K. Watanabe

发表

Pharmacological features of non-adrenergic non-cholinergic (NANC) relaxation induced by electrical vagal stimulation in isolated mouse stomach.

Y. Kiyota, S. Yano, M. Yamamoto, 1995, Japanese journal of pharmacology.

Potent inhibitors of acyl-CoA:cholesterol acyltransferase. 2. Structure-activity relationships of novel N-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)amides.

H. Tanaka, K. Kataoka, K. Watanabe, 1996, Journal of medicinal chemistry.

[Effect of moxisylyte on the lower urinary tracts (2). Effect on the urethra in anesthetized dogs].

H. Ohnishi, Y. Hayashi, K. Ikeda, 1991, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Comparative effects of cimetidine and famotidine on the vagally stimulated acid secretion in the isolated mouse whole stomach.

K. Watanabe, S. Yano, M. Yamamoto, 1993, Japanese journal of pharmacology.

Cytochrome P-450 isozymes involved in the oxidative metabolism of delta 9-tetrahydrocannabinol by liver microsomes of adult female rats.

I. Yamamoto, S. Imaoka, Y. Funae, 1992, Drug metabolism and disposition: the biological fate of chemicals.

3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-induced egr-1 mRNA in rat brain: pharmacological manipulation.

K. Hashimoto, M. Iyo, Y. Minabe, 2000, European journal of pharmacology.

Inhibition of anandamide amidase activity in mouse brain microsomes by cannabinoids.

I. Yamamoto, Kazuhito Watanabe, T. Matsunaga, 1996, Biological & pharmaceutical bulletin.

A carbonyl reductase-catalyzing reduction of N3-phenacyluridine in rabbit liver.

I. Yamamoto, T. Matsunaga, T. Kimura, 2000, Biological and Pharmaceutical Bulletin.

Plasma estradiol 17-sulfate and 2-hydroxyestradiol 17-sulfate levels and their metabolic clearance rates in rats.

K. Takanashi, I. Yoshizawa, K. Watanabe, 1989, Journal of steroid biochemistry.

Tissue distribution of estradiol 17-sulfate 2- and 4-hydroxylation enzymes in the rat.

K. Watanabe, I. Yoshizawa, K. Watanabe, 1987, Journal of pharmacobio-dynamics.

An induction effect of phenobarbital on rat liver microsomal 4-hydroxylation of estradiol 17-sulfate.

K. Watanabe, I. Yoshizawa, R. Kimura, 1984, Journal of pharmacobio-dynamics.

Evidence for 4-hydroxylation of estradiol 17-sulfate by rat liver microsomes (clinical analysis on steroids. XXIX).

I. Yoshizawa, R. Kimura, K. Watanabe, 1984, Chemical & pharmaceutical bulletin.

Preparation and high-performance liquid chromatographic determination of guaiacol estrogen 17 beta-conjugates: the enzymatic O-methylation products of 2-hydroxyestradiol 17 beta-conjugates (clinical analysis on steroids. XXII).

I. Yoshizawa, K. Watanabe, 1982, Chemical & pharmaceutical bulletin.

Estradiol 17 beta-sulfate as a substrate for 2-hydroxylation enzyme of rat liver microsomes (clinical analysis on steroids. XX).

K. Watanabe, I. Yoshizawa, K. Watanabe, 1982, Journal of pharmacobio-dynamics.

Clinical analysis of steroids. XXV. Assay of estradiol 17-sulfate 2-hydroxylase activity by high-performance liquid chromatography.

K. Watanabe, I. Yoshizawa, K. Watanabe, 1983, Journal of chromatography.

Effects of two cannabinoids on hepatic microsomal cytochrome P-450.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1986, Journal of pharmacobio-dynamics.

Metabolism of delta 9-tetrahydrocannabinol by cytochrome P450 isozymes purified from hepatic microsomes of monkeys.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1995, Life sciences.

Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide.

