S. Fletcher

发表

Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates

S. P. Fletcher, Mireia Sidera, Philipp Schäfer, 2017, Nature Communications.

Highly enantioselective rhodium-catalyzed cross-coupling of boronic acids and racemic allyl halides

S. P. Fletcher, F. W. Goetzke, Jesús González, 2019, Nature Protocols.

Asymmetric cross-coupling of alkyl, alkenyl and (hetero)aryl nucleophiles with racemic allyl halides.

S. P. Fletcher, Mireia Sidera, Philipp Schäfer, 2017, Chemical communications.

A Reversible, Unidirectional Molecular Rotary Motor Driven by Chemical Energy

Michael M. Pollard, Frédéric Dumur, Ben L Feringa, 2005, Science.

Living and immortal polymerization of seven and six membered lactones to high molecular weights with aluminum salen and salan catalysts

S. P. Fletcher, J. P. Macdonald, Mireia Sidera, 2016 .

Transmission of chirality through space and across length scales.

S. P. Fletcher, Sarah M. Morrow, Andrew J. Bissette, 2017, Nature nanotechnology.

Conformational Effects on Physical-Organic Descriptors: The Case of Sterimol Steric Parameters

R. Paton, S. P. Fletcher, Alexandre V. Brethomé, 2018, ACS Catalysis.

Synthesis of enantiomerically enriched (R)-13C-labelled 2-aminoisobutyric acid (Aib) by conformational memory in the alkylation of a derivative of L-alanine

S. P. Fletcher, Jordi Solà, J. Clayden, 2011, Beilstein journal of organic chemistry.

High‐Power Actuation from Molecular Photoswitches in Enantiomerically Paired Soft Springs

Benjamin Matt, Nathalie Katsonis, Tibor Kudernac, 2017, Angewandte Chemie.

Fluorinated Azobenzenes for Shape-Persistent Liquid Crystal Polymer Networks.

N. Katsonis, Supitchaya Iamsaard, S. Aßhoff, 2016, Angewandte Chemie.

Conversion of light into macroscopic helical motion.

J. Cornelissen, N. Katsonis, Supitchaya Iamsaard, 2014, Nature chemistry.

Coupled Metabolic Cycles Allow Out‐of‐Equilibrium Autopoietic Vesicle Replication

P. Kukura, S. P. Fletcher, M. Lebedeva, 2020, Angewandte Chemie.

Physical autocatalysis driven by a bond-forming thiol–ene reaction

S. P. Fletcher, B. Odell, Andrew J. Bissette, 2014, Nature Communications.

Synthesis of the bicyclic dienone core of the antitumor agent ottelione B.

S. P. Fletcher, D. Clive, S. Fletcher, 2002, Chemical communications.

An autonomously oscillating supramolecular self-replicator

S. P. Fletcher, A. Engwerda, R. Scanes, 2022, Nature Chemistry.

A chemically fuelled self-replicator

Ignacio Colomer, S. P. Fletcher, S. Morrow, 2019, Nature Communications.

A transient self-assembling self-replicator

Ignacio Colomer, S. P. Fletcher, S. Morrow, 2018, Nature Communications.

Retooling Asymmetric Conjugate Additions for Sterically Demanding Substrates with an Iterative Data-Driven Approach

R. Paton, S. P. Fletcher, Alexandre V. Brethomé, 2019, ACS catalysis.

An astrophysically-relevant mechanism for amino acid enantiomer enrichment.

B. Feringa, S. P. Fletcher, R. Jagt, 2007, Chemical communications.

Ligand Design for Asymmetric Catalysis: Combining Mechanistic and Chemoinformatics Approaches

Robert S. Paton, Ruchuta Ardkhean, Stephen P. Fletcher, 2020 .

Acceleration of lipid reproduction by emergence of microscopic motion

N. Katsonis, T. Kudernac, S. P. Fletcher, 2020, Nature Communications.

Current methods for asymmetric halogenation of olefins.

S. P. Fletcher, Alejandro Castellanos, S. Fletcher, 2011, Chemistry.

Formation of quaternary centers by copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents.

