J. Jiang

发表

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Osteocytes regulate bone anabolic response to mechanical loading in male mice via activation of integrin α5

T. Guda, Jean X. Jiang, M. Riquelme, 2022, Bone Research.

Lymphatic Endothelial Cells Are Essential Components of the Subcapsular Sinus Macrophage Niche.

M. Bajénoff, Jean X. Jiang, W. Kastenmuller, 2019, Immunity.

Glucocorticoid-Induced Autophagy in Osteocytes

L. Bonewald, Jean X. Jiang, N. Lane, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Connexin Gap Junctions and Hemichannels Link Oxidative Stress to Skeletal Physiology and Pathology

Jean X. Jiang, Jingruo Zhang, M. Riquelme, 2021, Current Osteoporosis Reports.

Glucocorticoid‐Induced Autophagy Protects Osteocytes Against Oxidative Stress Through Activation of MAPK/ERK Signaling

Jean X. Jiang, M. Riquelme, Rekha Kar, 2018, JBMR plus.

Glucocorticoids and osteocyte autophagy.

Jean X. Jiang, N. Lane, W. Yao, 2013, Bone.

Glucocorticoid dose determines osteocyte cell fate

L. Bonewald, Jean X. Jiang, N. Lane, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin.

L. Bonewald, Jean X. Jiang, E. Sprague, 2005, Molecular biology of the cell.

Cataract-Causing Mutation of Human Connexin 46 Impairs Gap Junction, but Increases Hemichannel Function and Cell Death

Jean X. Jiang, Ji Xu, B. Nicholson, 2013, PloS one.

Connexin Gap Junctions and Hemichannels in Modulating Lens Redox Homeostasis and Oxidative Stress in Cataractogenesis

Jean X. Jiang, S. Gu, Yumeng Quan, 2021, Antioxidants.

Regulation of Connexin Gap Junctions and Hemichannels by Calcium and Calcium Binding Protein Calmodulin

Jean X. Jiang, Zhengping Hu, M. Riquelme, 2020, International journal of molecular sciences.

Cataract-associated connexin 46 mutation alters its interaction with calmodulin and function of hemichannels

Zhengping Hu, M. Riquelme, S. Gu, 2018, The Journal of Biological Chemistry.

Biological responses of osteocytic connexin 43 hemichannels to simulated microgravity

Jean X. Jiang, P. Shang, M. Riquelme, 2017, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Phosphorylation of Connexin 50 by Protein Kinase A Enhances Gap Junction and Hemichannel Function*

Jean X. Jiang, S. Weintraub, S. Gu, 2011, The Journal of Biological Chemistry.

Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases

Jean X. Jiang, D. Callaway, J. Jiang, 2015, Journal of Bone and Mineral Metabolism.

Effects of Mechanical Strain on the Function of Gap Junctions in Osteocytes Are Mediated through the Prostaglandin EP2 Receptor*

L. Bonewald, Jean X. Jiang, E. Sprague, 2003, Journal of Biological Chemistry.

Connexin 43 hemichannels and prostaglandin E2 release in anabolic function of the skeletal tissue to mechanical stimulation

Jiawei Wu, Jean X. Jiang, F. Acosta, 2023, Frontiers in Cell and Developmental Biology.

Connexin 43 hemichannels regulate mitochondrial ATP generation, mobilization, and mitochondrial homeostasis against oxidative stress

Jean X. Jiang, F. Acosta, Jingruo Zhang, 2022, bioRxiv.

Connexin 43 Hemichannels Regulate Osteoblast to Osteocyte Differentiation

Jean X. Jiang, S. Gu, Rui Hua, 2022, Frontiers in Cell and Developmental Biology.

Connexin 43 hemichannels protect bone loss during estrogen deficiency

T. Guda, R. Fajardo, Jean X. Jiang, 2019, Bone Research.

Mitogen-activated Protein Kinase (MAPK) Activated by Prostaglandin E2 Phosphorylates Connexin 43 and Closes Osteocytic Hemichannels in Response to Continuous Flow Shear Stress*

Jean X. Jiang, P. Lampe, M. Riquelme, 2015, The Journal of Biological Chemistry.

Gap junction and hemichannel functions in osteocytes.

