A. D. da Silva

发表

Is obesity a major cause of chronic kidney disease?

T. Dwyer, Jiankang Liu, Terry M Dwyer, 2004, Advances in renal replacement therapy.

Dimethyl fumarate preserves left ventricular infarct integrity following myocardial infarction via modulation of cardiac macrophage and fibroblast oxidative metabolism.

Xuan Li, A. Mouton, A. A. da Silva, 2021, Journal of molecular and cellular cardiology.

Obesity, kidney dysfunction and hypertension: mechanistic links

Michael E. Hall, John E. Hall, M. Hall, 2019, Nature Reviews Nephrology.

Targeting immunometabolism during cardiorenal injury: roles of conventional and alternative macrophage metabolic fuels

A. Mouton, J. D. do Carmo, J. Hall, 2023, Frontiers in Physiology.

Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms.

Michael E. Hall, John E. Hall, M. Hall, 2015, Circulation research.

Role of Endothelin-1 in Blood Pressure Regulation in a Rat Model of Visceral Obesity and Hypertension

A. A. da Silva, J. Kuo, L. Tallam, 2004, Hypertension.

The loss of hepatic PPARα in mice causes hypertension and cardiovascular disease.

T. Hinds, D. Stec, Lucy C Taylor, 2023, American journal of physiology. Regulatory, integrative and comparative physiology.

Role of Hyperinsulinemia and Insulin Resistance in Hypertension: Metabolic Syndrome Revisited.

Xuan Li, A. Mouton, A. A. da Silva, 2020, The Canadian journal of cardiology.

Obesity, hypertension, and chronic kidney disease

Michael E. Hall, L. Juncos, A. A. da Silva, 2014, International journal of nephrology and renovascular disease.

Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins*

Grant Smith, D. Stec, A. A. da Silva, 2010, The Journal of Biological Chemistry.

Hypertension: physiology and pathophysiology.

Michael E. Hall, Michael E Hall, J. Granger, 2012, Comprehensive Physiology.

LPS tolerance prevents anxiety-like behavior and amygdala inflammation of high-fat-fed dams’ adolescent offspring

Arthur Rocha-Gomes, T. R. Riul, A. A. da Silva, 2021, Behavioural Brain Research.

Obesity, kidney dysfunction and inflammation: interactions in hypertension.

John E. Hall, Xuan Li, A. Mouton, 2020, Cardiovascular research.

Restoration of Cardiac Function After Myocardial Infarction by Long-Term Activation of the CNS Leptin-Melanocortin System

Xuan Li, R. Harmancey, A. A. da Silva, 2021, JACC. Basic to translational science.

Transient receptor potential cation channel 6 contributes to kidney injury induced by diabetes and hypertension

Yiling Fu, Xuan Li, A. Mouton, 2021, American journal of physiology. Renal physiology.

Obesity-Induced Hypertension: Brain Signaling Pathways

A. A. da Silva, J. D. do Carmo, Zhen Wang, 2016, Current Hypertension Reports.

Control of Blood Pressure, Appetite, and Glucose by Leptin in Mice Lacking Leptin Receptors in Proopiomelanocortin Neurons

John E. Hall, Shuying Lin, Z. Cai, 2011, Hypertension.

Impact of obesity on renal structure and function in the presence and absence of hypertension: evidence from melanocortin-4 receptor-deficient mice.

A. A. da Silva, J. D. do Carmo, L. Tallam, 2009, American journal of physiology. Regulatory, integrative and comparative physiology.

Obesity-associated hypertension and kidney disease

John E. Hall, Jiankang Liu, A. A. da Silva, 2003, Current opinion in nephrology and hypertension.

Endogenous Melanocortin System Activity Contributes to the Elevated Arterial Pressure in Spontaneously Hypertensive Rats

A. A. da Silva, J. D. do Carmo, B. Kanyicska, 2008, Hypertension.

Role of Hypothalamic Melanocortin 3/4-Receptors in Mediating Chronic Cardiovascular, Renal, and Metabolic Actions of Leptin

A. A. da Silva, J. Kuo, J. Hall, 2004, Hypertension.

Role of Adrenergic Activity in Pressor Responses to Chronic Melanocortin Receptor Activation

J. Kuo, L. Tallam, J. Hall, 2004, Hypertension.

Regulation of Blood Pressure, Appetite, and Glucose by CNS Melanocortin System in Hyperandrogenemic Female SHR.

