Olivier Michielin

发表

EADock: Docking of small molecules into protein active sites with a multiobjective evolutionary optimization

Aurélien Grosdidier, Vincent Zoete, Olivier Michielin, 2007, Proteins.

SwissBioisostere: a database of molecular replacements for ligand design

Olivier Michielin, Matthias Wirth, Vincent Zoete, 2012, Nucleic Acids Res..

Integrating radiomics into holomics for personalised oncology: from algorithms to bedside

Olivier Michielin, Roberto Gatta, Adrien Depeursinge, 2020, European Radiology Experimental.

Expanding molecular modeling and design tools to non‐natural sidechains

Olivier Michielin, Vincent Zoete, David Gfeller, 2012, J. Comput. Chem..

Protein pocket and ligand shape comparison and its application in virtual screening

Matthias Rarey, Friedrich Rippmann, Olivier Michielin, 2013, Journal of Computer-Aided Molecular Design.

Docking to heme proteins

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2009, J. Comput. Chem..

Compact imaging system with single-photon sensitivity and picosecond time resolution for fluorescence-guided surgery with lifetime imaging capability

Edoardo Charbon, Olivier Michielin, Claudio Bruschini, 2013, European Conference on Biomedical Optics.

MedCo: Enabling Privacy-Conscious Exploration of Distributed Clinical and Genomic Data

Jean-Pierre Hubaux, Jean Louis Raisaro, Olivier Michielin, 2017 .

SPHN/PHRT - MedCo in Action: Empowering the Swiss Molecular Tumor Board with Privacy-Preserving and Real-Time Patient Discovery

Jean-Pierre Hubaux, Jean Louis Raisaro, Olivier Michielin, 2020, MIE.

Fourier transform convolution integrals applied to generalized Born molecular volume

Olivier Michielin, Vincent Zoete, Thierry Schüpbach, 2009, J. Comput. Chem..

SwissSidechain: a molecular and structural database of non-natural sidechains

Olivier Michielin, Vincent Zoete, David Gfeller, 2012, Nucleic Acids Res..

Blind docking of 260 protein–ligand complexes with EADock 2.0

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2009, J. Comput. Chem..

Attracting cavities for docking. Replacing the rough energy landscape of the protein by a smooth attracting landscape

Olivier Michielin, Vincent Zoete, Thierry Schüpbach, 2015, J. Comput. Chem..

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

Olivier Michielin, Vincent Zoete, Antoine Daina, 2017, Scientific Reports.

SwissTargetPrediction: a web server for target prediction of bioactive small molecules

Aurélien Grosdidier, Olivier Michielin, Matthias Wirth, 2014, Nucleic Acids Res..

The SIB Swiss Institute of Bioinformatics’ resources: focus on curated databases

Oliver Horlacher, Damian Szklarczyk, Christian von Mering, 2015, Nucleic Acids Res..

Digitalization is Fueling a Revolution in Precision Oncology

Olivier Michielin, Michel A. Cuendet, M. Cuendet, 2021 .

Defining and searching for structural motifs using DeepView/Swiss-PdbViewer

Olivier Michielin, Vincent Zoete, Nicolas Guex, 2012, BMC Bioinformatics.

Fifteen years SIB Swiss Institute of Bioinformatics: life science databases, tools and support

Christian von Mering, Ron D. Appel, Evgeny M. Zdobnov, 2014, Nucleic Acids Res..

iLOGP: A Simple, Robust, and Efficient Description of n-Octanol/Water Partition Coefficient for Drug Design Using the GB/SA Approach

Olivier Michielin, Vincent Zoete, Antoine Daina, 2014, J. Chem. Inf. Model..

Fast docking using the CHARMM force field with EADock DSS

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2011, J. Comput. Chem..

SwissDock, a protein-small molecule docking web service based on EADock DSS

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2011, Nucleic Acids Res..

Protein-ligand binding free energy estimation using molecular mechanics and continuum electrostatics. Application to HIV-1 protease inhibitors

Olivier Michielin, Vincent Zoete, Martin Karplus, 2003, J. Comput. Aided Mol. Des..

Olivier Michielin, Vincent Zoete, Christophe Bovigny, 2016, J. Chem. Inf. Model..

Shaping the interaction landscape of bioactive molecules

Olivier Michielin, Vincent Zoete, David Gfeller, 2013, Bioinform..

Interplay between T Cell Receptor Binding Kinetics and the Level of Cognate Peptide Presented by Major Histocompatibility Complexes Governs CD8+ T Cell Responsiveness*

Olivier Michielin, Vincent Zoete, Pedro Romero, 2012, The Journal of Biological Chemistry.

Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators.

Olivier Michielin, Vincent Zoete, V. Zoete, 2007, Biochimica et biophysica acta.