Jean X. Jiang, H. Donahue, Alayna E. Loiselle, 2013, Bone.

Gap junctions and hemichannels in signal transmission, function and development of bone.

Jean X. Jiang, Rekha Kar, N. Batra, 2012, Biochimica et biophysica acta.

Original Article Regulation of cellular function by connexin hemichannels

Jean X. Jiang, Sirisha Burra, J. Jiang, 2011 .

Regulation of cellular function by connexin hemichannels.

Jean X. Jiang, Sirisha Burra, J. Jiang, 2011, International journal of biochemistry and molecular biology.

Mechanical Induction of PGE2 in Osteocytes Blocks Glucocorticoid-Induced Apoptosis Through Both the β-Catenin and PKA Pathways

Hai Qing, Mark L. Johnson, L. Bonewald, 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Prostaglandin Promotion of Osteocyte Gap Junction Function through Transcriptional Regulation of Connexin 43 by Glycogen Synthase Kinase 3/β-Catenin Signaling

Lynda F. Bonewald, L. Bonewald, Jean X. Jiang, 2009, Molecular and Cellular Biology.

Connexin 43 hemichannel opening associated with Prostaglandin E2 release is adaptively regulated by mechanical stimulation

Jean X. Jiang, Sirisha Burra, J. Jiang, 2009, Communicative & integrative biology.

Role of Gap Junction, Hemichannels, and Connexin 43 in Mineralizing in Response to Intermittent and Continuous Application of Parathyroid Hormone

Jean X. Jiang, Xuechun Xia, Priscilla P. Cherian, 2008, Cell communication & adhesion.

Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress.

Jean X. Jiang, Sirisha Burra, Arlene J. Siller-Jackson, 2007, Frontiers in bioscience : a journal and virtual library.

Expression of Functional Gap Junctions and Regulation by Fluid Flow in Osteocyte‐Like MLO‐Y4 Cells

L. Bonewald, Jean X. Jiang, E. Sprague, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Connexin mutation that causes dominant congenital cataracts inhibits gap junctions, but not hemichannels, in a dominant negative manner

Jean X. Jiang, M. Toloue, B. Nicholson, 2009, Journal of Cell Science.

Osteocytes and Bone Metastasis

Jean X. Jiang, M. Riquelme, Eduardo Cardenas, 2020, Frontiers in Endocrinology.

The Role of Connexin Channels in the Response of Mechanical Loading and Unloading of Bone

Jean X. Jiang, M. Riquelme, Huiyun Xu, 2020, International journal of molecular sciences.

Osteocytic Connexin Hemichannels Suppress Breast Cancer Growth and Bone Metastasis

Luzhe Sun, Jean X. Jiang, M. Riquelme, 2016, Oncogene.

Connexin 43 Channels Are Essential for Normal Bone Structure and Osteocyte Viability

Mark L. Johnson, Sherry L. Werner, T. Guda, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Connexin 43 Channels Protect Osteocytes Against Oxidative Stress–Induced Cell Death

Sherry L. Werner, Jean X. Jiang, M. Riquelme, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Mechanotransduction via the coordinated actions of integrins, PI3K signaling and Connexin hemichannels

Jean X. Jiang, M. Riquelme, S. Gu, 2021, Bone Research.

Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage

Jean X. Jiang, S. Gu, Changrui Wu, 2021, Redox biology.

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

M. Bennett, C. Naus, Jean X. Jiang, 2011, Journal of neurochemistry.

Negative feedback control of neuronal activity by microglia

Ukpong B. Eyo, Steven M. Graves, D. Surmeier, 2020, Nature.

Negative feedback control of neuronal activity by microglia

Ukpong B. Eyo, Steven M. Graves, D. Surmeier, 2020, Nature.

Connexin 43 Hemichannels Regulate the Expression of Wound Healing-Associated Genes in Human Gingival Fibroblasts

Jean X. Jiang, H. Larjava, L. Häkkinen, 2017, Scientific Reports.

ATP Is Required and Advances Cytokine-Induced Gap Junction Formation in Microglia In Vitro

Jean X. Jiang, J. Sáez, P. Sáez, 2013, Mediators of inflammation.

Connexin43 hemichannels contribute to cadmium-induced oxidative stress and cell injury.