A. A. da Silva, J. D. do Carmo, Sydney P. Moak, 2016, American journal of hypertension.

Aerobic Exercise Training Reduces Atherogenesis Induced by Low-Sodium Diet in LDL Receptor Knockout Mice

S. Catanozi, M. Passarelli, A. A. da Silva, 2022, Antioxidants.

Impact of leptin deficiency compared to neuronal specific leptin receptor deletion on cardiometabolic regulation.

John E. Hall, A. A. da Silva, J. D. do Carmo, 2019, American journal of physiology. Regulatory, integrative and comparative physiology.

Role of autonomic nervous system in chronic CNS-mediated antidiabetic action of leptin.

A. A. da Silva, J. D. do Carmo, Sydney P. Moak, 2017, American journal of physiology. Endocrinology and metabolism.

Role of leptin and central nervous system melanocortins in obesity hypertension

A. A. da Silva, J. Carmo, J. Hall, 2013, Current opinion in nephrology and hypertension.

Mechanisms of Synergistic Interactions of Diabetes and Hypertension in Chronic Kidney Disease: Role of Mitochondrial Dysfunction and ER Stress

John E. Hall, Yiling Fu, A. A. da Silva, 2020, Current Hypertension Reports.

High-Salt Diet in the Pre- and Postweaning Periods Leads to Amygdala Oxidative Stress and Changes in Locomotion and Anxiety-Like Behaviors of Male Wistar Rats

C. Reichetzeder, Arthur Rocha-Gomes, T. R. Riul, 2022, Frontiers in Behavioral Neuroscience.

Central Nervous System Actions of Leptin Improve Cardiac Function After Ischemia–Reperfusion: Roles of Sympathetic Innervation and Sex Differences

Xuan Li, A. Mouton, A. A. da Silva, 2022, Journal of the American Heart Association.

Inhibition of soluble epoxide hydrolase reduces food intake and increases metabolic rate in obese mice.

J. Hall, A. A. da Silva, J. D. do Carmo, 2012, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Aldosterone Antagonism Attenuates Obesity-Induced Hypertension and Glomerular Hyperfiltration

A. A. da Silva, R. D. de Paula, J. Hall, 2004, Hypertension.

Control of respiratory and cardiovascular functions by leptin.

J. Menani, D. Colombari, D. Zoccal, 2015, Life sciences.

Leptin into the ventrolateral medulla facilitates chemorespiratory response in leptin‐deficient (ob/ob) mice

J. Menani, E. Colombari, W. I. Furuya, 2014, Acta physiologica.

Enhanced blood pressure and appetite responses to chronic central melanocortin-3/4 receptor blockade in dietary-induced obesity

A. A. da Silva, J. Hall, J. Dubinion, 2010, Journal of hypertension.

A Functional Melanocortin System May Be Required for Chronic CNS-Mediated Antidiabetic and Cardiovascular Actions of Leptin

A. A. da Silva, J. D. do Carmo, L. Tallam, 2009, Diabetes.

Control of appetite, blood glucose, and blood pressure during melanocortin-4 receptor activation in normoglycemic and diabetic NPY-deficient mice.

A. A. da Silva, J. D. do Carmo, J. Hall, 2018, American journal of physiology. Regulatory, integrative and comparative physiology.

Systemic But Not Central Nervous System Nitric Oxide Synthase Inhibition Exacerbates the Hypertensive Effects of Chronic Melanocortin-3/4 Receptor Activation

M. Bassi, A. A. da Silva, J. D. do Carmo, 2011, Hypertension.

COVID‐19: Understanding the impact of anti‐hypertensive drugs and hydroxychloroquine on the ACE1 and ACE2 in lung and adipose tissue in SHR and WKY rats

M. A. Peres, L. Furukawa, M. K. Uchiyama, 2023, Physiological reports.

Maternal high-sodium intake alters the responsiveness of the renin-angiotensin system in adult offspring.

J. Heimann, I. Oliveira, L. Furukawa, 2012, Life sciences.

Role of the brain melanocortins in blood pressure regulation.

A. A. da Silva, J. D. do Carmo, Zhen Wang, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Regulation of Blood Pressure, Appetite, and Glucose by Leptin After Inactivation of Insulin Receptor Substrate 2 Signaling in the Entire Brain or in Proopiomelanocortin Neurons

John E. Hall, A. A. da Silva, J. D. do Carmo, 2016, Hypertension.

