Narayanasamy, 2016, Bioorganic & medicinal chemistry letters.

Chemoenzymatic synthesis of Park’s nucleotide: toward the development of high-throughput screening for MraY inhibitors

D. Crick, S. Mahapatra, M. Kurosu, 2007 .

Dual Inhibition of Klebsiella pneumoniae and Pseudomonas aeruginosa Iron Metabolism using Gallium Porphyrin and Gallium Nitrate.

B. Britigan, Prabagaran Narayanasamy, Seoung-ryoung Choi, 2019, ACS infectious diseases.

Gallium nanoparticles facilitate phagosome maturation and inhibit growth of virulent Mycobacterium tuberculosis in macrophages

Prabagaran Narayanasamy, B. Britigan, Prabagaran Narayanasamy, 2017, PloS one.

DosS Responds to a Reduced Electron Transport System To Induce the Mycobacterium tuberculosis DosR Regulon

M. Voskuil, D. Crick, Prabagaran Narayanasamy, 2010, Journal of bacteriology.

Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non‐replicating persistence

J. C. Hinshaw, R. Slayden, D. Crick, 2009, Molecular microbiology.

Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE.

D. Crick, Hyungjin Eoh, P. Narayanasamy, 2008, Tetrahedron letters.

Flavonoid Enhances the Glyoxalase Pathway in Cerebellar Neurons to Retain Cellular Functions

P. Narayanasamy, J. Frandsen, 2017, Scientific Reports.

Effect of Cannabidiol on the Neural Glyoxalase Pathway Function and Longevity of Several C. elegans Strains Including a C. elegans Alzheimer's Disease Model.

Prabagaran Narayanasamy, Joel Frandsen, P. Narayanasamy, 2022, ACS chemical neuroscience.

Neural Glyoxalase Pathway Enhancement by Morin Derivatives in an Alzheimer's Disease Model.

Prabagaran Narayanasamy, Seoung-ryoung Choi, Joel Frandsen, 2020, ACS chemical neuroscience.

Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway

Prabagaran Narayanasamy, Joel Frandsen, P. Narayanasamy, 2017, Redox biology.

Synthesis of azide derivative and discovery of glyoxalase pathway inhibitor against pathogenic bacteria.

Yiran Wang, Benson J. Edagwa, Prabagaran Narayanasamy, 2013, Bioorganic & medicinal chemistry letters.

Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection

A. Epstein, H. Gendelman, R. High, 2013, Journal of Neuroimmune Pharmacology.

Biochemical and Biologic Characterization of Exosomes and Microvesicles as Facilitators of HIV-1 Infection in Macrophages

Wei Zhang, H. Gendelman, Irena Kadiu, 2012, The Journal of Immunology.

Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular Pseudomonas aeruginosa and Acinetobacter baumannii

B. Britigan, Prabagaran Narayanasamy, Seoung-ryoung Choi, 2019, Antimicrobial Agents and Chemotherapy.

Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors

Lina Castro, T. Parish, Prabagaran Narayanasamy, 2019, Antimicrobial Agents and Chemotherapy.

Discovery of 1,4-Didydroxy-2-naphthoate Prenyltransferase Inhibitors: New Drug Leads for Multidrug-Resistant Gram-Positive Pathogens

D. Crick, M. Kurosu, Prabagaran Narayanasamy, 2007 .

Synthesis of chirally pure 1-deoxy-d-xylulose-5-phosphate : A substrate for IspC assay to determine M. tb inhibitor.

Benson J. Edagwa, Prabagaran Narayanasamy, P. Narayanasamy, 2013, Chemical sciences journal.