L. Lou, K. Watanabe, S. Greene, 1995, Biochemical pharmacology.

Antiulcer activities of glycyrrhetinic acid derivatives in experimental gastric lesion models.

T. Mori, K. Hirabayashi, K. Watanabe, 1989, Chemical & pharmaceutical bulletin.

A cytochrome P450 isozyme having aldehyde oxygenase activity plays a major role in metabolizing cannabinoids by mouse hepatic microsomes.

I. Yamamoto, S. Narimatsu, T. Matsunaga, 1993, Biochemical pharmacology.

The effect of the acute administration of various selective 5-HT receptor antagonists on focal hippocampal seizures in freely-moving rats.

Y. Minabe, C. Ashby, K. Watanabe, 2000, European journal of pharmacology.

Effects of hirsutine, an antihypertensive indole alkaloid from Uncaria rhynchophylla, on intracellular calcium in rat thoracic aorta.

K. Watanabe, N. Aimi, S. Yano, 1992, Life sciences.

The properties of UDP-glucuronyltransferase for cannabinoids in rat liver microsomes.

I. Yamamoto, K. Oguri, H. Yoshimura, 1983, Journal of pharmacobio-dynamics.

UDP-glucuronyltransferase activities of rabbit liver microsomes for cannabinoids.

I. Yamamoto, K. Oguri, H. Yoshimura, 1980, Journal of Pharmacobio-Dynamics.

Synthesis of delta 8-tetrahydrocannabinol glucuronide and sulfate, and their metabolic disposition in rats.

K. Oguri, H. Yoshimura, K. Watanabe, 1979, Chemical & pharmaceutical bulletin.

Sex difference in hepatic microsomal aldehyde oxygenase activity in different strains of mice.

I. Yamamoto, S. Narimatsu, T. Matsunaga, 1992, Research communications in chemical pathology and pharmacology.

Effect of acute administration of various 5-HT receptor agonists on focal hippocampal seizures in freely moving rats.

Y. Minabe, C. Ashby, C R Ashby, 1998, European journal of pharmacology.

Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells.

I. Yamamoto, Kazuhito Watanabe, K. Waku, 1997, Journal of biochemistry.

Centrally mediated inhibitory effect of 5-[2-(diethylamino)ethyl]amino-5,11-dihydro[1]benzoxepino[3,4- b]pyridine trihydrochloride (KW-5805) on gastric acid secretion in rats.

N. Yamada, M. Mizuno, S. Yano, 1990, Japanese journal of pharmacology.

Studies on relationships between chemical structure and beta-blocking potency of bopindolol and its two metabolites.

M. Ishiguro, Y. Hosohata, N. Takatsu, 1998, Life sciences.

Achatin-I, an endogenous neuroexcitatory tetrapeptide from Achatina fulica Férussac containing a D-amino acid residue.

K. Funase, T. Iwashita, H. Minakata, 1989, Biochemical and biophysical research communications.

Diels-Alder reactions of nitro-2(1H)-pyridones with 2,3-dimethyl-1,3-butadiene.

Y. Nishiuchi, K. Watanabe, H. Hongo, 2001, Chemical & pharmaceutical bulletin.

Thyrotropin-releasing hormone (TRH)-induced gastric acid secretion in aging rats.

K. Watanabe, H. Watanabe, M. Maeda-Hagiwara, 1984, Japanese journal of pharmacology.

A rat model of neurolathyrism: repeated injection of L-β-ODAP induces the paraparesis of the hind legs

K. Watanabe, K. Igarashi, T. Kusama, 2005, Amino Acids.

Oxygenation mechanism in conversion of aldehyde to carboxylic acid catalyzed by a cytochrome P-450 isozyme.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1991, The Journal of biological chemistry.

Inhibitory action of synthetic proteinase inhibitors and substrates on the chemotaxis of rat polymorphonuclear leukocytes in vitro.

