F. García-García

发表

Dose-response association between physical activity and sedentary time categories on ageing biomarkers

J. Losa-Reyna, L. Rodríguez-Mañas, I. Ara, 2019, BMC Geriatrics.

Role of objectively measured sedentary behaviour in physical performance, frailty and mortality among older adults: A short systematic review

I. Ara, F. Garcia-Garcia, B. del Pozo-Cruz, 2017, European journal of sport science.

Involvement of plasma miRNAs, muscle miRNAs and mitochondrial miRNAs in the pathophysiology of frailty

F. Garcia-Garcia, D. Acuña-Castroviejo, I. Rusanova, 2019, Experimental Gerontology.

Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans

F. Garcia-Garcia, Ana Guerra-Librero, D. Acuña-Castroviejo, 2018, Oxidative medicine and cellular longevity.

Association between telomere length, frailty and death in older adults

L. Rodríguez-Mañas, F. Garcia-Garcia, F. Rodríguez‐Artalejo, 2020, GeroScience.

Prospective Changes in the Distribution of Movement Behaviors Are Associated With Bone Health in the Elderly According to Variations in their Frailty Levels

S. Chastin, J. Losa-Reyna, L. Rodríguez-Mañas, 2020, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Impact of nutritional status according to GLIM criteria on the risk of incident frailty and mortality in community-dwelling older adults.

L. Rodríguez-Mañas, F. Garcia-Garcia, R. Rueda, 2020, Clinical nutrition.

Better Nutritional Status Is Positively Associated with mRNA Expression of SIRT1 in Community-Dwelling Older Adults in the Toledo Study for Healthy Aging.

L. Rodríguez-Mañas, F. Garcia-Garcia, S. Walter, 2018, The Journal of nutrition.

A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts

S. Bandinelli, A. Sinclair, J. Tegnér, 2021, GeroScience.

Patterns of circulating fat-soluble vitamins and carotenoids and risk of frailty in four European cohorts of older adults

S. Bandinelli, L. Ferrucci, F. Garcia-Garcia, 2019, European Journal of Nutrition.

The prevalence of frailty syndrome in an older population from Spain. The Toledo study for healthy aging

L. Rodriguez-Manas, A. Alfaro-Acha, L. Rodríguez-Mañas, 2011, The journal of nutrition, health & aging.

Homocysteine and C-reactive protein levels are associated with frailty in older Spaniards: The Toledo Study for Healthy Aging.

L. Rodríguez-Mañas, F. Garcia-Garcia, A. Carrillo-Vico, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

Sex Differences in the Association between Serum Levels of Testosterone and Frailty in an Elderly Population: The Toledo Study for Healthy Aging

A. Alfaro-Acha, L. Rodríguez-Mañas, F. Garcia-Garcia, 2012, PloS one.

The Standardization of Frailty Phenotype Criteria Improves Its Predictive Ability: The Toledo Study for Healthy Aging.

L. Rodríguez-Mañas, F. Garcia-Garcia, A. Esteban, 2017, Journal of the American Medical Directors Association.

Homocysteine levels are associated with bone resorption in pre-frail and frail Spanish women: The Toledo Study for Healthy Aging

L. Rodríguez-Mañas, A. Carrillo-Vico, J. Guerrero, 2018, Experimental Gerontology.

Frailty is associated with objectively assessed sedentary behaviour patterns in older adults: Evidence from the Toledo Study for Healthy Aging (TSHA)

Ignacio Ara, Jorge Marín-Puyalto, Asier Mañas, 2017, PloS one.

Cognitive Performance across 3 Frailty Phenotypes: Toledo Study for Healthy Aging.

J. Losa-Reyna, A. Alfaro-Acha, L. Rodríguez-Mañas, 2017, Journal of the American Medical Directors Association.

Brain-Derived Neurotrophic Factor as a Marker of Cognitive Frailty.

F. Garcia-Garcia, M. Inglés, C. Mas-Bargues, 2016, The journals of gerontology. Series A, Biological sciences and medical sciences.

Higher sRAGE Levels Predict Mortality in Frail Older Adults with Cardiovascular Disease

S. Bandinelli, L. Rodríguez-Mañas, F. Garcia-Garcia, 2021, Gerontology.

Differential Association of Frailty and Sarcopenia With Mortality and Disability: Insight Supporting Clinical Subtypes of Frailty.

L. Rodríguez-Mañas, F. Garcia-Garcia, B. Davies., 2022, Journal of the American Medical Directors Association.

Life-long spontaneous exercise does not prolong lifespan but improves health span in mice

Jose Viña, L. Rodríguez-Mañas, F. Garcia-Garcia, 2013, Longevity & healthspan.