Treatment of Virulent Mycobacterium tuberculosis and HIV Coinfected Macrophages with Gallium Nanoparticles Inhibits Pathogen Growth and Modulates Macrophage Cytokine Production

B. Britigan, Prabagaran Narayanasamy, Seoung-ryoung Choi, 2019, mSphere.

Ga(III) Nanoparticles Inhibit Growth of both Mycobacterium tuberculosis and HIV and Release of Interleukin-6 (IL-6) and IL-8 in Coinfected Macrophages

B. Britigan, Seoung-ryoung Choi, P. Narayanasamy, 2017, Antimicrobial Agents and Chemotherapy.

Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes

H. Gendelman, J. McMillan, Benson J. Edagwa, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Potential of N-acetylated-para-aminosalicylic acid to accelerate manganese enhancement decline for long-term MEMRI in rodent brain

H. Gendelman, J. McMillan, M. Boska, 2015, Journal of Neuroscience Methods.

Development of Gallium(III) as an Antimicrobial Drug Targeting Pathophysiologic Iron Metabolism of Human Pathogens.

B. Britigan, Prabagaran Narayanasamy, Seoung-ryoung Choi, 2023, ACS infectious diseases.

Discovery of bicyclic inhibitors against menaquinone biosynthesis.

S. Hinrichs, M. A. Larson, Prabagaran Narayanasamy, 2016, Future medicinal chemistry.

Gallium Porphyrin and Gallium Nitrate Synergistically Inhibit Mycobacterial species by Targeting Different Aspects of Iron/Heme Metabolism.

B. Britigan, Prabagaran Narayanasamy, B. Switzer, 2020, ACS infectious diseases.

Combining Gallium Protoporphyrin and Gallium Nitrate Enhances In Vitro and In Vivo Efficacy against Pseudomonas aeruginosa: Role of Inhibition of Bacterial Antioxidant Enzymes and Resultant Increase in Cytotoxic Reactive Oxygen Species.

B. Britigan, Prabagaran Narayanasamy, Seoung-ryoung Choi, 2022, ACS infectious diseases.

Prolonged-acting, Multi-targeting Gallium Nanoparticles Potently Inhibit Growth of Both HIV and Mycobacteria in Co-Infected Human Macrophages

B. Britigan, Prabagaran Narayanasamy, B. Switzer, 2015, Scientific Reports.

Synthesis, optimization, in vitro and in vivo study of bicyclic substituted amine as MenA inhibitor.

Seoung-ryoung Choi, P. Narayanasamy, 2021, Bioorganic & Medicinal Chemistry Letters.

Synthesis and in vitro Analysis of Novel Gallium Tetrakis(4-methoxyphenyl)porphyrin and its Long-acting Nanoparticle as a Potent Antimycobacterial Agent.

B. Britigan, Prabagaran Narayanasamy, Seoung-ryoung Choi, 2022, Bioorganic & medicinal chemistry letters.

Nanoparticulate β-Cyclodextrin with Gallium Tetraphenylporphyrin Demonstrates in Vitro and in Vivo Antimicrobial Efficacy against Mycobacteroides abscessus and Mycobacterium avium.

B. Britigan, Prabagaran Narayanasamy, Seoung-ryoung Choi, 2021, ACS infectious diseases.

In Vitro and In Vivo Antimicrobial Activity of an Oxidative Stress-Mediated Bicyclic Menaquinone Biosynthesis Inhibitor against MRSA.

Seoung-ryoung Choi, P. Narayanasamy, 2023, ACS infectious diseases.

HIV-1 Infection in Macrophages of Exosomes and Microvesicles as Facilitators Biochemical and Biologic Characterization of

H. Gendelman, Irena Kadiu, P. Dash, 2012 .

Potential Mitigation, Prophylactics, and Treatments to Overcome COVID- 19

Prabagaran Narayanasamy, P. Narayanasamy, 2021, Coronaviruses.

Novel long-chain compounds with both immunomodulatory and MenA inhibitory activities against Staphylococcus aureus and its biofilm

Seoung-ryoung Choi, P. Narayanasamy, J. Frandsen, 2017, Scientific Reports.

Antimicrobial Activity of Gallium(III) Compounds: Pathogen-Dependent Targeting of Multiple Iron/Heme-Dependent Biological Processes

Seoung-ryoung Choi, P. Narayanasamy, Mohammed A Hassan, 2024, Current issues in molecular biology.