Jean X. Jiang, M. Kitamura, H. Matsue, 2011, Antioxidants & redox signaling.

Gap junction- and hemichannel-independent actions of connexins.

Jean X. Jiang, S. Gu, J. Jiang, 2005, Biochimica et biophysica acta.

Regulation of Lens Connexin 45.6 by Apoptotic Protease, Caspase-3

Jean X. Jiang, S. Gu, J. X. Jiang, 2001, Cell communication & adhesion.

Osteocytic Connexin43 Channels Regulate Bone–Muscle Crosstalk

Jean X. Jiang, F. Acosta, P. Shang, 2021, Cells.

Connexin 43 Channels in Osteocytes Are Necessary for Bone Mass and Skeletal Muscle Function in Aged Male Mice

Jean X. Jiang, Dong-en Wang, Guobin Li, 2022, International journal of molecular sciences.

Connexin 43 Channels in Osteocytes Regulate Bone Responses to Mechanical Unloading

Jean X. Jiang, Meng Chen, P. Shang, 2020, Frontiers in Physiology.

Osteocytic connexin 43 channels affect fracture healing

Jean X. Jiang, P. Shang, Dong-en Wang, 2019, Journal of cellular physiology.

Gap junction and hemichannel‐independent actions of connexins on cell and tissue functions – An update

Jean X. Jiang, Jade Z. Zhou, J. Jiang, 2014, FEBS letters.

PGE2 Is Essential for Gap Junction-Mediated Intercellular Communication between Osteocyte-Like MLO-Y4 Cells in Response to Mechanical Strain.

L. Bonewald, Jean X. Jiang, E. Sprague, 2001, Endocrinology.

Developmental Regulation of the Direct Interaction between the Intracellular Loop of Connexin 45.6 and the C Terminus of Major Intrinsic Protein (Aquaporin-0)*

Jean X. Jiang, E. Lafer, X. Yin, 2005, Journal of Biological Chemistry.

Beyond the Channels: Adhesion Functions of Aquaporin 0 and Connexin 50 in Lens Development

Jean X. Jiang, S. Gu, Yumeng Quan, 2022, Frontiers in Cell and Developmental Biology.

Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis

Jean X. Jiang, M. Riquelme, S. Gu, 2021, iScience.

Connexin 50 and AQP0 are Essential in Maintaining Organization and Integrity of Lens Fibers

Jean X. Jiang, T. W. White, M. Riquelme, 2019, Investigative ophthalmology & visual science.

Lens Connexin 50 and AQP 0 are Essential in Maintaining Organization and Integrity of Lens Fibers

Jean X. Jiang, T. W. White, M. Riquelme, 2019 .

Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation

Jean X. Jiang, Zhengping Hu, T. W. White, 2017, Scientific Reports.

Connexin arrests the cell cycle through cytosolic retention of an E3 ligase

Qian Shi, J. Jiang, Jean X. Jiang, 2016, Molecular & cellular oncology.

Regional changes of AQP0-dependent square array junction and gap junction associated with cortical cataract formation in the Emory mutant mouse.

Jean X. Jiang, S. Gu, S. Biswas, 2014, Experimental eye research.

Aquaporin 0 enhances gap junction coupling via its cell adhesion function and interaction with connexin 50

Jean X. Jiang, Ji Xu, B. Nicholson, 2011, Journal of Cell Science.

Interaction of major intrinsic protein (aquaporin-0) with fiber connexins in lens development

Jean X. Jiang, X. S. Yu, J. Jiang, 2004, Journal of Cell Science.

The Development-associated Cleavage of Lens Connexin 45.6 by Caspase-3-like Protease Is Regulated by Casein Kinase II-mediated Phosphorylation*

Jean X. Jiang, S. Gu, Xinye Yin, 2001, The Journal of Biological Chemistry.

The SH3-binding domain of Cx43 participates in loop/tail interactions critical for Cx43-hemichannel activity

Jean X. Jiang, L. Leybaert, G. Bultynck, 2018, Cellular and Molecular Life Sciences.

Mechanosensitive piezo1 calcium channel activates connexin 43 hemichannels through PI3K signaling pathway in bone

Jean X. Jiang, F. Acosta, Jingruo Zhang, 2022, Cell & Bioscience.

