J. Hill

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Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Nguyen H. Tran, Vidyashankara G. Iyer, Andreas C. Themistocleous, 2021, The Lancet.

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

P. Klenerman, T. Wrin, C. Petropoulos, 2021, Nature Communications.

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial.

Nguyen H. Tran, Andreas C. Themistocleous, David J. Smith, 2020, Lancet.

T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial

Nguyen H. Tran, Andreas C. Themistocleous, P. Klenerman, 2020, Nature Medicine.

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

Nguyen H. Tran, Kathryn Jones, Tao Dong, 2020, The Lancet.

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Nguyen H. Tran, Vidyashankara G. Iyer, Andreas C. Themistocleous, 2020, Lancet.

Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison

G. Rodger, C. Groves, D. Stuart, 2020, The Lancet Infectious Diseases.

Efficacy of Typhoid Conjugate Vaccine in Nepal: An Interim Analysis of a Participant-and Observer-Blinded Randomized Phase III Trial

S. Baker, K. Neuzil, A. Pollard, 2019, The New England Journal of Medicine.

Efficacy and immunogenicity of a Vi-tetanus toxoid conjugate vaccine in the prevention of typhoid fever using a controlled human infection model of Salmonella Typhi: a randomised controlled, phase 2b trial

Ly-Mee Yu, A. Pollard, B. Angus, 2017, The Lancet.

SIMON: Open-Source Knowledge Discovery Platform

Mark M. Davis, Rachel L. Spreng, Lindsay C. Dahora, 2020, bioRxiv.

Epigenetics in Sepsis: Understanding Its Role in Endothelial Dysfunction, Immunosuppression, and Potential Therapeutics

A. Pollard, R. Drury, Jennifer Hill, 2019, Front. Immunol..

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Nguyen H. Tran, Andreas C. Themistocleous, P. Klenerman, 2020, Nature Medicine.

Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern

P. Klenerman, J. Knight, P. Phalora, 2021, Nature Communications.

Homologous and heterologous re-challenge with Salmonella Typhi and Salmonella Paratyphi A in a randomised controlled human infection model

A. Simmons, A. Pollard, B. Angus, 2020, PLoS neglected tropical diseases.

Transcriptomics in Human Challenge Models

A. Pollard, Jennifer Hill, C. Blohmke, 2017, Front. Immunol..

Induction of Cell Cycle and NK Cell Responses by Live-Attenuated Oral Vaccines against Typhoid Fever

G. Dougan, H. Nakaya, A. Pollard, 2017, Front. Immunol..

Interferon-driven alterations of the host’s amino acid metabolism in the pathogenesis of typhoid fever

James C. Wright, O. Ramilo, A. Mejias, 2016, The Journal of experimental medicine.

Host restriction, pathogenesis and chronic carriage of typhoidal Salmonella

Jennifer Hill, Amber J. Barton, Christoph J. Blohmke, 2021, FEMS microbiology reviews.

Enhanced Susceptibility to Citrobacter rodentium Infection in MicroRNA-155-Deficient Mice

A. Enright, C. Abreu-Goodger, E. Vigorito, 2012, Infection and Immunity.

MicroRNA-155-Deficient Mice rodentium Infection in Enhanced Susceptibility to Citrobacter

A. Enright, C. Abreu-Goodger, E. Vigorito, 2014 .

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Calliope A. Dendrou, I. Pavord, J. Todd, 2021, Cell.

Efficacy of typhoid conjugate vaccine in Nepal: final results of a phase 3, randomised, controlled trial

K. Neuzil, A. Pollard, M. Voysey, 2021, The Lancet. Global health.

Efficacy of Typhoid Conjugate Vaccine in Nepal: An Interim Analysis of a Participant-and Observer-Blinded Randomized Phase III Trial

S. Baker, K. Neuzil, A. Pollard, 2019, The New England journal of medicine.

Investigation of the role of typhoid toxin in acute typhoid fever in a human challenge model

G. Dougan, G. Obermoser, A. Pollard, 2019, Nature Medicine.

Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

S. Clare, G. Dougan, J. Parkhill, 2015, PLoS neglected tropical diseases.

Genetic Susceptibility to Enteric Fever in Experimentally Challenged Human Volunteers

A. Pollard, Liye Chen, E. Jones, 2021, bioRxiv.

Association of Antibody-Dependent Neutrophil Phagocytosis With Distinct Antibody Glycosylation Profiles Following Typhoid Vaccination

A. Pollard, M. Voysey, J. Nouta, 2021, Frontiers in Tropical Diseases.

Vi-Vaccinations Induce Heterogeneous Plasma Cell Responses That Associate With Protection From Typhoid Fever

G. Obermoser, H. Maecker, A. Pollard, 2020, Frontiers in Immunology.

Vi-specific serological correlates of protection for typhoid fever

Rachel L. Spreng, Lindsay C. Dahora, B. Gunn, 2020, The Journal of experimental medicine.

IgA and IgG1 Specific to Vi Polysaccharide of Salmonella Typhi Correlate With Protection Status in a Typhoid Fever Controlled Human Infection Model

Rachel L. Spreng, Lindsay C. Dahora, S. Alam, 2019, Front. Immunol..

Salmonella Typhi Vi capsule prime-boost vaccination induces convergent and functional antibody responses

Lindsay C. Dahora, G. Cavet, S. Alam, 2021, Science Immunology.

Obesity Differs from Diabetes Mellitus in Antibody and T Cell Responses Post COVID-19 Recovery

P. Klenerman, F. H. Mollah, P. Abraham, 2023, medRxiv.

Correction: Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

S. Clare, G. Dougan, J. Parkhill, 2015, PLoS neglected tropical diseases.

Molecular correlates of vaccine-induced protection against typhoid fever

D. Kelly, J. Trück, A. Pollard, 2023, The Journal of clinical investigation.

A tool for evaluating heterogeneity in avidity of polyclonal antibodies

Rachel L. Spreng, Lindsay C. Dahora, E. Jongert, 2023, Frontiers in Immunology.

A Salmonella Typhi Controlled Human Infection Study for Assessing Correlation between Bactericidal Antibodies and Protection against Infection Induced by Typhoid Vaccination

A. Pollard, C. Dold, Jennifer Hill, 2021, Microorganisms.

Persistence of Antibody After a Vi-Tetanus Toxoid Conjugate Vaccine and Effect of Boosting With a Plain Polysaccharide Vaccine on Vi Antibody and Antigen-Specific B Cells

A. Pollard, Jennifer Hill, M. Moore, 2021, Frontiers in Tropical Diseases.

Edinburgh Research Explorer Signatures of adaptation in human invasive Salmonella Typhimurium ST313 populations from sub-Saharan Africa

S. Clare, G. Dougan, J. Parkhill, 2018 .

Author Correction: Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Nguyen H. Tran, Andreas C. Themistocleous, M. Wand, 2021, Nature Medicine.

Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19

Calliope A. Dendrou, I. Pavord, G. Rodger, 2022, The Lancet Digital Health.

Early transcriptional responses to human enteric fever challenge

A. Pollard, H. Dobinson, T. Darton, 2023, Infection and immunity.

A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus

T. Wangrangsimakul, B. Kronsteiner, D. Paris, 2022, bioRxiv.

Early transcriptional responses to human enteric fever challenge

A. Pollard, H. Dobinson, T. Darton, 2023, Infection and immunity.