Brain-mediated antidiabetic, anorexic, and cardiovascular actions of leptin require melanocortin-4 receptor signaling.

J. Granger, A. A. da Silva, J. D. do Carmo, 2015, Journal of neurophysiology.

Differential control of metabolic and cardiovascular functions by melanocortin-4 receptors in proopiomelanocortin neurons.

A. A. da Silva, J. D. do Carmo, J. Rushing, 2013, American journal of physiology. Regulatory, integrative and comparative physiology.

Activation of the central melanocortin system contributes to the increased arterial pressure in obese Zucker rats.

J. D. do Carmo, J. Rushing, J. Hall, 2012, American journal of physiology. Regulatory, integrative and comparative physiology.

Melanocortin-4 Receptor Mediates Chronic Cardiovascular and Metabolic Actions of Leptin

A. A. da Silva, L. Tallam, J. Hall, 2006, Hypertension.

Melanocortin-4 Receptor–Deficient Mice Are Not Hypertensive or Salt-Sensitive Despite Obesity, Hyperinsulinemia, and Hyperleptinemia

D. Stec, L. Tallam, M. Willis, 2005, Hypertension.

Chronic central nervous system hyperinsulinemia and regulation of arterial pressure and food intake

Jiankang Liu, A. A. da Silva, L. Tallam, 2006, Journal of hypertension.

Chronic CNS-mediated cardiometabolic actions of leptin: potential role of sex differences.

A. A. da Silva, J. D. do Carmo, F. Spradley, 2020, American journal of physiology. Regulatory, integrative and comparative physiology.

CNS Regulation of Glucose Homeostasis: Role of the Leptin-Melanocortin System

A. A. da Silva, J. D. do Carmo, J. Hall, 2020, Current Diabetes Reports.

Cafeteria diet administered from lactation to adulthood promotes a change in risperidone sensitivity on anxiety, locomotion, memory, and social interaction of Wistar rats

Arthur Rocha-Gomes, T. R. Riul, A. A. da Silva, 2020, Physiology & Behavior.

Increased sleep time and reduced energy expenditure contribute to obesity after ovariectomy and a high fat diet

A. A. da Silva, J. D. do Carmo, Sydney P. Moak, 2018, Life sciences.

In search for potential antidiabetic compounds from natural sources: docking, synthesis and biological screening of small molecules from Lycium spp. (Goji)

L. Walker, Shabana I. Khan, I. Khan, 2019, Heliyon.

Role of hindbrain melanocortin-4 receptor activity in controlling cardiovascular and metabolic functions in spontaneously hypertensive rats

A. A. da Silva, J. D. do Carmo, J. Hall, 2015, Journal of hypertension.

Chronic Central Nervous System MC3/4R Blockade Attenuates Hypertension Induced by Nitric Oxide Synthase Inhibition but Not by Angiotensin II Infusion

M. Bassi, A. A. da Silva, J. D. do Carmo, 2015, Hypertension.

Does Obesity Induce Resistance to the Long-Term Cardiovascular and Metabolic Actions of Melanocortin 3/4 Receptor Activation?

Jiankang Liu, A. A. da Silva, J. Kuo, 2006, Hypertension.

Cardiovascular, Renal, and Metabolic Responses to Chronic Central Administration of Agouti-Related Peptide

A. A. da Silva, J. Kuo, L. Tallam, 2004, Hypertension.

Temporal changes in glucose metabolism reflect polarization in resident and monocyte-derived macrophages after myocardial infarction

J. McLean, S. Sherrod, S. Codreanu, 2023, Frontiers in Cardiovascular Medicine.

Role of melanocortin 4 receptor in hypertension induced by chronic intermittent hypoxia

A. A. da Silva, J. D. do Carmo, F. Spradley, 2019, Acta physiologica.

Transient receptor potential cation channel 6 (TRPC6) deficiency leads to increased body weight and metabolic dysfunction.

Yiling Fu, Xuan Li, A. Mouton, 2022, American journal of physiology. Regulatory, integrative and comparative physiology.

Direct Cardiac Actions of Sodium-Glucose Cotransporter 2 Inhibition Improve Mitochondrial Function and Attenuate Oxidative Stress in Pressure Overload-Induced Heart Failure

Michael E. Hall, Xuan Li, M. Hall, 2022, Frontiers in Cardiovascular Medicine.