H. Nakagawa, K. Sato, K. Watanabe, 1988, Journal of pharmacobio-dynamics.

Properties of rotational behaviour produced by methylxanthine derivatives in mice with unilateral striatal 6-hydroxydopamine-induced lesions.

H. Watanabe, K. Watanabe, M. Ikeda, 1981, Journal of pharmacobio-dynamics.

Penetrable and impenetrable anions into the GABA-activated chloride channel on the postsynaptic neuromembrane of an identifiable giant neurone of an African giant snail (Achatina fulica Férussac).

H. Takeuchi, K. Watanabe, H. Tamura, 1978, Comparative biochemistry and physiology. C: Comparative pharmacology.

Comparative effects of simvastatin (MK-733) and pravastatin (CS-514) on hypercholesterolemia induced by cholesterol feeding in rabbits.

K. Kitani, K. Watanabe, T. Kamei, 1990, Biochimica et biophysica acta.

Ca2+ channel blocking effects of hirsutine, an indole alkaloid from Uncaria genus, in the isolated rat aorta.

K. Watanabe, N. Aimi, S. Yano, 1991, Planta medica.

Preventive effect of MK-733 (simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits.

K. Watanabe, T. Takahashi, T. Kamei, 1989, Japanese journal of pharmacology.

Effect of simvastatin (MK-733) on plasma triacylglycerol levels in rats.

K. Watanabe, T. Kamei, F. Ishida, 1991, Biochemical Pharmacology.

Synthesis and pharmacological activity of O-(5-isoxazolyl)-L-serine.

T. Ishikawa, T. Kusama, T. Sekine, 2000, Chemical & pharmaceutical bulletin.

Carvedilol enhances atrial and brain natriuretic peptide mRNA expression and release in rat heart.

M. Kodama, Y. Aizawa, K. Watanabe, 2000, Journal of cardiovascular pharmacology.

Involvement of CYP2C in the metabolism of cannabinoids by human hepatic microsomes from an old woman.

I. Yamamoto, Y. Funae, T. Matsunaga, 1995, Biological & pharmaceutical bulletin.

Nafamostat is hydrolysed by human liver cytosolic long-chain acyl-CoA hydrolase

S. Yamaori, I. Yamamoto, Kazuhito Watanabe, 2007, Xenobiotica; the fate of foreign compounds in biological systems.

Cytochrome P450 isozymes catalyzing the hepatic microsomal oxidation of 9-anthraldehyde to 9-anthracene carboxylic acid in adult male rats.

I. Yamamoto, S. Imaoka, Y. Funae, 1993, Biological & pharmaceutical bulletin.

Fluorometric assay of microsomal aldehyde oxygenase activity: 9-anthraldehyde as a substrate.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1991, Analytical biochemistry.

Cytochrome P-450 isozymes in metabolic activation of delta 9-tetrahydrocannabinol by rat liver microsomes.

I. Yamamoto, S. Imaoka, Y. Funae, 1990, Drug metabolism and disposition: the biological fate of chemicals.

Inhibition of hepatic microsomal cytochrome P450 by cannabidiol in adult male rats.

I. Yamamoto, S. Imaoka, Y. Funae, 1990, Chemical and pharmaceutical bulletin.

Hepatic microsomal oxygenation of aldehydes to carboxylic acids.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1990, Biochemical and Biophysical Research Communications - BBRC.

Oxygenation mechanism in the oxidation of xenobiotic aldehyde to carboxylic acid by mouse hepatic microsomes.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1988, Biochemical and biophysical research communications.

Comparison in mice of pharmacological effects of delta 8-tetrahydrocannabinol and its metabolites oxidized at 11-position.

I. Yamamoto, K. Oguri, H. Yoshimura, 1980, European journal of pharmacology.

Mechanism of hepatic microsomal oxidation of 11-hydroxy-delta 8-tetrahydrocannabinol to 11-oxo-delta 8-tetrahydrocannabinol. Evidence for hydration of the aldehyde formed.