S. P. Fletcher, P. Roth, Mireia Sidera, 2013, Angewandte Chemie.

Enantio‐ and Diastereoselective Suzuki–Miyaura Coupling with Racemic Bicycles

M. Mortimore, F. W. Goetzke, S. Fletcher, 2019, Angewandte Chemie.

Scale-Up of a Rh-Catalyzed Asymmetric sp3–sp2 Suzuki–Miyaura-Type Reaction

Mireia Sidera Portela, S. P. Fletcher, Laura Cunningham, 2022, Organic process research & development.

Selection from a pool of self-assembling lipid replicators

Ignacio Colomer, A. Borissov, S. Fletcher, 2020, Nature Communications.

Synthetic control of retinal photochemistry and photophysics in solution.

P. Kukura, T. Claridge, S. P. Fletcher, 2014, Journal of the American Chemical Society.

Molecular machines for catalysis

Stephen P. Fletcher, Lucy van Dijk, Michael J. Tilby, 2018 .

Enantioselective Conjugate Addition Catalyzed by a Copper Phosphoramidite Complex: Computational and Experimental Exploration of Asymmetric Induction

Q. Peng, R. Paton, S. P. Fletcher, 2017 .

Mechanisms of autocatalysis.

S. P. Fletcher, Andrew J Bissette, Stephen P Fletcher, 2013, Angewandte Chemie.

Building blocks of life: Growing the seeds of homochirality.

S. P. Fletcher, S. Fletcher, 2009, Nature chemistry.

Mechanismen der Autokatalyse

Andrew J. Bissette, S. Fletcher, 2013 .

Dissipative self-assembly, competition and inhibition in a self-reproducing protocell model

S. P. Fletcher, Elias A J Post, S. Fletcher, 2020, Chemical science.

Catalytic asymmetric synthesis of carbocyclic C-nucleosides

S. P. Fletcher, Sourabh Mishra, F. Modicom, 2022, Communications Chemistry.

Copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents to cyclic enones to form quaternary centers

S. P. Fletcher, P. Roth, Mireia Sidera, 2013, Nature Protocols.

Catalytic Enantioselective Synthesis of 3-Piperidines from Arylboronic Acids and Pyridine

Sourabh Mishra, Sedef Karabiyikoglu, S. Fletcher, 2023, Journal of the American Chemical Society.

Asymmetric Synthesis of Nortropanes via Rh-Catalyzed Allylic Arylation

Kirsten E. Christensen, Yan Zhang, F. W. Goetzke, 2022, ACS catalysis.

Additions to Racemates: A Strategy for Developing Asymmetric Cross-Coupling Reactions

F. W. Goetzke, S. Fletcher, 2021, Synlett.

Catalytic Asymmetric S uzuki– M iyaura Couplings

S. P. Fletcher, F. W. Goetzke, L. V. Dijk, 2019 .

Synthesis of the Taxol Core via Catalytic Asymmetric 1,4-Addition of an Alkylzirconium Nucleophile.

S. P. Fletcher, J. Wang, S. Fletcher, 2020, Organic letters.

A molecular assembler that produces polymers

S. P. Fletcher, A. Engwerda, S. Fletcher, 2020, Nature Communications.

Barrierless Photoisomerization of 11-cis Retinal Protonated Schiff Base in Solution.

Jong Min Lim, P. Kukura, T. Claridge, 2015, Journal of the American Chemical Society.

Backbone modification of retinal induces protein-like excited state dynamics in solution.

P. Kukura, S. P. Fletcher, M. Liebel, 2012, Journal of the American Chemical Society.

Asymmetric conjugate additions and allylic alkylations using nucleophiles generated by hydro- or carbometallation.

S. P. Fletcher, Rebecca M. Maksymowicz, Andrew J. Bissette, 2015, Chemistry.

An alternative synthesis of the breast cancer drug fulvestrant (Faslodex®): catalyst control over C-C bond formation.