Association of adenosine signaling gene signature with estrogen receptor-positive breast and prostate cancer bone metastasis

Luzhe Sun, Jean X. Jiang, V. Jin, 2022, Frontiers in Medicine.

Connexin hemichannels with prostaglandin release in anabolic function of bone to mechanical loading

T. Guda, Jean X. Jiang, M. Riquelme, 2021, bioRxiv.

Primary Osteocyte Supernatants Metabolomic Profiling of Two Transgenic Mice With Connexin43 Dominant Negative Mutants

Jean X. Jiang, Dong-en Wang, Guobin Li, 2021, Frontiers in Endocrinology.

Inhibition of astrocyte hemichannel improves recovery from spinal cord injury

Michael J. Mader, Jean X. Jiang, V. Bartanusz, 2021, JCI insight.

Connexin channel and its role in diabetic retinopathy

Jean X. Jiang, An-Fei Li, Dongjoon Kim, 2017, Progress in Retinal and Eye Research.

Blockage of hemichannels alters gene expression in osteocytes in a high magneto-gravitational environment.

Jean X. Jiang, P. Shang, S. Gu, 2017, Frontiers in bioscience.

N-Glycosylation influences transport, but not cellular trafficking, of a neuronal amino acid transporter SNAT1.

Jean X. Jiang, R. Iyer, S. Gu, 2016, The Biochemical journal.

Direct Regulation of Osteocytic Connexin 43 Hemichannels through AKT Kinase Activated by Mechanical Stimulation*

Jean X. Jiang, M. Riquelme, S. Gu, 2014, The Journal of Biological Chemistry.

14-3-3&thgr; facilitates plasma membrane delivery and function of mechanosensitive connexin 43 hemichannels

Jean X. Jiang, M. Riquelme, N. Batra, 2014, Journal of Cell Science.

Antibodies targeting extracellular domain of connexins for studies of hemichannels

Jean X. Jiang, M. Riquelme, S. Gu, 2013, Neuropharmacology.

“INTEGRINating” the connexin hemichannel function in bone osteocytes through the action of integrin α5

Jean X. Jiang, N. Batra, J. Jiang, 2012, Communicative & integrative biology.

Biological role of connexin intercellular channels and hemichannels.

Jean X. Jiang, M. Riquelme, Rekha Kar, 2012, Archives of biochemistry and biophysics.

Developmental Truncations of Connexin 50 by Caspases Adaptively Regulate Gap Junctions/Hemichannels and Protect Lens Cells against Ultraviolet Radiation*

Jean X. Jiang, S. Weintraub, Z. Hua, 2012, The Journal of Biological Chemistry.

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels

Gregory F Weber, L. Bonewald, Jean X. Jiang, 2012, Proceedings of the National Academy of Sciences.

Dark horse in osteocyte biology

Jean X. Jiang, D. Nicolella, Sirisha Burra, 2011 .

Dark horse in osteocyte biology: Glycocalyx around the dendrites is critical for osteocyte mechanosensing.

Daniel P Nicolella, Jean X. Jiang, D. Nicolella, 2011, Communicative & integrative biology.

Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels

Daniel P Nicolella, W. L. Francis, Jean X. Jiang, 2010, Proceedings of the National Academy of Sciences.

Adaptation of Connexin 43-Hemichannel Prostaglandin Release to Mechanical Loading*

L. Bonewald, Jean X. Jiang, E. Sprague, 2008, Journal of Biological Chemistry.

Promotion of lens epithelial-fiber differentiation by the C-terminus of connexin 45.6 – a role independent of gap junction communication

Jean X. Jiang, X. S. Yu, Eric A Banks, 2007, Journal of Cell Science.

Mechanical Loading Stimulates Expression of Connexin 43 in Alveolar Bone Cells in the Tooth Movement Model

Jean X. Jiang, D. Pavlin, S. Gu, 2006, Cell communication & adhesion.

Hemichannels Formed by Connexin 43 Play an Important Role in the Release of Prostaglandin E2by Osteocytes in Response to Mechanical Strain

Jean X. Jiang, Priscilla P. Cherian, J. Jiang, 2003, Cell communication & adhesion.

Differential expression of connexins during histogenesis of the chick retina

A. Kihara, D. E. Hamassaki, V. Paschon, 2008, Developmental neurobiology.