I. Yamamoto, S. Narimatsu, T. Matsunaga, 1992, Journal of pharmacobio-dynamics.

Mechanism for inhibitory effect of cannabidiol on microsomal testosterone oxidation in male rat liver.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1988, Drug metabolism and disposition: the biological fate of chemicals.

Change in hypothermia and catalepsy induced by cannabinoids or morphine in mice tolerant to these substances.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1987, European journal of pharmacology.

In vitro and in vivo interactions of delta 8-tetra-hydrocannabinol and its metabolites with hepatic microsomal drug metabolizing enzyme systems of mice.

I. Yamamoto, K. Oguri, H. Yoshimura, 1981, Journal of pharmacobio-dynamics.

Major cytochrome P450 enzyme responsible for oxidation of secondary alcohols to the corresponding ketones in mouse hepatic microsomes. Oxidation of 7-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Recent advances in the metabolism of cannabinoids.

I. Yamamoto, Kazuhito Watanabe, S. Narimatsu, 1995, The international journal of biochemistry & cell biology.

Inhibitory effect of cannabidiol hydroxy-quinone, an oxidative product of cannabidiol, on the hepatic microsomal drug-metabolizing enzymes of mice.

I. Yamamoto, N. Usami, H. Yoshimura, 1991, Journal of pharmacobio-dynamics.

Mouse hepatic microsomal oxidation of aliphatic aldehydes (C8 to C11) to carboxylic acids.

I. Yamamoto, S. Narimatsu, T. Matsunaga, 1992, Biochemical and biophysical research communications.

Metabolic disposition of delta 8-tetrahydrocannabinol and its active metabolites, 11-hydroxy-delta 8-tetrahydrocannabinol and 11-oxo-delta 8-tetrahydrocannabinol, in mice.

I. Yamamoto, K. Oguri, H. Yoshimura, 1981, Drug metabolism and disposition: the biological fate of chemicals.

Protective role of vanilloid receptor type 1 in HCl‐induced gastric mucosal lesions in rats

G. Michael, J. Priestley, H. Yamamoto, 2004, Scandinavian journal of gastroenterology.

Effects of pretreatment with cytochrome P-450 inducers, especially phenobarbital on triphenyltin metabolism and toxicity in hamsters.

K. Watanabe, H. Matsui, S. Ohhira, 1999, Toxicology.

Effects of vanilloid receptor agonists and antagonists on gastric antral ulcers in rats.

H. Yamamoto, T. Murayama, S. Horie, 2001, European journal of pharmacology.

The role of capsaicin-sensitive afferent nerves in protective effect of capsaicin against absolute ethanol-induced gastric lesions in rats.

K. Watanabe, S. Yano, M. Uchida, 1991, Japanese journal of pharmacology.

Neurogenic stimulation of gastric acid secretion by the Na+, K(+)-ATPase inhibitor ouabain in mouse isolated stomach.

S. Yano, T. Maruyama, S. Horie, 1996, General pharmacology.

Transplacental effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on brain dopaminergic neurons in the mouse

S. Nagao, H. Takahashi, Hisahide Takahashi, 1989, Acta Neuropathologica.

Difference in epoxides formation and their further metabolism between delta 9- and delta 8-tetrahydrocannabinols by human liver microsomes.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1984, Journal of pharmacobio-dynamics.

Human liver microsomal oxidation of delta 8-tetrahydrocannabinol.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1983, Chemical & pharmaceutical bulletin.

STUDIES ON THE DRUGS FOR PEPTIC ULCER. A RELIABLE METHOD FOR PRODUCING STRESS ULCER IN RATS.

K TAKAGI, Y KASUYA, K WATANABE, 1964, Chemical & pharmaceutical bulletin.

