J. Lopez

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The cytoplasmic domain of glycoprotein (GP) Ibalpha constrains the lateral diffusion of the GP Ib-IX complex and modulates von Willebrand factor binding.

J. A. López, V. Afshar-Kharghan, C. Li, 1997, Biochemistry.

Von Willebrand factor present in fibrillar collagen enhances platelet adhesion to collagen and collagen‐induced platelet aggregation

A. Bernardo, J. A. López, M. Crúz, 2004, Journal of thrombosis and haemostasis : JTH.

Mapping and comparison of the B-cell epitopes recognized on the Plasmodium vivax circumsporozoite protein by immune Colombians and immunized Aotus monkeys.

S. Herrera, M. Arévalo-Herrera, G. Corradin, 1998, Annals of tropical medicine and parasitology.

Bernard-Soulier syndrome.

J. A. López, M. Berndt, R. Andrews, 1998, Blood.

Characterization of two antigenic sites recognized by neutralizing monoclonal antibodies directed against the fusion glycoprotein of human respiratory syncytial virus.

J. Melero, J. Furze, S. Wyld, 1992, The Journal of general virology.

Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein.

S. Hoffman, N. Fasel, H. Matile, 1995, Molecular immunology.

Investigation of the effect of monocytes with Papua New Guinea sera on Plasmodium falciparum in culture.

M. Alpers, C. Rzepczyk, K. Anderson, 1988, International journal for parasitology.

Molecular mechanisms of platelet adhesion and activation.

José A López, J. A. López, M. Berndt, 1997, The international journal of biochemistry & cell biology.

Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoprotein.

K. Fujikawa, T. Papayannopoulou, G. Roth, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Synthetic polypeptides corresponding to the non-repeat regions from the circumsporozoite protein of Plasmodium falciparum: recognition by human T-cells and immunogenicity in owl monkeys.

S. Herrera, M. Arévalo-Herrera, J. A. López, 1997, Annals of tropical medicine and parasitology.

The platelet glycoprotein Ib-IX complex

José A López, J. A. López, J. Lopez, 2017 .

Shear-dependent rolling on von Willebrand factor of mammalian cells expressing the platelet glycoprotein Ib-IX-V complex.

L. McIntire, José A López, J. Dong, 1998, Blood.

Characterization of a human astrovirus serotype 2 structural protein (VP26) that contains an epitope involved in virus neutralization.

R. Glass, J. Carrascosa, A. Sánchez-Fauquier, 1994, Virology.

New light on an old story: von Willebrand factor binding to collagen

J. Chen, J. Lopez, 2006, Journal of thrombosis and haemostasis : JTH.

Expression of the amino-terminal domain of platelet glycoprotein Ib alpha: exploitation of a calmodulin tag for determination of its functional activity.

W. Ouwehand, M. Wardell, J. A. López, 2001, Protein expression and purification.

Ristocetin-dependent, but not botrocetin-dependent, binding of von Willebrand factor to the platelet glycoprotein Ib-IX-V complex correlates with shear-dependent interactions.

L. McIntire, José A López, J. A. López, 2001, Blood.

Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex.

J. Whisstock, L. McIntire, D. Kenny, 2000, Blood.

The platelet glycoprotein Ib‐IX‐V complex anchors lipid rafts to the membrane skeleton: implications for activation‐dependent cytoskeletal translocation of signaling molecules

K. Gaus, J. A. López, A. Munday, 2010, Journal of thrombosis and haemostasis : JTH.

An antigen-binding assay to determine the specificity of monoclonal antibodies against influenza virus and mapping of epitopes.

A. Sánchez-Fauquier, J. Melero, J. A. López, 1986, Journal of virological methods.

Microvesicle‐associated tissue factor and Trousseau's syndrome

U. Pendurthi, D. Dietzen, P. Thiagarajan, 2007, Journal of thrombosis and haemostasis : JTH.

Missense mutations of the glycoprotein (GP) Ib beta gene impairing the GPIb alpha/beta disulfide linkage in a family with giant platelet disorder.

T. Naoe, H. Saito, T. Kamiya, 1997, Blood.

Patterns of blood product use among patients with myelodysplastic syndrome

S. Ramsey, D. Blough, J. McCune, 2012, Vox sanguinis.

Role of glycoprotein V in the formation of the platelet high-affinity thrombin-binding site.

José A López, J. A. López, J. Dong, 1997, Blood.

Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib–IX complex

X. Mo, S. Luo, J. A. López, 2007, Journal of thrombosis and haemostasis : JTH.

Role of Kozak sequence polymorphism of platelet glycoprotein Ibalpha as a risk factor for coronary artery disease and catheter interventions.

