A. Princiotto

发表

A Small-Molecule CD4-Mimetic Compound Protects Bone Marrow–Liver–Thymus Humanized Mice From HIV-1 Infection

J. Sodroski, B. Melillo, Amos B. Smith, 2018, The Journal of infectious diseases.

Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization.

J. Sodroski, J. Mascola, Judith M. LaLonde, 2013, ACS medicinal chemistry letters.

Strain-Dependent Activation and Inhibition of Human Immunodeficiency Virus Entry by a Specific PF-68742 Stereoisomer

Alon Herschhorn, Shijian Zhang, J. Sodroski, 2019, Journal of Virology.

A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge

J. Sodroski, Laura L. Sutherland, B. Haynes, 2018, Nature Communications.

Comparison of Uncleaved and Mature Human Immunodeficiency Virus Membrane Envelope Glycoprotein Trimers

Luis R. Castillo-Menendez, J. Sodroski, A. Finzi, 2018, Journal of Virology.

Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors

Alon Herschhorn, Christopher Gu, Youdong Mao, 2016, Journal of Virology.

Activation and Inactivation of Primary Human Immunodeficiency Virus Envelope Glycoprotein Trimers by CD4-Mimetic Compounds

Alon Herschhorn, J. Sodroski, B. Melillo, 2016, Journal of Virology.

Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Primates Neutralize Primary Human Immunodeficiency Viruses (HIV-1) Sensitized by CD4-Mimetic Compounds

H. Liao, J. Sodroski, B. Haynes, 2016, Journal of Virology.

Contribution of Intrinsic Reactivity of the HIV-1 Envelope Glycoproteins to CD4-Independent Infection and Global Inhibitor Sensitivity

J. Sodroski, Liping Wang, M. Seaman, 2011, PLoS pathogens.

Transitions to and from the CD4-Bound Conformation Are Modulated by a Single-Residue Change in the Human Immunodeficiency Virus Type 1 gp120 Inner Domain

J. Sodroski, E. Freire, P. Kwong, 2009, Journal of Virology.

Inhibiting Early-Stage Events in HIV-1 Replication by Small-Molecule Targeting of the HIV-1 Capsid

R. Ptak, J. Sodroski, F. Krebs, 2012, Journal of Virology.

Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.

J. Sodroski, R. Wyatt, Judith M. LaLonde, 2008, Structure.

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

J. Sodroski, L. Walensky, J. Supko, 2010, Proceedings of the National Academy of Sciences.

Short Communication: Small-Molecule CD4 Mimetics Sensitize HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity by Antibodies Elicited by Multiple Envelope Glycoprotein Immunogens in Nonhuman Primates.

J. Sodroski, B. Haynes, B. Hahn, 2016, AIDS research and human retroviruses.

CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies

H. Liao, J. Sodroski, B. Haynes, 2014, Journal of Virology.

Small-Molecule CD 4 Mimics Interact with a Highly Conserved Pocket on HIV-1 gp 120

J. Sodroski, R. Wyatt, Judith M. LaLonde, 2018 .

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement.

R. Ptak, N. Madani, Amy M. Princiotto, 2014, Bioorganic & medicinal chemistry letters.

Soluble CD4 and CD4-Mimetic Compounds Inhibit HIV-1 Infection by Induction of a Short-Lived Activated State

J. Sodroski, Liping Wang, Amy M. Princiotto, 2009, PLoS pathogens.

Small-Molecule CD4-Mimics: Structure-Based Optimization of HIV-1 Entry Inhibition.

J. Sodroski, Judith M. LaLonde, W. Hendrickson, 2016, ACS medicinal chemistry letters.

Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein

Alon Herschhorn, Christopher Gu, Youdong Mao, 2017, Virology Journal.

Culture of pulmonary artery endothelial cells from pulmonary artery catheter balloon tips: considerations for use in pulmonary vascular disease

P. Quesenberry, M. Dooner, D. McGuirl, 2020, European Respiratory Journal.

A CD4-mimetic compound enhances vaccine efficacy against stringent immunodeficiency virus challenge

J. Sodroski, Laura L. Sutherland, B. Haynes, 2018, Nature Communications.

Structure-based design, synthesis, and characterization of dual hotspot small-molecule HIV-1 entry inhibitors.

Alexander W. Sun, J. Sodroski, J. Mascola, 2012, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.

Young Do Kwon, Joel R Courter, Peter D Kwong, 2011, Bioorganic & medicinal chemistry.

Liposomes for HIV prophylaxis.

J. Sodroski, R. Langer, D. Zurakowski, 2011, Biomaterials.

Liposomes for HIV prophylaxis.

J. Sodroski, R. Langer, D. Zurakowski, 2011, Biomaterials.

Comparison of Uncleaved and Mature Human Immunodeficiency Virus Membrane Envelope Glycoprotein Trimers

Luis R. Castillo-Menendez, J. Sodroski, A. Finzi, 2018, Journal of Virology.

CD4-Mimetic Small Molecules Sensitize Human Immunodeficiency Virus to Vaccine-Elicited Antibodies

J. Sodroski, B. Haynes, R. Wyatt, 2014, Journal of Virology.