Presence of TAN (tonically autoactive neuron) and its two analogous neurons, located in the right parietal ganglion of the suboesophageal ganglia of an African giant snail (Achatina fulica Ferussac). Morphological and electrophysiological studies.

H. Takeuchi, T. Goto, K. Watanabe, 1986, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Pharmacological characteristics of three silent giant neurons, v-LPSN, v-1-VOrN and v-VLN, identified on the ventral surface in the left parietal and the visceral ganglia of the suboesophageal ganglia of an African giant snail (Achatina fulica Férussac).

H. Takeuchi, K. Watanabe, T. Matsuoka, 1985, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

Pharmacological properties of a new anti-inflammatory compound, alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolacto ne (KME-4), and its inhibitory effects on prostaglandin synthetase and 5-lipoxygenase.

I. Katsumi, T. Yamashita, K. Hosoe, 1984, Japanese journal of pharmacology.

[Effect of cilnidipine on renal function in SHR and endothelin-induced renal dysfunction].

M. Hosono, K. Watanabe, Y. Hayashi, 1996, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Anandamide, an endogenous cannabinoid receptor ligand, also interacts with 5-hydroxytryptamine (5-HT) receptor.

I. Yamamoto, Kazuhito Watanabe, T. Ohta, 1998, Biological & pharmaceutical bulletin.

Stimulatory effects of centrally injected kappa-opioid receptor agonists on gastric acid secretion in urethane-anesthetized rats.

K. Watanabe, T. Murayama, S. Horie, 2001, European journal of pharmacology.

Metabolism of a novel hypnotic, N3-phenacyluridine, and hypnotic and sedative activities of its enantiomer metabolites in mouse

I. Yamamoto, K. Watanabe, T. Kimura, 2000, Xenobiotica; the fate of foreign compounds in biological systems.

Effects of pretreatment with SKF-525A on triphenyltin metabolism and toxicity in mice.

K. Watanabe, H. Matsui, S. Ohhira, 2000, Toxicology letters.

Effect of alpha-(3,5-di-tert-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), a new anti-inflammatory drug, on the established adjuvant arthritis in rats.

K. Watanabe, T. Yamashita, K. Hosoe, 1986, Japanese journal of pharmacology.

Effects of drugs on behavior, heart rate and catecholamine levels in thiamine-deficient rats.

H. Iwata, M. Ohashi, T. Nishikawa, 1969, European journal of pharmacology.

Self-catalyzed inactivation of cytochrome P-450 during microsomal metabolism of cannabidiol.

I. Yamamoto, Kazuhito Watanabe, S. Narimatsu, 1987, Biochemical pharmacology.

Pharmacological activities in the mouse of delta 9-tetrahydrocannabinol metabolites oxidized at the 8-position.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1985, Chemical & pharmaceutical bulletin.

9 alpha, 10 alpha-epoxyhexahydrocannabinol formation from delta 9-tetrahydrocannabinol by liver microsomes of phenobarbital-treated mice and its pharmacological activities in mice.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1983, Journal of pharmacobio-dynamics.

Bromocriptine inhibits 2-deoxy-D-glucose-stimulated gastric acid secretion in the rat.

K. Watanabe, M. Maeda-Hagiwara, K. Watanabe, 1983, European journal of pharmacology.

Ca2+ channel‐blocking effect of the yohimbine derivatives, 14β‐benzoyloxyyohimbine and 14β‐p‐nitrobenzoyloxyyohimbine

K. Watanabe, N. Aimi, S. Yano, 1987 .

gamma-butyrolactone enhances the activity of GABA in the gastric acid secretion of anesthetized rats.

K. Watanabe, Y. Goto, H. Watanabe, 1983, Japanese journal of pharmacology.

Pharmacological properties of codeine-7,8-oxide (codeine epoxide), a new metabolite of codeine.

N. Miyata, M. Hirobe, I. Takayanagi, 1982, Japanese journal of pharmacology.

Stimulatory effect of centrally injected capsaicin, an agonist of vanilloid receptors, on gastric acid secretion in rats.