Structural assessment of single amino acid mutations: application to TP53 function

Olivier Michielin, Holger Scheib, Vincent Zoete, 2006, Human mutation.

Dramatic response induced by vemurafenib in a BRAF V600E-mutated lung adenocarcinoma.

Olivier Michielin, Stefan Zimmermann, S. Peters, 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Inhibition of the shade avoidance response by formation of non‐DNA binding bHLH heterodimers

Olivier Michielin, Vincent Zoete, Séverine Lorrain, 2009, The EMBO journal.

Functional dynamics of PDZ binding domains: a normal-mode analysis.

Giovanni Dietler, Olivier Michielin, Fabio Cecconi, 2005, Biophysical journal.

T-Cell Receptors Binding Orientation over Peptide/MHC Class I Is Driven by Long-Range Interactions

Olivier Michielin, Vincent Zoete, Mathias Ferber, 2012, PloS one.

Identification of human IKK-2 inhibitors of natural origin (Part II): in Silico prediction of IKK-2 inhibitors in natural extracts with known anti-inflammatory activity.

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2011, European journal of medicinal chemistry.

Protein-protein interaction investigated by steered molecular dynamics: the TCR-pMHC complex.

Olivier Michielin, Michel A Cuendet, M. Cuendet, 2008, Biophysical journal.

Structure-Function Analyses Point to a Polynucleotide-Accommodating Groove Essential for APOBEC3A Restriction Activities

Olivier Michielin, Amalio Telenti, Vincent Zoete, 2010, Journal of Virology.

A Novel Population of Human Melanoma-Specific CD8 T Cells Recognizes Melan-AMART-1 Immunodominant Nonapeptide but Not the Corresponding Decapeptide1

Olivier Michielin, Vincent Zoete, Pedro Romero, 2007, The Journal of Immunology.

SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules

Olivier Michielin, Vincent Zoete, Antoine Daina, 2019, Nucleic Acids Res..

Drug Design Workshop: A Web-Based Educational Tool To Introduce Computer-Aided Drug Design to the General Public

Marie-Claude Blatter, Ioannis Xenarios, Olivier Michielin, 2017 .

Docking, virtual high throughput screening and in silico fragment-based drug design

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2009, Journal of cellular and molecular medicine.

Rational design of indoleamine 2,3-dioxygenase inhibitors.

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2010, Journal of medicinal chemistry.

The Endocrine Disruptor Monoethyl-hexyl-phthalate Is a Selective Peroxisome Proliferator-activated Receptor γ Modulator That Promotes Adipogenesis*

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2007, Journal of Biological Chemistry.

Comparison between computational alanine scanning and per‐residue binding free energy decomposition for protein–protein association using MM‐GBSA: Application to the TCR‐p‐MHC complex

Olivier Michielin, Vincent Zoete, V. Zoete, 2007, Proteins.

How T cell receptors interact with peptide‐MHCs: A multiple steered molecular dynamics study

Olivier Michielin, Vincent Zoete, M. Cuendet, 2011, Proteins.

In vitro biotransformation of imatinib by the tumor expressed CYP1A1 and CYP1B1

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2008, Biopharmaceutics & drug disposition.

Sequence Determinants of a Microtubule Tip Localization Signal (MtLS)*

Olivier Michielin, Vincent Zoete, Anna Akhmanova, 2012, The Journal of Biological Chemistry.

Unique Spectrum of Activity of Prosimian TRIM5α against Exogenous and Endogenous Retroviruses

Olivier Michielin, Amalio Telenti, Vincent Zoete, 2011, Journal of Virology.

Conformational analysis of a stereochemically complete set of cis-enediol peptide analogues.

Olivier Michielin, Vincent Zoete, Martin Karplus, 2002, Journal of the American Chemical Society.

Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.

Olivier Michielin, Vincent Zoete, Ute F. Röhrig, 2015, Journal of medicinal chemistry.

Combined Simulation and Mutagenesis Analyses Reveal the Involvement of Key Residues for Peroxisome Proliferator-activated Receptorα Helix 12 Dynamic Behavior*

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2007, Journal of Biological Chemistry.

Frequent MAGE Mutations in Human Melanoma

Lloyd J. Old, Olivier Michielin, Jedd D. Wolchok, 2010, PloS one.

Binding free energy differences in a TCR-peptide-MHC complex induced by a peptide mutation: a simulation analysis.

Olivier Michielin, Martin Karplus, M. Karplus, 2002, Journal of molecular biology.

TCRep 3D: An Automated In Silico Approach to Study the Structural Properties of TCR Repertoires

Olivier Michielin, Vincent Zoete, Nathalie Rufer, 2011, PloS one.

Use of the FACTS solvation model for protein–ligand docking calculations. Application to EADock

Aurélien Grosdidier, Olivier Michielin, Vincent Zoete, 2010, Journal of molecular recognition : JMR.