A protective personal factor against disability and dependence in the elderly: an ordinal regression analysis with nine geographically-defined samples from Spain

J. Benito-León, P. Martínez-Martín, J. Virués-Ortega, 2017, BMC Geriatrics.

Endocrinology of Aging From a Muscle Function Point of View: Results From the Toledo Study for Healthy Aging.

J. Losa-Reyna, A. Alfaro-Acha, L. Rodríguez-Mañas, 2017, Journal of the American Medical Directors Association.

The sit-to-stand muscle power test: An easy, inexpensive and portable procedure to assess muscle power in older people

J. Alcazar, J. Losa-Reyna, C. Rodriguez-Lopez, 2018, Experimental Gerontology.

Effects of concurrent exercise training on muscle dysfunction and systemic oxidative stress in older people with COPD

J. Alcazar, J. Losa-Reyna, C. Rodriguez-Lopez, 2019, Scandinavian journal of medicine & science in sports.

A New Frailty Score for Experimental Animals Based on the Clinical Phenotype: Inactivity as a Model of Frailty

L. Rodríguez-Mañas, F. Garcia-Garcia, J. Viña, 2017, The journals of gerontology. Series A, Biological sciences and medical sciences.

Association between endothelial dysfunction and frailty: the Toledo Study for Healthy Aging

L. Rodríguez-Mañas, F. Garcia-Garcia, L. Carcaillon, 2014, AGE.

Which one came first: movement behavior or frailty? A cross‐lagged panel model in the Toledo Study for Healthy Aging

J. Losa-Reyna, L. Rodríguez-Mañas, I. Ara, 2020, Journal of cachexia, sarcopenia and muscle.

Role of oestrogens on oxidative stress and inflammation in ageing

L. Rodríguez-Mañas, F. Garcia-Garcia, J. Gambini, 2013, Hormone molecular biology and clinical investigation.

Frailty Is Associated With Lower Expression of Genes Involved in Cellular Response to Stress: Results From the Toledo Study for Healthy Aging.

L. Rodríguez-Mañas, F. Garcia-Garcia, S. Walter, 2017, Journal of the American Medical Directors Association.

Reallocating Accelerometer-Assessed Sedentary Time to Light or Moderate- to Vigorous-Intensity Physical Activity Reduces Frailty Levels in Older Adults: An Isotemporal Substitution Approach in the TSHA Study.

A. Alfaro-Acha, L. Rodríguez-Mañas, I. Ara, 2017, Journal of the American Medical Directors Association.

Oxidative Stress Is Related to Frailty, Not to Age or Sex, in a Geriatric Population: Lipid and Protein Oxidation as Biomarkers of Frailty

L. Rodríguez-Mañas, F. Garcia-Garcia, M. Inglés, 2014, Journal of the American Geriatrics Society.

Dual effects of insulin resistance on mortality and function in non-diabetic older adults: findings from the Toledo Study of Healthy Aging

A. Sinclair, L. Rodríguez-Mañas, F. Garcia-Garcia, 2021, GeroScience.

Relation Between Genetic Factors and Frailty in Older Adults.

L. Rodríguez-Mañas, F. Garcia-Garcia, M. Inglés, 2019, Journal of the American Medical Directors Association.

Identificación de polimorfismos de un solo nucleótido relacionados con la fragilidad

L. Rodríguez-Mañas, F. Garcia-Garcia, M. Inglés, 2018, Revista Española de Geriatría y Gerontología.

Serum uric acid concentrations and risk of frailty in older adults

L. Rodríguez-Mañas, F. Garcia-Garcia, F. Rodríguez‐Artalejo, 2016, Experimental Gerontology.

Can Physical Activity Offset the Detrimental Consequences of Sedentary Time on Frailty? A Moderation Analysis in 749 Older Adults Measured With Accelerometers.

J. Losa-Reyna, L. Rodríguez-Mañas, I. Ara, 2019, Journal of the American Medical Directors Association.

The medium-term consequences of a COVID-19 lockdown on lifestyle among Spanish older people with hypertension, pulmonary disease, cardiovascular disease, musculoskeletal disease, depression, and cancer

J. Ayuso-Mateos, L. Rodríguez-Mañas, I. Ara, 2022, Epidemiology and health.

Changes in Health Behaviors, Mental and Physical Health among Older Adults under Severe Lockdown Restrictions during the COVID-19 Pandemic in Spain

J. Ayuso-Mateos, L. Rodríguez-Mañas, I. Ara, 2021, medRxiv.

Compositional Influence of Movement Behaviours on Bone Health during Ageing.

S. Chastin, J. Losa-Reyna, L. Rodríguez-Mañas, 2019, Medicine and science in sports and exercise.

The Impact of Movement Behaviors on Bone Health in Elderly with Adequate Nutritional Status: Compositional Data Analysis Depending on the Frailty Status

S. Chastin, J. Losa-Reyna, L. Rodríguez-Mañas, 2019, Nutrients.

Physical performance measures in frailty screening: diagnostic and prognostic accuracy in the Toledo Study of Healthy Ageing.