K. Watanabe, T. Murayama, S. Horie, 2001, European journal of pharmacology.

Synthesis and analgesic activity of morphine-7,8-oxide and heroin-7,8-oxide.

N. Miyata, M. Hirobe, K. Watanabe, 1980, Chemical & pharmaceutical bulletin.

Codeine-7,8-oxide (4,5 alpha-epoxy-7 beta, 8 beta-epoxy-3-methoxy-17-methyl-morphinan-6 alpha -ol: identification as a metabolite of codeine.

N. Miyata, M. Hirobe, K. Uba, 1980, Chemical & pharmaceutical bulletin.

[Effects of oxybutynin hydrochloride on the urinary bladder and urethra in in situ preparations].

K. Watanabe, T. Kasama, K. Mayuzumi, 1986, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

In vivo effects of tetrahydrocannabinols and their eight monooxygenated metabolites of the hepatic microsomal drug-metabolizing enzyme systems of mice.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1987, Journal of pharmacobio-dynamics.

Inhibitory effect of cilnidipine on vascular sympathetic neurotransmission and subsequent vasoconstriction in spontaneously hypertensive rats.

H. Ohnishi, M. Hosono, H. Kato, 1995, Japanese journal of pharmacology.

Gastric acid secretion is augmented by the replacement of extracellular Na+ with K+ or other ions.

T. Urushidani, T. Nagao, K. Akagi, 1998, Japanese journal of pharmacology.

Sex difference in the oxidative metabolism of delta 9-tetrahydrocannabinol in the rat.

I. Yamamoto, S. Narimatsu, H. Yoshimura, 1991, Biochemical pharmacology.

Stimulatory effect of pentobarbital and some anesthetics on gastric secretion in the continuously perfused stomach in rats under urethane anesthesia.

S. Yano, W. Lin, K. Watanabe, 1987, Japanese journal of pharmacology.

Slow association of positively charged Ca2+ channel antagonist amlodipine to dihydropyridine receptor sites in rat brain membranes.

Y. Qu, K. Watanabe, K. Sugiyama, 1996, General pharmacology.

Involvement of CGRP, substance P and blood circulation in aggravating mechanism of absolute ethanol-induced antral lesions by capsaicin treatment in rats.

K. Watanabe, S. Yano, M. Uchida, 1993, Japanese journal of pharmacology.

Aggravation by the capsaicin-treatment of gastric antral ulcer induced by the combination of 2-deoxy-D-glucose, aspirin and ammonia in rats.

K. Watanabe, S. Yano, M. Uchida, 1991, Japanese journal of pharmacology.

Cholinergic/dopaminergic interaction in the rat striatum assessed from drug-induced repetitive oral movements.

N. Koshikawa, T. Saigusa, K. Watanabe, 1992, European journal of pharmacology.

Synthesis of phenanthridones using Diels-Alder reactions of 4-substituted 2(1H)-quinolones acting as dienophiles.

Y. Harigaya, H. Hongo, H. Matsuzaki, 2001, Chemical & pharmaceutical bulletin.

Hypolipidemic effects of NB-598 in dogs.

Y. Sawasaki, Y Sawasaki, K Watanabe, 1991, Atherosclerosis.

Effects of β-ODAP and its biosynthetic precursor on the electrophysiological activity of cloned glutamate receptors.

K. Watanabe, K. Kusama-Eguchi, T. Kusama, 1996, Environmental toxicology and pharmacology.

The involvement of catecholamine in scopolamine-induced locomotor activation and rotational behaviour in mice.

K. Watanabe, H. Watanabe, K. Hagino, 1978, Japanese journal of pharmacology.

Involvement of metabolites in the inhibitory effects of 2-(4-ethyl-1-piperazinyl)-4-phenylquinoline dimaleate (AD-2646), a new quinoline derivative, on gastric acid secretion. A comparison with tricyclic antidepressants.

