N. Cantone

发表

Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymp

Jon R. Wilson, A. Good, P. Trojer, 2016, Journal of medicinal chemistry.

A Twenty-year Experience With Endoscopic Therapy for Symptomatic Primary Sclerosing Cholangitis

R. Kozarek, D. Patterson, Michael Gluck, 2008, Journal of clinical gastroenterology.

EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.

P. Trojer, Shilpi Arora, R. Cummings, 2014, Chemistry & biology.

Risk stratification for colon neoplasia: screening strategies using colonoscopy and computerized tomographic colonography.

R. Kozarek, J. Dominitz, D. Schembre, 2006, Gastroenterology.

Treatment of Barrett's esophagus with early neoplasia: a comparison of endoscopic therapy and esophagectomy.

D. Low, D. Schembre, O. Lin, 2008, Gastrointestinal endoscopy.

Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials.

P. Sandy, Y. Leblanc, H. Jayaram, 2016, Journal of medicinal chemistry.

Patient satisfaction scores for endoscopic procedures: impact of a survey-collection method.

R. Kozarek, D. Patterson, Nico Cantone, 2007, Gastrointestinal endoscopy.

GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.

A. Good, P. Sandy, Y. Leblanc, 2022, Journal of medicinal chemistry.

Identification and characterization of second-generation EZH2 inhibitors with extended residence times and improved biological activity

P. Trojer, R. Sims, Shilpi Arora, 2021, The Journal of biological chemistry.

S-adenosyl methionine is necessary for inhibition of the methyltransferase G9a by the lysine 9 to methionine mutation on histone H3

R. Cummings, C. Allis, H. Jayaram, 2016, Proceedings of the National Academy of Sciences.

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637).

Y. Leblanc, H. Jayaram, R. Sims, 2016, ACS medicinal chemistry letters.

Design, Synthesis, and Pharmacological Evaluation of Second Generation EZH2 Inhibitors with Long Residence Time.

P. Trojer, R. Sims, Shilpi Arora, 2020, ACS medicinal chemistry letters.

Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor.

R. Sims, R. Cummings, F. Poy, 2020, ACS medicinal chemistry letters.

Early Drug‐Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors

R. Cummings, R. Sims, J. Audia, 2020, ChemMedChem.

Treatment of Barrett's esophagus with early neoplasia: a comparison of endoscopic therapy and esophagectomy.

D. Low, D. Schembre, O. Lin, 2008, Gastrointestinal endoscopy.