A. D'Ippolito

发表

Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers

Christopher M. Vockley, Timothy E. Reddy, G. Crawford, 2015, Nature Biotechnology.

Phosphatidylinositol 3-Kinase (PI3K) Signaling via Glycogen Synthase Kinase-3 (Gsk-3) Regulates DNA Methylation of Imprinted Loci*

B. Doble, B. Aronow, K. Mclaughlin, 2010, The Journal of Biological Chemistry.

Highly Specific Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements

Timothy E. Reddy, G. Crawford, Lingyun Song, 2015, Nature Methods.

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

Ian C. McDowell, William H. Majoros, Christopher M. Vockley, 2016, Cell.

Genomic signatures of high-altitude adaptation and chromosomal polymorphism in geladas

Christina M. Bergey, Andrew S. Burrell, J. Wall, 2022, Nature Ecology & Evolution.

Genomic signatures of high-altitude adaptation and chromosomal polymorphism in geladas

Christina M. Bergey, Andrew S. Burrell, J. Wall, 2022, Nature ecology & evolution.

High-altitude adaptation and incipient speciation in geladas

Christina M. Bergey, Andrew S. Burrell, J. Wall, 2021 .

Perspectives on ENCODE

Xintao Wei, Christopher B. Burge, Jason Liu, 2020, Nature.

Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding

Ian C. McDowell, William H. Majoros, Christopher M. Vockley, 2018, Genome research.

Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells.

Charles A. Gersbach, Timothy E. Reddy, Anthony M. D’Ippolito, 2016, Cell stem cell.

Erythroid lineage chromatin accessibility maps facilitate identification and validation of NFIX as a fetal hemoglobin repressor

J. Carulli, J. Shearstone, Mudit Chaand, 2023, Communications biology.

Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells

Gavin D. Meredith, B. Doble, Yulei N. Wang, 2015, Molecular biology of the cell.

Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids.

Ian C. McDowell, William H. Majoros, Charles A. Gersbach, 2018, Cell systems.

Abstract C091: Preclinical evaluation of PK, PD, and antitumor activity of the oral, non-covalent, potent and highly selective CDK7 inhibitor, SY-5609, provides rationale for clinical development in multiple solid tumor indications

J. Marineau, N. Rajagopal, W. Zamboni, 2019 .

From Prescription to Transcription: Genome Sequence as Drug Target

Timothy E. Reddy, Cong Guo, A. D'Ippolito, 2015, Cell.

518MO Tolerability and preliminary clinical activity of SY-5609, a highly potent and selective oral CDK7 inhibitor, in patients with advanced solid tumors

G. Shapiro, D. Juric, G. Hodgson, 2021, Annals of Oncology.

Activity of SY-5609, an oral, noncovalent, potent, and selective CDK7 inhibitor, in preclinical models of colorectal cancer.

M. Eaton, N. Rajagopal, G. Hodgson, 2020 .

Human genome-wide measurement of drug-responsive regulatory activity

Ian C. McDowell, William H. Majoros, Christopher M. Vockley, 2018, Nature Communications.

Gene Expression Profiling in Mouse Embryonic Stem Cells Reveals Glycogen Synthase Kinase-3-Dependent Targets of Phosphatidylinositol 3-Kinase and Wnt/β-Catenin Signaling Pathways

B. Doble, C. M. Bartman, Jennifer N Egelston, 2014, Front. Endocrinol..