S. Yano, Y. Kimura, K. Watanabe, 1989, Journal of Pharmacobio-Dynamics.

Morphine inhibits the gastric acid secretion stimulated by 2-deoxy-D-glucose via a central mechanism in anesthetized rats.

K. Watanabe, S. Yano, Y. Minakawa, 1987, European journal of pharmacology.

Quantitative aspect of acid secretion response of isolated bullfrog gastric mucosa preparation: effect of secretagogues and inhibitors.

K. Watanabe, Y. Goto, K. Watanabe, 1975, Japanese journal of pharmacology.

Formation of carbon monoxide during mouse hepatic microsomal oxidative metabolism of cannabidiol; identification and determination.

I. Yamamoto, N. Usami, H. Yoshimura, 1995, Biological & pharmaceutical bulletin.

Purification and characterization of a novel 46.5-kilodalton esterase from mouse hepatic microsomes.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1993, Biochemistry and molecular biology international.

Formation of p-hydroxycocaine from cocaine by hepatic microsomes of animals and its pharmacological effects in mice.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1993, Biological & pharmaceutical bulletin.

Affinity for [3H]iloprost binding sites and cAMP synthesis activity of a 3-oxa-methano prostaglandin I1 analog, SM-10906, in human platelets and endothelial cells.

Y. Hara, T. Yamamoto, T. Nagatomo, 1997, Japanese journal of pharmacology.

Plasma copper levels and their significance in morphine analgesia and tolerance.

H. Iwata, Y. Matsui, K. Watanabe, 1970, European journal of pharmacology.

Synthesis and pharmacological effects in mice of halogenated cannabinol derivatives.

I. Yamamoto, N. Usami, H. Yoshimura, 1995, Chemical & pharmaceutical bulletin.

Synthesis and pharmacological evaluation in mice of halogenated cannabidiol derivatives.

I. Yamamoto, N. Usami, H. Yoshimura, 1999, Chemical & pharmaceutical bulletin.

Synthesis and pharmacological activities in mice of halogenated delta 9-tetrahydrocannabinol derivatives.

I. Yamamoto, N. Usami, H. Yoshimura, 1998, Chemical & pharmaceutical bulletin.

Anti-inflammatory effect of proteinase inhibitors on carrageenin-induced inflammation in rats.

K. Watanabe, K. Shuto, S. Tsurufuji, 1983, Biochemical pharmacology.

Development of tolerance to dopaminergic stimulating effect of theophylline in mice with unilateral striatal 6-hydroxydopamine lesions.

H. Watanabe, K. Watanabe, M. Ikeda, 1982, European journal of pharmacology.

Preparation and pharmacological evaluation of N3-substituted thymidine derivatives as central depressants.

I. Yamamoto, K. Watanabe, T. Kimura, 1993, Chemical & pharmaceutical bulletin.

N3-benzyluridine exerts hypnotic activity in mice.

I. Yamamoto, K. Watanabe, T. Kimura, 1985, Chemical & pharmaceutical bulletin.

Hypnotic action of N3-substituted arabinofuranosyluracils on mice.

I. Yamamoto, T. Kimura, I. Ho, 2001, Chemical & pharmaceutical bulletin.

Anti-inflammatory effect of a selective inhibitor of elastase, cathepsin G and chymotrypsin on carrageenin-induced inflammation in rats.

S. Tsurufuji, H. Nakagawa, M. Kaneko, 1986, Journal of pharmacobio-dynamics.

Effect of proteinase inhibitors having anti-inflammatory activity on gelatinase, elastase and cathepsin G isolated from rat polymorphonuclear leukocytes.

K. Shuto, S. Tsurufuji, M. Suzuki, 1982, Journal of pharmacobio-dynamics.

Proteinase inhibitors suppress the formation of granulation tissue in the carrageenin-induced inflammation in rats.

