Rahul A. Bharadwaj

发表

Influence of Alzheimer’s disease related neuropathology on local microenvironment gene expression in the human inferior temporal cortex

J. Kleinman, K. Martinowich, T. Hyde, 2023, bioRxiv.

The Mind and its Nucleosomes – Chromatin (dys)Regulation in Major Psychiatric Disease

S. Akbarian, C. Peter, Rahul A Bharadwaj, 2013 .

Setdb 1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit

C. Connor, S. Akbarian, M. Jakovcevski, 2017 .

Setdb1 Histone Methyltransferase Regulates Mood-Related Behaviors and Expression of the NMDA Receptor Subunit NR2B

F. A. Schroeder, C. Connor, S. Akbarian, 2010, The Journal of Neuroscience.

Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer’s disease

J. Kleinman, D. Weinberger, V. Mattay, 2018, bioRxiv.

The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

J. Kleinman, K. Martinowich, T. Hyde, 2022, bioRxiv.

Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition

Erica Y. Shen, V. Haroutunian, P. Sklar, 2014, Neuron.

Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions

J. Kleinman, A. Monaco, Qiang Chen, 2023, Science advances.

Prefrontal Cortical Dysfunction After Overexpression of Histone Deacetylase 1

S. Akbarian, M. Jakovcevski, A. Mitchell, 2013, Biological Psychiatry.

Neurobiology of Disease Conserved Chromosome 2 q 31 Conformations Are Associated with Transcriptional Regulation of GAD 1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia

W. Bunney, M. Vawter, S. Akbarian, 2017 .

Conserved Chromosome 2q31 Conformations Are Associated with Transcriptional Regulation of GAD1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia

Yan Jiang, Winfried Krueger, Marquis P. Vawter, 2013, The Journal of Neuroscience.

The Genome in Three Dimensions: A New Frontier in Human Brain Research

Y. Hurd, S. Akbarian, K. Mirnics, 2014, Biological Psychiatry.

Human-Specific Histone Methylation Signatures at Transcription Start Sites in Prefrontal Neurons

Jessica L. Crisci, Z. Weng, E. Rogaev, 2012, PLoS biology.

Neuroepigenetics of Schizophrenia.

G. Ursini, Rahul A Bharadwaj, G. Punzi, 2018, Progress in molecular biology and translational science.

THE GENOME IN 3D: A NEW FRONTIER IN HUMAN BRAIN RESEARCH

Y. Hurd, S. Akbarian, A. Mitchell, 2014 .

Orthogonal approaches required to measure proteasome composition and activity in mammalian brain tissue

J. Kleinman, T. Hyde, S. S. Margolis, 2023, The Journal of biological chemistry.

Molecular mechanisms and timing of cortical immune activation in schizophrenia.

T. Hyde, Rahul A. Bharadwaj, 2015, The American journal of psychiatry.

Word Count: 9184 Tables/Figures: 7 Decoding shared versus divergent transcriptomic signatures across cortico-amygdala circuitry in PTSD and depressive disorders

J. Kleinman, D. Williamson, K. Martinowich, 2022 .

Pathologic Implications for Microtubule-Associated Protein 2 in Schizophrenia Primary Auditory Cortex

J. Kleinman, Rahul A. Bharadwaj, 2015, Biological Psychiatry.

Alzheimer Lesions in the Autopsied Brains of People 30 to 50 Years of Age

J. Kleinman, B. Crain, J. Troncoso, 2015, Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.

Regulation of Higher Order Chromatin at GRIN2B and GAD1 Genetic Loci in Human and Mouse Brain: A Dissertation

Rahul A Bharadwaj, Rahul A. Bharadwaj, 2013 .

SUFI: an automated approach to spectral unmixing of fluorescent multiplex images captured in mouse and post-mortem human brain tissues

J. Kleinman, A. Jaffe, T. Hyde, 2021, bioRxiv.

SUFI: An automated approach to spectral unmixing of fluorescent biological images

J. Kleinman, A. Jaffe, T. Hyde, 2022 .

Genetic risk mechanisms of posttraumatic stress disorder in the human brain

J. Kleinman, D. Weinberger, V. Mattay, 2016, Journal of neuroscience research.

Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.

Manolis Kellis, C. Nievergelt, K. Ressler, 2023, The American journal of psychiatry.

Implementation and clinical characteristics of a posttraumatic stress disorder brain collection

J. Kleinman, T. Hyde, A. Deep-Soboslay, 2018, Journal of neuroscience research.

The gene expression landscape of the human locus coeruleus revealed by single-nucleus and spatially-resolved transcriptomics

J. Kleinman, K. Martinowich, T. Hyde, 2023, bioRxiv.

2 ( NR 2 B ) Subunit ε Neurons From Mice Lacking the Mediated Synaptic Currents in − Fast NMDA Receptor

Y. Yanagawa, P. Sah, C. Connor, 2000 .

Alzheimer Lesions in the Autopsied Brains of People 30 to 50 Years of Age

J. Kleinman, B. Crain, J. Troncoso, 2015, Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.

Conserved Chromosome 2q31 Conformations Are Associated with Transcriptional Regulation of GAD1 GABA Synthesis Enzyme and Altered in Prefrontal Cortex of Subjects with Schizophrenia

W. Bunney, M. Vawter, S. Akbarian, 2013, The Journal of Neuroscience.

Decoding shared versus divergent transcriptomic signatures across cortico-amygdala circuitry in PTSD and depressive disorders

J. Kleinman, D. Williamson, K. Martinowich, 2021, bioRxiv.

Single-cell multi-cohort dissection of the schizophrenia transcriptome

Kelsey S. Montgomery, Annie W Shieh, Alex A. Pollen, 2022, Science.

Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood

G. Pertea, C. Nievergelt, N. Seyfried, 2024, Science.