Inhibitor &kgr;B Kinase 2 Is a Myosin Light Chain Kinase in Vascular Smooth Muscle

Michael C. Ostrowski, S. Rajagopalan, M. Ostrowski, 2013, Circulation research.

Interaction of Obesity and Hypertension on Cardiac Metabolic Remodeling and Survival Following Myocardial Infarction

Michael E. Hall, Xuan Li, A. Mouton, 2021, Journal of the American Heart Association.

Role of SOCS3 in POMC neurons in metabolic and cardiovascular regulation.

A. A. da Silva, J. D. do Carmo, Zhen Wang, 2019, American journal of physiology. Regulatory, integrative and comparative physiology.

Direct Cardiac Actions of the Sodium Glucose Co‐Transporter 2 Inhibitor Empagliflozin Improve Myocardial Oxidative Phosphorylation and Attenuate Pressure‐Overload Heart Failure

Michael E. Hall, Qingguo Lu, Xuan Li, 2021, Journal of the American Heart Association.

Chronic antidiabetic and cardiovascular actions of leptin: role of CNS and increased adrenergic activity.

Jiankang Liu, A. A. da Silva, L. Tallam, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Synergistic Interaction of Hypertension and Diabetes in Promoting Kidney Injury and the Role of Endoplasmic Reticulum Stress

Xinchun Zhou, J. Williams, A. A. da Silva, 2017, Hypertension.

Chronic central leptin infusion restores cardiac sympathetic-vagal balance and baroreflex sensitivity in diabetic rats.

A. A. da Silva, J. D. do Carmo, J. Hall, 2008, American journal of physiology. Heart and circulatory physiology.

Melanocortin-4 Receptor–Deficient Mice Are Not Hypertensive or Salt-Sensitive Despite Obesity, Hyperinsulinemia, and Hyperleptinemia

D. Stec, A. A. da Silva, L. Tallam, 2005 .

Renin-angiotensin system function and blood pressure in adult rats after perinatal salt overload.

A. A. da Silva, J. Heimann, I. B. de Oliveira, 2003, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Role of Shp2 in forebrain neurons in regulating metabolic and cardiovascular functions and responses to leptin

A. A. da Silva, J. D. do Carmo, Mark T Davis, 2013, International Journal of Obesity.

Chronic blood pressure and appetite responses to central leptin infusion in rats fed a high fat diet

A. A. da Silva, J. Hall, J. Dubinion, 2011, Journal of hypertension.

Role of Proopiomelanocortin Neuron Stat3 in Regulating Arterial Pressure and Mediating the Chronic Effects of Leptin

Ahmad Adi, John H Dubinion, Jussara M do Carmo, 2013, Hypertension.

Leptin reverses hyperglycemia and hyperphagia in insulin deficient diabetic rats by pituitary-independent central nervous system actions

A. A. da Silva, J. D. do Carmo, J. Hall, 2017, PloS one.

The brain melanocortin system, sympathetic control, and obesity hypertension.

J. D. do Carmo, Zhen Wang, J. Hall, 2014, Physiology.

Obesity, kidney dysfunction and hypertension: mechanistic links

Michael E. Hall, J. D. do Carmo, Zhen Wang, 2019, Nature Reviews Nephrology.

Sex differences in the impact of parental obesity on offspring cardiac SIRT3 expression, mitochondrial efficiency and diastolic function early in life.

Xuan Li, A. Mouton, A. A. da Silva, 2021, American journal of physiology. Heart and circulatory physiology.

High-intensity interval training improves long-term memory and increases hippocampal antioxidant activity and BDNF levels in ovariectomized Wistar rats

Arthur Rocha-Gomes, T. R. Riul, C. P. Bastos, 2023, Behavioural Brain Research.

Neuronal Suppressor of Cytokine Signaling 3: Role in Modulating Chronic Metabolic and Cardiovascular Effects of Leptin

Michael W. Hankins, John E. Hall, H. Drummond, 2018, Hypertension.

Shp2 signaling in POMC neurons is important for leptin's actions on blood pressure, energy balance, and glucose regulation.

B. Lowell, J. Elmquist, A. A. da Silva, 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

Impact of leptin deficiency on male tibia and vertebral body 3D bone architecture independent of changes in body weight

J. D. do Carmo, A. D. da Silva, N. Aberdein, 2023, Physiological reports.