K. Watanabe, K. Shuto, S. Tsurufuji, 1981, Journal of Pharmacobio-Dynamics.

A novel 5-HT(2) antagonist, sarpogrelate hydrochloride, shows inhibitory effects on both contraction and relaxation mediated by 5-HT receptor subtypes in porcine coronary arteries.

M. Nakazawa, M. Rashid, T. Nagatomo, 2000, Pharmacology.

A non-selective β-blocker, bopindolol, exhibits high affinity to 5-HT1A receptor subtype in rat brain as assayed by competition binding experiments

K. Sasaki, J. Suzuki, Y. Hosohata, 1996 .

Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation.

S. Yano, W. Lin, K. Watanabe, 1988, European journal of pharmacology.

Specific expression of ES46.5K, a novel microsomal esterase, in the mouse liver and its catalytic activity for xenobiotic amide and esters.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1997, Life sciences.

Change of copper concentration in the central nervous system after morphine treatment and effect of copper on morphine analgesia in rats

H. Iwata, K. Watanabe, Y. Matsui, 1971 .

The immunosuppressive effects of trichothecenes and cyclochlorotine on the antibody responses in guinea pigs.

K. Watanabe, J. Koyama, H. Ito, 1982, Journal of pharmacobio-dynamics.

Grouped spike discharges of an identifiable neurone of a snail (Achatina fulica férussac) produced in isotonic foreign anion solutions.

H. Takeuchi, K. Watanabe, H. Tamura, 1978, Comparative biochemistry and physiology. C: Comparative pharmacology.

In vivo metabolism of 11-hydroxy-delta-tetrahydrocannabinol to two carboxylic acids and the effects of SKF 525-A, cobaltous chloride and phenobarbital on their formation in rats.

I. Yamamoto, K. Oguri, H. Yoshimura, 1980, Chemical & pharmaceutical bulletin.

The metabolism of estradiol 17-sulfate by pheochromocytoma tissue.

I. Yoshizawa, S. Nakagawa, S. Kurosawa, 1985, Journal of steroid biochemistry.

[Influence of a muscle relaxant, tizanidine, on gastric acid secretion and gastric ulcer in rats].

H. Watanabe, R. Kanaoka, K. Watanabe, 1983, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Gastric antral ulcers produced by the combined administration of indomethacin with 2-deoxy-D-glucose in the rat.

K. Watanabe, M. Maeda-Hagiwara, K. Watanabe, 1983, European journal of pharmacology.

Relationship between gelatinase secretion and chemotaxis of rat polymorphonuclear leukocytes.

K. Watanabe, H. Nakagawa, K. Sato, 1988, Chemical and pharmaceutical bulletin.

Intracellular alkalinization by NH4Cl increases cytosolic Ca2+ level and tension in the rat aortic smooth muscle.

K. Watanabe, S. Yano, S. Horie, 1995, Life sciences.

Enhancement of phenylephrine-induced contraction in the isolated rat aorta with endothelium by H2O-extract from an Oriental medicinal plant Leonuri herba.

K. Watanabe, T. Murayama, S. Horie, 2001, Japanese journal of pharmacology.

3,4,5-Trimethoxyphenylacetaldehyde, an intermediate metabolite of mescaline, is a substrate for microsomal aldehyde oxygenase in the mouse liver.

I. Yamamoto, T. Matsunaga, H. Yoshimura, 1995, Biological & pharmaceutical bulletin.

Production of an interleukin-8-like chemokine by cytokine-stimulated rat NRK-49F fibroblasts and its suppression by anti-inflammatory steroids.

K. Watanabe, T. Gotoda, H. Nakagawa, 1993, Biochemical Pharmacology.

Inhibitory effect of cilnidipine on pressor response to acute cold stress in spontaneously hypertensive rats.

H. Ohnishi, M. Hosono, H. Kato, 1995, Japanese journal of pharmacology.