M. Laule, G. Baumann, K. Stangl, 2001, Journal of the American College of Cardiology.

Kozak sequence polymorphism of the glycoprotein (GP) Ibalpha gene is a major determinant of the plasma membrane levels of the platelet GP Ib-IX-V complex.

José A López, J. A. López, Chester Q. Li, 1999, Blood.

The alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequence.

K. Fujikawa, E. Davie, G. Roth, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Role of carbohydrate modification in the production and secretion of human granulocyte macrophage colony-stimulating factor in genetically engineered and normal mesenchymal cells.

K. Kaushansky, J. A. López, C. B. Brown, 1992, Biochemistry.

Analysis of genetic variability and mapping of point mutations in influenza virus by the RNase A mismatch cleavage method.

M. Perucho, J. Melero, J. Ortín, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Mutant forms of the F protein of human respiratory syncytial (RS) virus induce a cytotoxic T lymphocyte response but not a neutralizing antibody response and only transient resistance to RS virus infection.

J. Melero, S. Wyld, R. Cook, 1996, The Journal of general virology.

Platelet glycoprotein Ibalpha Kozak polymorphism is associated with an increased risk of ischemic stroke.

G. Hankey, J. Eikelboom, José A López, 2001, Blood.

Simian virus 40-transformed adherent cells from human long-term marrow cultures: cloned cell lines produce cells with stromal and hematopoietic characteristics.

J. Nemunaitis, J. Singer, J. A. Lopez, 1987, Blood.

Inhibitory monoclonal antibody against a (myristylated) small-molecular-weight antigen from Plasmodium falciparum associated with the parasitophorous vacuole membrane

J. A. López, D. Stenzel, U. Kara, 1988, Infection and immunity.

Efficient plasma membrane expression of a functional platelet glycoprotein Ib-IX complex requires the presence of its three subunits.

C. C. Reynolds, J. Fox, José A López, 1992, The Journal of biological chemistry.

Receptors, rafts, and microvesicles in thrombosis and inflammation

J. A. López, J. A. LÓPEZ, I. DEL CONDE, 2005, Journal of Thrombosis and Haemostasis.

Distinct phenotypes of antigen-selected CD8 T cells emerge at different stages of an in vivo immune response.

H. Macdonald, P. Walker, T. Ohteki, 1995, Journal of immunology.

Cross-presentation of a human malaria CTL epitope is conformation dependent.

J. Fleming, C. Schmidt, J. A. López, 2006, Molecular immunology.

Synthetic microvessels

J. López, Y. Zheng, J. Lopez, 2013, Journal of thrombosis and haemostasis : JTH.

Human polymorphism of P-selectin glycoprotein ligand 1 attributable to variable numbers of tandem decameric repeats in the mucinlike region.

A. Marian, V. Afshar-Kharghan, E. Ludwig, 2001, Blood.

Analysis of genetic variability in human respiratory syncytial virus by the RNase A mismatch cleavage method: subtype divergence and heterogeneity.

J. Garcia, B. García-Barreno, J. Melero, 1990, Virology.

Rifampicin-dependent antibodies bind a similar or identical epitope to glycoprotein IX-specific quinine-dependent antibodies.

B. Chong, J. A. López, L. Gaudry, 2000, Blood.

Location of a highly conserved neutralizing epitope in the F glycoprotein of human respiratory syncytial virus

B. García-Barreno, J. Melero, A. Portela, 1990, Journal of virology.

Nucleotide sequence of the fusion and phosphoprotein genes of human respiratory syncytial (RS) virus Long strain: evidence of subtype genetic heterogeneity.

J. Melero, A. Portela, N. Villanueva, 1988, Virus research.

A point mutation in the F1 subunit of human respiratory syncytial virus fusion glycoprotein blocks its cell surface transport at an early stage of the exocytic pathway.

B. García-Barreno, J. Melero, A. Portela, 1996, The Journal of general virology.

Measuring the binding strength of single ligand–receptor pairs on cells: reply to a rebuttal

B. Anvari, M. Arya, J. A. Lopez, 2004 .

Glycoprotein Ib–IX‐mediated activation of integrin αIIbβ3: effects of receptor clustering and von Willebrand factor adhesion

B. Anvari, M. Arya, J. A. López, 2003 .

Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha.

E. Huizinga, H. Deckmyn, J. A. López, 2001, Blood.

Identification and characterization of endothelial glycoprotein Ib using viper venom proteins modulating cell adhesion.

