Shunichi Takeda

发表

Shunichi Takeda, Junko Murai, 2014 .

Effects of double-strand break repair proteins on vertebrate telomere structure

Chao Wei, Shunichi Takeda, Rose Skopp, 2002, Nucleic Acids Res..

Applicability Domain of Active Learning in Chemical Probe Identification: Convergence in Learning from Non-Specific Compounds and Decision Rule Clarification

J B Brown, Ahsan Habib Polash, Shunichi Takeda, 2019, Molecules.

Active learning efficiently converges on rational limits of toxicity prediction and identifies patterns for molecule design

Christin Rakers, Ahsan Habib Polash, Shunichi Takeda, 2020 .

Active learning effectively identifies a minimal set of maximally informative and asymptotically performant cytotoxic structure-activity patterns in NCI-60 cell lines.

Shunichi Takeda, Takumi Nakano, J. B. Brown, 2020, RSC medicinal chemistry.

Chemogenomic Active Learning's Domain of Applicability on Small, Sparse qHTS Matrices: A Study Using Cytochrome P450 and Nuclear Hormone Receptor Families

Christin Rakers, J B Brown, Rifat Ara Najnin, 2018, ChemMedChem.

Chemical-Space-Based de Novo Design Method To Generate Drug-Like Molecules

Hiromasa Kaneko, Kimito Funatsu, Shunichi Takeda, 2016, J. Chem. Inf. Model..

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells

Shunichi Takeda, Shinya Matsuura, Hiroshi Tauchi, 2002, Nature.

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination.

Xin Wang, Shunichi Takeda, Yasuhiro Murakawa, 2007, Molecular cell.

A Novel Approach Using DNA-Repair–Deficient Chicken DT40 Cell Lines for Screening and Characterizing the Genotoxicity of Environmental Contaminants

Kyungho Choi, Xin Wang, Kyunghee Ji, 2009, Environmental health perspectives.

Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination.

Shunichi Takeda, Y. Taniguchi, T. Paull, 2007, Molecular cell.

Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform.

Ruili Huang, Raymond R Tice, Menghang Xia, 2015, Mutagenesis.

Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition

James H. Doroshow, Yves Pommier, Shunichi Takeda, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

Shunichi Takeda, Kum Kum Khanna, Malcolm F. White, 2008, Nature.

Differential usage of non-homologous end-joining and homologous recombination in double strand break repair.

Shunichi Takeda, Y. Taniguchi, S. Takeda, 2006, DNA repair.

Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group

George Iliakis, Shunichi Takeda, Minoru Takata, 2001, Oncogene.

Increased ratio of targeted to random integration after transfection of chicken B cell lines

Jean-Marie Buerstedde, Shunichi Takeda, J. Buerstedde, 1991, Cell.

Homologous Recombination, but Not DNA Repair, Is Reduced in Vertebrate Cells Deficient in RAD52

Akira Shinohara, Yuko Yamaguchi-Iwai, Jean-Marie Buerstedde, 1998, Molecular and Cellular Biology.

Reduced X-Ray Resistance and Homologous Recombination Frequencies in a RAD54−/− Mutant of the Chicken DT40 Cell Line

Yuko Yamaguchi-Iwai, Jean-Marie Buerstedde, Shunichi Takeda, 1997, Cell.

Differential and Common DNA Repair Pathways for Topoisomerase I- and II-Targeted Drugs in a Genetic DT40 Repair Cell Screen Panel

Yves Pommier, Shunichi Takeda, Junko Murai, 2013, Molecular Cancer Therapeutics.

Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM

Hiroshi Arakawa, Shunichi Takeda, Minoru Takata, 2005, The EMBO journal.

Sister Chromatid Exchanges Are Mediated by Homologous Recombination in Vertebrate Cells

Yuko Yamaguchi-Iwai, Shunichi Takeda, Minoru Takata, 1999, Molecular and Cellular Biology.

Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair‐deficient chicken DT40 cell lines

Ruili Huang, Menghang Xia, Srilatha Sakamuru, 2011, Environmental and molecular mutagenesis.

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

Shunichi Takeda, Tim Hunt, T. Hunt, 2008, Nature Reviews Molecular Cell Biology.

Rad51‐deficient vertebrate cells accumulate chromosomal breaks prior to cell death

Akira Shinohara, Shunichi Takeda, Minoru Takata, 1998, The EMBO journal.

Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity.

Yves Pommier, Yoshiyuki Shibata, Shunichi Takeda, 2015, Cell reports.

Homologous-pairing activity of the human DNA-repair proteins Xrcc3⋅Rad51C

Shigeyuki Yokoyama, Shunichi Takeda, Minoru Takata, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms

Kyungho Choi, Tetsushi Sakuma, Jun Nakamura, 2018, Environmental and molecular mutagenesis.