Melissa Seman

H3K9 methylation enhances HP1-associated epigenetic silencing complex assembly and suppresses off-chromatin binding

Peter L. Freddolino, J. Biteen, Ziyuan Chen, 2023 .

The establishment of HP1-independent heterochromatin reveals an essential role for HP1 proteins in maintaining epigenetic memory

Ajay Larkin, K. Ragunathan, Fengting Huang, 2023, bioRxiv.

Mapping the dynamics of epigenetic adaptation during heterochromatin misregulation

Ahmad S. Khalil, Ajay Larkin, K. Ragunathan, 2023, bioRxiv.

Tracking live-cell single-molecule dynamics enables measurements of heterochromatinassociated protein-protein interactions

J. Biteen, Ziyuan Chen, Saikat Biswas, 2023, bioRxiv.

Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation.

Ajay Larkin, K. Ragunathan, C. Kunze, 2024, Developmental cell.

Uncoupling the distinct functions of HP1 proteins during heterochromatin establishment and maintenance

Ajay Larkin, K. Ragunathan, Fengting Huang, 2023, bioRxiv.

Identification of a novel, tunable interface in the S.pombe HP1 protein, Swi6, that underpins epigenetic inheritance

J. Biteen, Ziyuan Chen, Ajay Larkin, 2023, bioRxiv.