L. Wilsie

发表

Discovery of a new role of human resistin in hepatocyte low-density lipoprotein receptor suppression mediated in part by proprotein convertase subtilisin/kexin type 9.

O. Palyha, A. Strack, Larissa C Wilsie, 2012, Journal of the American College of Cardiology.

Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats.

Kenneth K. Wu, Q. Deng, Hong C Shen, 2009, Journal of medicinal chemistry.

Discovery of a biaryl cyclohexene carboxylic acid (MK-6892): a potent and selective high affinity niacin receptor full agonist with reduced flushing profiles in animals as a preclinical candidate.

M. Forrest, Kenneth K. Wu, Q. Deng, 2010, Journal of medicinal chemistry.

Cell surface heparan sulfate proteoglycans contribute to intracellular lipid accumulation in adipocytes

R. Orlando, D. Navaratna, Larissa C. Wilsie, 2005, Lipids in Health and Disease.

Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia[S]

N. Geoghagen, L. Mitnaul, Peggy H. Wong, 2012, Journal of Lipid Research.

Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A.

Hong C Shen, J. Tata, S. Colletti, 2008, Bioorganic & medicinal chemistry letters.

New methodologies for studying lipid synthesis and turnover: looking backwards to enable moving forwards.

M. Cleary, D. Johns, Vinit Shah, 2014, Biochimica et biophysica acta.

DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates.

Dermot F. Reilly, S. Bartz, D. Reilly, 2018, Cell metabolism.

Pyrazole acids as niacin receptor agonists for the treatment of dyslipidemia.

D. Blom, J. Tata, S. Colletti, 2009, Bioorganic & medicinal chemistry letters.

Syndecan-1 mediates internalization of apoE-VLDL through a low density lipoprotein receptor-related protein (LRP)-independent, non-clathrin-mediated pathway

R. Orlando, A. Gonzales, Larissa C. Wilsie, 2006, Lipids in Health and Disease.

The Low Density Lipoprotein Receptor-related Protein Complexes with Cell Surface Heparan Sulfate Proteoglycans to Regulate Proteoglycan-mediated Lipoprotein Catabolism*

R. Orlando, Larissa C. Wilsie, L. Wilsie, 2003, The Journal of Biological Chemistry.

C-terminal Loop Mutations Determine Folding and SecretionProperties of PCSK9

D. Johns, T. Vogt, D. Wisniewski, 2016 .

Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia[S]

N. Geoghagen, L. Mitnaul, Peggy H. Wong, 2012, Journal of Lipid Research.