J. B. Locke

发表

Genetic Environment and Stability of cfr in Methicillin-Resistant Staphylococcus aureus CM05

A. Mankin, Jeffrey B Locke, K. Shaw, 2011, Antimicrobial Agents and Chemotherapy.

Novel Ribosomal Mutations in Staphylococcus aureus Strains Identified through Selection with the Oxazolidinones Linezolid and Torezolid (TR-700)

M. Hilgers, Jeffrey B Locke, K. Shaw, 2009, Antimicrobial Agents and Chemotherapy.

Anthracimycin, a potent anthrax antibiotic from a marine-derived actinomycete.

S. Nam, W. Fenical, Jeffrey B Locke, 2013, Angewandte Chemie.

Results of the surveillance of Tedizolid activity and resistance program: in vitro susceptibility of gram-positive pathogens collected in 2011 and 2012 from the United States and Europe.

J. Deane, D. Sahm, Jeffrey B Locke, 2015, Diagnostic microbiology and infectious disease.

Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio).

Tristan M. Carland, V. Nizet, L. Gerwick, 2012, Developmental and comparative immunology.

Differential expression and intrachromosomal evolution of the sghC 1 q genes in zebrafish ( Danio rerio )

Tristan M. Carland, V. Nizet, L. Gerwick, 2011 .

Characterization of In Vitro Resistance Development to the Novel Echinocandin CD101 in Candida Species

Jeffrey B Locke, K. Bartizal, D. Zuill, 2016, Antimicrobial Agents and Chemotherapy.

Comparison of In Vitro Killing Activity of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in RPMI-1640 in the Absence and Presence of Human Serum

A. Borman, G. Kardos, Jeffrey B Locke, 2021, Microorganisms.

The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing.

V. Nizet, J. Buchanan, E. Hanski, 2008, Cell host & microbe.

Mutations in Ribosomal Protein L3 Are Associated with Oxazolidinone Resistance in Staphylococci of Clinical Origin

M. Hilgers, Jeffrey B Locke, K. Shaw, 2009, Antimicrobial Agents and Chemotherapy.

Linezolid-Resistant Staphylococcus aureus Strain 1128105, the First Known Clinical Isolate Possessing the cfr Multidrug Resistance Gene

R. Goering, J. Deane, D. Sahm, 2014, Antimicrobial Agents and Chemotherapy.

Structure-Activity Relationships of Diverse Oxazolidinones for Linezolid-Resistant Staphylococcus aureus Strains Possessing the cfr Methyltransferase Gene or Ribosomal Mutations

J. Stein, M. Hilgers, Gracia Morales, 2010, Antimicrobial Agents and Chemotherapy.

Tedizolid for the management of human infections: in vitro characteristics.

Jeffrey B Locke, K. Shaw, K. Bartizal, 2014, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Rezafungin (CD101) demonstrates potent in vitro activity against Aspergillus, including azole-resistant Aspergillus fumigatus isolates and cryptic species

Jeffrey B Locke, K. Bartizal, N. Wiederhold, 2018, The Journal of antimicrobial chemotherapy.

CD101 Prophylactic Dose Rationale for Prevention of Aspergillus, Candida, and Pneumocystis Infections

S. Flanagan, K. Bartizal, T. Sandison, 2018 .

Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion.

V. Nizet, J. Buchanan, V. Ostland, 2010, Diseases of aquatic organisms.

CD101: a novel long‐acting echinocandin

D. Perlin, Jeffrey B Locke, Grayson W. Hough, 2016, Cellular microbiology.

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against Candida Species

A. Borman, G. Kardos, L. Majoros, 2020, Journal of fungi.

Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate

S. Flanagan, Jeffrey B Locke, K. Bartizal, 2014, Drug Metabolism and Disposition.

Absorption , Distribution , Metabolism , and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate s

S. Flanagan, Jeffrey B Locke, K. Bartizal, 2014 .

DMD056697 1275..1284

S. Flanagan, Jeffrey B Locke, K. Bartizal, 2014 .

Tricyclic GyrB/ParE (TriBE) Inhibitors: A New Class of Broad-Spectrum Dual-Targeting Antibacterial Agents

Felice C. Lightstone, Toan B. Nguyen, Sergio E. Wong, 2013, PloS one.

In vitro activity of rezafungin against common and rare Candida species and Saccharomyces cerevisiae

A. Borman, G. Kardos, Jeffrey B Locke, 2019, The Journal of antimicrobial chemotherapy.

Evaluation of the Post‐Antifungal Effect of Rezafungin and Micafungin against Candida albicans, Candida parapsilosis and Candida glabrata

M. Castanheira, P. Rhomberg, M. Pfaller, 2022, Mycoses.

Streptococcus iniae Capsule Impairs Phagocytic Clearance and Contributes to Virulence in Fish

V. Nizet, M. Neely, J. Buchanan, 2006, Journal of bacteriology.

The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae.

V. Nizet, J. Buchanan, R. Aziz, 2010, Microbiology.

Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection.

V. Nizet, J. Buchanan, Jeffrey B Locke, 2007, Diseases of aquatic organisms.

Low Fitness Cost of the Multidrug Resistance Gene cfr

A. Mankin, Jeffrey B Locke, K. Shaw, 2011, Antimicrobial Agents and Chemotherapy.

Streptococcus iniae M-Like Protein Contributes to Virulence in Fish and Is a Target for Live Attenuated Vaccine Development

V. Nizet, J. Buchanan, R. Aziz, 2008, PloS one.

Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.

M. Hilgers, M. Teng, M. Cunningham, 2013, Journal of medicinal chemistry.

In vitro activity of the novel echinocandin CD101 at pH 7 and 4 against Candida spp. isolates from patients with vulvovaginal candidiasis

J. Sobel, Jeffrey B Locke, K. Bartizal, 2017, The Journal of antimicrobial chemotherapy.

Elevated Linezolid Resistance in Clinical cfr-Positive Staphylococcus aureus Isolates Is Associated with Co-Occurring Mutations in Ribosomal Protein L3

J. Stein, M. Hilgers, Gracia Morales, 2010, Antimicrobial Agents and Chemotherapy.