L. Rodríguez-Mañas, F. Garcia-Garcia, B. Rodríguez-Sánchez, 2022, Maturitas.

Importance of medical data preprocessing in predictive modeling and risk factor discovery for the frailty syndrome

Andreas Holzinger, Ernestina Menasalvas, Leocadio Rodríguez-Mañas, 2019, BMC Medical Informatics and Decision Making.

Sedentary behaviour, physical activity, and sarcopenia among older adults in the TSHA: isotemporal substitution model

L. Rodríguez-Mañas, I. Ara, F. Garcia-Garcia, 2019, Journal of cachexia, sarcopenia and muscle.

Residual effects of 12 weeks of power‐oriented resistance training plus high‐intensity interval training on muscle dysfunction, systemic oxidative damage, and antioxidant capacity after 10 months of training cessation in older people with COPD

J. Alcazar, J. Losa-Reyna, C. Rodriguez-Lopez, 2023, Scandinavian journal of medicine & science in sports.

A new operational definition of frailty: the Frailty Trait Scale.

L. Rodríguez-Mañas, F. Garcia-Garcia, J. L. Larrión, 2014, Journal of the American Medical Directors Association.

Relative sit-to-stand power cut-off points and their association with negatives outcomes in older adults

J. Alcazar, J. Losa-Reyna, A. Alfaro-Acha, 2020, Scientific Reports.

The Effect of the Stretch-Shortening Cycle in the Force–Velocity Relationship and Its Association With Physical Function in Older Adults With COPD

J. Alcazar, J. Losa-Reyna, C. Rodriguez-Lopez, 2019, Front. Physiol..

Short- and Long-Term Effects of Concurrent Strength and HIIT Training in Octogenarians with COPD.

J. Alcazar, I. Ara, F. Garcia-Garcia, 2017, Journal of aging and physical activity.

Frailty as a Major Factor in the Increased Risk of Death and Disability in Older People With Diabetes.

A. Sinclair, L. Rodríguez-Mañas, F. Garcia-Garcia, 2016, Journal of the American Medical Directors Association.

Associations between sedentary time, physical activity and bone health among older people using compositional data analysis

S. Chastin, J. Losa-Reyna, L. Rodríguez-Mañas, 2018, PloS one.

Association of regional muscle strength with mortality and hospitalisation in older people.

L. Rodríguez-Mañas, F. Garcia-Garcia, L. Alegre, 2015, Age and ageing.

The Force-Velocity Relationship in Older People: Reliability and Validity of a Systematic Procedure

J. Alcazar, C. Rodriguez-Lopez, A. Alfaro-Acha, 2017, International Journal of Sports Medicine.

Age and gender, two key factors in the associations between physical activity and strength during the ageing process.

A. Alfaro-Acha, L. Rodríguez-Mañas, I. Ara, 2014, Maturitas.

Frailty Trait Scale-Short Form: A Frailty Instrument for Clinical Practice.

J. Losa-Reyna, A. Alfaro-Acha, L. Rodríguez-Mañas, 2020, Journal of the American Medical Directors Association.

Higher levels of endogenous estradiol are associated with frailty in postmenopausal women from the toledo study for healthy aging.

L. Rodríguez-Mañas, F. Garcia-Garcia, J. Tresguerres, 2012, The Journal of clinical endocrinology and metabolism.

Breaking sedentary time predicts future frailty in inactive older adults: A cross-lagged panel model.

J. Losa-Reyna, L. Rodríguez-Mañas, I. Ara, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

A Short Communication on the Need for Interdisciplinary Action with Families with Deaf Children Who Use Bilateral Cochlear Implants

Manuel López-Torrijo, F. García-García, 2016 .

Force-velocity profiling in older adults: An adequate tool for the management of functional trajectories with aging

J. Alcazar, J. Losa-Reyna, C. Rodriguez-Lopez, 2018, Experimental Gerontology.

Low relative mechanical power in older adults: An operational definition and algorithm for its application in the clinical setting

J. Alcazar, J. Losa-Reyna, A. Alfaro-Acha, 2020, Experimental Gerontology.

Relationship between self-reported visual impairment and worsening frailty transition states in older people: a longitudinal study

L. Rodríguez-Mañas, F. Garcia-Garcia, J. Carnicero, 2021, Aging Clinical and Experimental Research.

[Frailty: a phenotype under review].