M. Kowalska, J. A. López, S. Niewiarowski, 1999, Blood.

Sulfatides inhibit platelet adhesion to von Willebrand factor in flowing blood

L. McIntire, G. Borthakur, José A López, 2003, Journal of thrombosis and haemostasis : JTH.

Binding of platelet glycoprotein Ibβ through the convex surface of leucine‐rich repeats domain of glycoprotein IX

P. McEwan, J. Emsley, X. Mo, 2009, Journal of thrombosis and haemostasis : JTH.

The glycoprotein Ib-IX complex-specific monoclonal antibody SZ1 binds to a conformation-sensitive epitope on glycoprotein IX: implications for the target antigen of quinine/quinidine-dependent autoantibodies.

J. A. López, C. Li, S. Weisman, 1995, Blood.

Glycoprotein (GP) Ib beta is the critical subunit linking GP Ib alpha and GP IX in the GP Ib-IX complex. Analysis of partial complexes.

D. Sanan, José A López, J. A. López, 1994, The Journal of biological chemistry.

Subcellular site of expression and route of vaccination influence pulmonary eosinophilia following respiratory syncytial virus challenge in BALB/c mice sensitized to the attachment G protein.

J. Melero, G. Taylor, J. A. López, 1998, Journal of immunology.

Frame shift mutations as a novel mechanism for the generation of neutralization resistant mutants of human respiratory syncytial virus.

B. García-Barreno, J. Melero, A. Portela, 1990, The EMBO journal.

Plasmodium falciparum CS C-terminal fragment: preclinical evaluation and phase I clinical studies.

F. Spertini, G. Corradin, R. Audran, 1999, Parassitologia.

Unstable, low-level transmission of malaria on the Colombian Pacific Coast.

S. Herrera, G. Carrasquilla, J. A. López, 1997, Annals of tropical medicine and parasitology.

Necessity of conserved asparagine residues in the leucine-rich repeats of platelet glycoprotein Ib alpha for the proper conformation and function of the ligand-binding region.

L. McIntire, L. Sun, J. A. López, 2000, Biochemistry.

Direct binding of peptides to MHC class I molecules on living cells. Analysis at the single cell level.

J. Cerottini, I. Luescher, J. Lopez, 1992, Journal of Immunology.

Tyrosine sulfation of the glycoprotein Ib-IX complex: identification of sulfated residues and effect on ligand binding.

José A López, J. A. López, Chester Q. Li, 1994, Biochemistry.

Conformational constraints of conserved neutralizing epitopes from a major antigenic area of human respiratory syncytial virus fusion glycoprotein.

J. Melero, D. Andreu, J. A. López, 1993, The Journal of general virology.

Modulation by heparin of the interaction of the A1 domain of Von Willebrand factor with glycoprotein Ib.

P. Legendre, D. Baruch, D. Meyer, 1999, Blood.

Phosphorylation and subcellular localization of transmissible gastroenteritis virus nucleocapsid protein in infected cells.

J. M. González, E. Calvo, L. Enjuanes, 2005, The Journal of general virology.

Recognition of synthetic 104-mer and 102-mer peptides corresponding to N- and C-terminal nonrepeat regions of the Plasmodium falciparum circumsporozoite protein by sera from human donors.

R. Tolle, S. Herrera, M. Arévalo-Herrera, 1996, The American journal of tropical medicine and hygiene.

Polymorphism of human glycoprotein Ib alpha results from a variable number of tandem repeats of a 13-amino acid sequence in the mucin-like macroglycopeptide region. Structure/function implications.

J. A. López, B. Mccarthy, E. Ludwig, 1992, The Journal of biological chemistry.

Calmodulin binding to the C-terminus of the small-conductance Ca2+-activated K+ channel hSK1 is affected by alternative splicing.

M. Udden, R. Adachi, R. Sullivan, 2001, Biochemistry.

The membrane‐proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor

X. Mo, S. Luo, J. A. López, 2008, Journal of thrombosis and haemostasis : JTH.

Aggregation of mammalian cells expressing the platelet glycoprotein (GP) Ib-IX complex and the requirement for tyrosine sulfation of GP Ib alpha.

J. A. López, J. Dong, W. Hyun, 1995, Blood.

The diversity of antigen-specific TCR repertoires reflects the relative complexity of epitopes recognized.

H. Rammensee, J. Casanova, R. Lüthy, 1997, Human immunology.

Conformational studies of a short linear peptide corresponding to a major conserved neutralizing epitope of human respiratory syncytial virus fusion glycoprotein.

G. Rivas, J. Melero, D. Andreu, 1998, Biopolymers.

Normal cleavage of von Willebrand factor by ADAMTS‐13 in the absence of factor VIII in patients with severe hemophilia A

B. Konkle, M. Ling, D. Chung, 2013, Journal of thrombosis and haemostasis : JTH.