Aki Pui‐Wah Tse

发表

Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses.

Yan Zhang, C. C. Wong, D. K. Chiu, 2022, Journal of hepatology.

Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma

I. Ng, C. C. Wong, F. H. Tsang, 2017, Nature Communications.

Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer.

I. Ng, C. C. Wong, Lai Wei, 2021, Cell reports.

Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26

I. Ng, C. C. Wong, D. K. Chiu, 2016, Hepatology.

Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer

I. Ng, C. C. Wong, F. H. Tsang, 2018, Oncogenesis.

Polo‐like kinase 4 inhibitor CFI‐400945 suppresses liver cancer through cell cycle perturbation and eliciting antitumor immunity

D. Cescon, T. Mak, P. Khong, 2022, Hepatology.

Transketolase counteracts oxidative stress to drive cancer development

Chun-Ming Wong, Zongwei Cai, I. Ng, 2016, Proceedings of the National Academy of Sciences.

Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development

I. Ng, C. C. Wong, D. K. Chiu, 2023, Science advances.

Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma

I. Ng, C. C. Wong, F. H. Tsang, 2017, The Journal of clinical investigation.

Lysyl oxidase‐like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma

I. Ng, C. C. Wong, Yanping Huang, 2014, Hepatology.

NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma

I. Ng, C. C. Wong, M. Wong, 2016, Clinical Cancer Research.

Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

I. Ng, C. C. Wong, D. K. Chiu, 2022, Nature communications.

Switching of Pyruvate Kinase Isoform L to M2 Promotes Metabolic Reprogramming in Hepatocarcinogenesis

I. Ng, C. C. Wong, F. H. Tsang, 2014, PloS one.

Title Switching of pyruvate kinase isoform L to M 2 promotesmetabolic reprogramming in hepatocarcinogenesis

I. Ng, C. C. Wong, D. K. Chiu, 2014 .

Genome‐Wide CRISPR/Cas9 Library Screening Revealed Dietary Restriction of Glutamine in Combination with Inhibition of Pyruvate Metabolism as Effective Liver Cancer Treatment

C. C. Wong, Aki Pui-Wah Tse, Derek Lee, 2022, Advanced science.

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma

S. Lowe, I. Ng, C. C. Wong, 2019, Hepatology.

Ferroptosis Suppressor Protein 1 Inhibition Promotes Tumor Ferroptosis and Anti-tumor Immune Responses in Liver Cancer

I. Ng, C. C. Wong, C. Goh, 2023, Cellular and molecular gastroenterology and hepatology.

Assessment of Stabilization and Activity of the HIFs Important for Hypoxia-Induced Signalling in Cancer Cells.

C. C. Wong, D. K. Chiu, David Kung-Chun Chiu, 2019, Methods in molecular biology.

CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma

D. Cescon, P. Khong, I. Ng, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Adaptive and Constitutive Activations of Malic Enzymes Confer Liver Cancer Multilayered Protection Against Reactive Oxygen Species

I. Ng, C. C. Wong, F. H. Tsang, 2021, Hepatology.

Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer

I. Ng, C. C. Wong, D. K. Chiu, 2022, Nature Communications.

Hypoxia inducible factor HIF-1 promotes myeloid-derived suppressor cells accumulation through ENTPD2/CD39L1 in hepatocellular carcinoma

I. Ng, C. C. Wong, I. Xu, 2017, Nature Communications.

Title Folate cycle enzyme MTHFD 1 L confers metabolic advantages inhepatocellular carcinoma

I. Ng, C. C. Wong, Derek Lee, 2022 .

NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma

I. Ng, C. C. Wong, M. Wong, 2016, Clinical Cancer Research.