L. Rodríguez Mañas, J. L. Larrión Zugasti, F. García-García, 2011, Gaceta sanitaria.

Associations between frailty and serum N-terminal propeptide of type I procollagen and 25-hydroxyvitamin D in older Spanish women: The Toledo Study for Healthy Aging

L. Rodríguez-Mañas, F. Garcia-Garcia, A. Carrillo-Vico, 2015, Experimental Gerontology.

Increased levels of soluble Receptor for Advanced Glycation End-products (RAGE) are associated with a higher risk of mortality in frail older adults.

L. Rodríguez-Mañas, F. Garcia-Garcia, J. Dartigues, 2019, Age and ageing.

Gait Velocity and Chair Sit-Stand-Sit Performance Improves Current Frailty-Status Identification

Nora Millor, Marisol Gómez, Pablo Lecumberri, 2017, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

Automatic Evaluation of the 30-s Chair Stand Test Using Inertial/Magnetic-Based Technology in an Older Prefrail Population

Mikel Izquierdo, Leocadio Rodríguez-Mañas, Nora Millor, 2013, IEEE Journal of Biomedical and Health Informatics.

Effect of a short multicomponent exercise intervention focused on muscle power in frail and pre frail elderly: A pilot trial

J. Alcazar, J. Losa-Reyna, A. Alfaro-Acha, 2019, Experimental Gerontology.

AUTOMATIC EVALUATION OF THE 30S CHAIR STAND TEST USING INERTIAL / MAGNETIC BASED TECHNOLOGY IN AN OLDER PRE-FRAIL POPULATION

Leocadio Rodríguez-Mañas, Nora Millor, Marisol Gómez, 2022 .

Performance of the European Working Group on Sarcopenia in Older People algorithm in screening older adults for muscle mass assessment.

F. Garcia-Garcia, L. Rodríguez Mañas, L. Gutiérrez-Robledo, 2015, Age and ageing.

Comparison of available equations to estimate sit-to-stand muscle power and their association with gait speed and frailty in older people: Practical applications for the 5-rep sit-to-stand test

J. Alcazar, J. Losa-Reyna, L. Rodríguez-Mañas, 2021, Experimental Gerontology.

Nonlinear relationship between waist to hip ratio, weight and strength in elders: is gender the key?

L. Rodríguez-Mañas, M. A. de la Torre, J. Carnicero, 2015, Biogerontology.

Global performance of executive function is predictor of risk of frailty and disability in older adults

J. Losa-Reyna, A. Alfaro-Acha, L. Rodríguez-Mañas, 2017, The journal of nutrition, health & aging.

Running title: Obesity and frailty in two population-based cohorts

L. Rodríguez-Mañas, F. Rodríguez‐Artalejo, P. Guallar-Castillón, 2016 .

Frailty Is Associated With Lower Expression of Genes Involved in Cellular Response to Stress: Results From the Toledo Study for Healthy Aging.

L. Rodríguez-Mañas, S. Walter, E. López-Hernández, 2017, Journal of the American Medical Directors Association.

Fat Mass Accounts for Insulin Resistance Impact on Functional Decline and Mortality in Nondiabetic Older Adults.

L. Mañas, J. Carnicero, M. El Assar, 2023, Journal of the American Medical Directors Association.

Role of objectively measured sedentary behaviour in physical performance, frailty and mortality among older adults: A short systematic review

I. Ara, B. del Pozo-Cruz, A. Mañas, 2017, European journal of sport science.

Relationship of endogenous plasma concentrations of β-hydroxy β-methyl butyrate (HMB) with frailty in community dwelling older adults with type-2 diabetes mellitus.

J. López-Pedrosa, J. Carnicero, A. Álvarez-Bustos, 2024, The journal of nutrition, health & aging.

Associations between frailty and serum N-terminal propeptide of type I procollagen and 25-hydroxyvitamin D in older Spanish women: The Toledo Study for Healthy Aging

L. Rodríguez-Mañas, A. Carrillo-Vico, J. Guerrero, 2015, Experimental Gerontology.

Better nutritional status is positively associated with mRNA expression of SIRT1 in community-dwelling older adults in the Toledo Study for Healthy Aging

L. Rodríguez-Mañas, F. Garcia-Garcia, S. Walter, 2018 .

Association between endogenous plasma beta‐hydroxy‐beta‐methylbutyrate levels and frailty in community‐dwelling older people

L. Rodríguez-Mañas, J. Carnicero, F. García-García, 2023, Journal of cachexia, sarcopenia and muscle.

The Medium-Term Changes in Health-Related Behaviours among Spanish Older People Lifestyles during Covid-19 Lockdown

J. Ayuso-Mateos, L. Rodríguez-Mañas, F. Garcia-Garcia, 2022, The journal of nutrition, health & aging.

[Identification of single nucleotide polymorphisms related to frailty].

L. Rodríguez-Mañas, M. Inglés, M. Dromant, 2018, Revista espanola de geriatria y gerontologia.