S. P. Fletcher, Diego Caprioglio, S. Fletcher, 2015, Chemical communications.

Emergence and Rearrangement of Dynamic Supramolecular Aggregates Visualized by Interferometric Scattering Microscopy

P. Kukura, S. P. Fletcher, M. Lebedeva, 2020, ACS nano.

A catalytic asymmetric cross-coupling approach to the synthesis of cyclobutanes

S. P. Fletcher, F. W. Goetzke, Lucy van Dijk, 2021, Nature Chemistry.

Formation of quaternary centres by copper catalysed asymmetric conjugate addition to β-substituted cyclopentenones with the aid of a quantitative structure–selectivity relationship† †Electronic supplementary information (ESI) available. CCDC 1811310–1811312, 1818574 and 1818575. For ESI and crystall

R. Paton, S. P. Fletcher, R. Ardkhean, 2018, Chemical science.

Catalytic asymmetric synthesis of geminal-dicarboxylates† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01786g

S. P. Fletcher, N. Mistry, S. Fletcher, 2018, Chemical science.

Controlling the Kinetics of Self-Reproducing Micelles by Catalyst Compartmentalization in a Biphasic System

Elias A J Post, S. Fletcher, 2019, The Journal of organic chemistry.

Potential for minimal self-replicating systems in a dynamic combinatorial library of equilibrating imines

S. P. Fletcher, S. Morrow, Andrew J. Bissette, 2017 .

Controlling axial conformation in 2-arylpyridines and 1-arylisoquinolines: application to the asymmetric synthesis of QUINAP by dynamic thermodynamic resolution.

S. P. Fletcher, J. Clayden, J. McDouall, 2009, Journal of the American Chemical Society.

Rhodium-catalysed asymmetric allylic arylation of racemic halides with arylboronic acids

S. P. Fletcher, Mireia Sidera, S. Fletcher, 2015, Nature Chemistry.

Mechanistic Studies on a Cu-Catalyzed Asymmetric Allylic Alkylation with Cyclic Racemic Starting Materials.

E. Rideau, T. Claridge, S. P. Fletcher, 2017, Journal of the American Chemical Society.

Novel Disulfides with Antitumour Efficacy and Specificity

L. Penn, Rebecca Griffiths, W. Wong, 2005 .

Visualization of the spontaneous emergence of a complex, dynamic, and autocatalytic system

J. Ortega-Arroyo, P. Kukura, S. P. Fletcher, 2016, Proceedings of the National Academy of Sciences.

Structure‐function studies for in vitro chemical inhibition of Fcγ receptor–mediated phagocytosis

R. Langler, S. P. Fletcher, D. Branch, 2007, Transfusion.

The S2 Oxygen Atoms Are Essential for the Pronounced Fungitoxicity of the Sulfur-Rich Natural Product, Dysoxysulfone

E. O'brien, S. Bewick, R. Langler, 2005 .

Mechanism of Autocatalysis

S. P. Fletcher, Andrew J. Bissette, S. Fletcher, 2014 .

Selection between Competing Self-Reproducing Lipids: Succession and Dynamic Activation

S. P. Fletcher, R. Scanes, Michael G. Howlett, 2021, JACS Au.

An Asymmetric Suzuki-Miyaura Approach to Prostaglandins: Synthesis of Tafluprost.

S. P. Fletcher, F. W. Goetzke, Roman Kučera, 2020, Organic letters.

A chemically fuelled self-replicator

Ignacio Colomer, S. Morrow, Sarah M. Morrow, 2019, Nature Communications.

8.32 Hydrogenolysis of Allyl and Benzyl Halides and Related Compounds

S. P. Fletcher, Andrew J. Bissette, S. Fletcher, 2014 .

Mechanistic investigation of Rh(I)-catalyzed asymmetric Suzuki-Miyaura coupling with racemic allyl halides

R. Paton, T. Claridge, S. P. Fletcher, 2019 .

Asymmetric Suzuki-Miyaura coupling of heterocycles via Rhodium-catalysed allylic arylation of racemates

Mireia Sidera, Philipp Schäfer, Thomas Palacin, 2017, Nature Communications.

Cu-catalyzed asymmetric addition of sp²-hybridized zirconium nucleophiles to racemic allyl bromides.

S. P. Fletcher, Mireia Sidera, S. Fletcher, 2015, Chemical communications.

Non-stabilized nucleophiles in Cu-catalysed dynamic kinetic asymmetric allylic alkylation

E. Rideau, S. P. Fletcher, Hengzhi You, 2015, Nature.

Catalytic asymmetric carbon–carbon bond formation using alkenes as alkylmetal equivalents

S. P. Fletcher, P. Roth, Rebecca M. Maksymowicz, 2012, Nature Chemistry.

Hydrometallation-asymmetric conjugate addition: application to complex molecule synthesis.

S. P. Fletcher, P. Roth, Rebecca M. Maksymowicz, 2013, Chemical communications.

From autocatalysis to survival of the fittest in self-reproducing lipid systems

Michael G. Howlett, S. Fletcher, 2023, Nature Reviews Chemistry.

Novel applications of physical autocatalysis

Andrew J. Bissette, S. Fletcher, 2015, Origins of Life and Evolution of Biospheres.

A Reversible, Unidirectional Molecular Rotary Motor Driven by Chemical Energy

Michael M. Pollard, B. Feringa, F. Dumur, 2005, Science.

Nanometer-range communication of stereochemical information by reversible switching of molecular helicity.

S. P. Fletcher, Jordi Solà, J. Clayden, 2010, Angewandte Chemie.

Formal radical cyclization onto benzene rings: a general method and its use in the synthesis of ent-nocardione A.

S. P. Fletcher, D. Clive, Dazhan Liu, 2004, The Journal of organic chemistry.

Mechanistic investigation of Rh(i)-catalysed asymmetric Suzuki–Miyaura coupling with racemic allyl halides

T. Claridge, G. Lloyd‐Jones, R. Ardkhean, 2021, Nature Catalysis.

Chelation enables selectivity control in enantioconvergent Suzuki–Miyaura cross-couplings on acyclic allylic systems

Stephen J. Webster, Violeta Stojalnikova, S. Fletcher, 2024, Nature chemistry.

Enantiomerically enriched tetrahydropyridine allyl chlorides

R. Paton, S. P. Fletcher, Alexandre V. Brethomé, 2019, Chemical Science.

Acyclic quaternary centers from asymmetric conjugate addition of alkylzirconium reagents to linear trisubstituted enones† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc02811j Click here for additional data file.

Zhenbo Gao, S. Fletcher, 2016, Chemical science.

Desymmetrization of meso-bisphosphates via rhodium catalyzed asymmetric allylic arylation

S. P. Fletcher, Reece Jacques, Robert D. C. Pullin, 2019, Tetrahedron.

Desymmetrization of meso-bisphosphates using copper catalysis and alkylzirconocene nucleophiles

S. P. Fletcher, Reece Jacques, Robert D. C. Pullin, 2019, Nature Communications.

Diverse Cyclopentenes via Enantioselective Cu-Catalyzed Desymmetrization

S. P. Fletcher, Reece Jacques, Robert D. C. Pullin, 2018 .

Catalytic enantioselective synthesis of naturally occurring butenolides via hetero-allylic alkylation and ring closing metathesis.

B. Feringa, A. Minnaard, S. P. Fletcher, 2011, Organic letters.

Copper catalyzed asymmetric synthesis of chiral allylic esters.

B. Feringa, S. P. Fletcher, Koen Geurts, 2006, Journal of the American Chemical Society.

Rhodium‐Catalyzed Asymmetric Arylation of Cyclobutenone Ketals

F. W. Goetzke, S. Fletcher, David Egea-Arrebola, 2023, Angewandte Chemie.

Formal radical cyclization onto benzene rings--a general method proceeding via cross-conjugated dienones.

Mingzhao Zhu, S. P. Fletcher, D. Clive, 2003, Chemical communications.

Oligomerization Driven by Phase Separation

Ignacio Colomer, S. P. Fletcher, I. Myrgorodska, 2020, ChemSystemsChem.

Hindered diarylether and diarylsulfone bisphosphine ligands: Atropisomerism and palladium complexes

S. P. Fletcher, J. Clayden, J. Senior, 2010 .