Dan M Roden

发表

Evaluating electronic health record data sources and algorithmic approaches to identify hypertensive individuals

Joshua C Denny, Pedro L Teixeira, Wei-Qi Wei, 2017, J. Am. Medical Informatics Assoc..

Improving the phenotype risk score as a scalable approach to identifying patients with Mendelian disease

Lisa Bastarache, Joshua C Denny, Dan M Roden, 2019, J. Am. Medical Informatics Assoc..

Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.

Lisa Bastarache, Joshua C Denny, Dan M Roden, 2017, Assay and drug development technologies.

Development of a System for Postmarketing Population Pharmacokinetic and Pharmacodynamic Studies Using Real‐World Data From Electronic Health Records

Hannah L Weeks, Cole Beck, Elizabeth McNeer, 2020, Clinical pharmacology and therapeutics.

DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions

Joshua C Denny, Wei-Qi Wei, Dan M Roden, 2021, J. Am. Medical Informatics Assoc..

Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation.

Thomas Meitinger, Dan M Roden, Josée Dupuis, 2008, European heart journal.

Identifying genetically driven clinical phenotypes using linear mixed models

Lisa Bastarache, Joshua C Denny, Dan M Roden, 2016, Nature Communications.

Modeling drug exposure data in electronic medical records: an application to warfarin.

Joshua C Denny, Dan M Roden, Hua Xu, 2011, AMIA ... Annual Symposium proceedings. AMIA Symposium.

Modulators of normal electrocardiographic intervals identified in a large electronic medical record.

Joshua C Denny, Dan M Roden, Melissa A. Basford, 2011, Heart rhythm.

Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies.

Peter Kraft, Joshua C Denny, Uwe Völker, 2016, Gastroenterology.

Genetic variation in the rhythmonome: ethnic variation and haplotype structure in candidate genes for arrhythmias.

Dan M Roden, Dana C Crawford, William S Bush, 2009, Pharmacogenomics.

Nature Genetics Advance Online Publication Genetic Association Study of Qt Interval Highlights Role for Calcium Signaling Pathways in Myocardial Repolarization

Michael J Ackerman, Christian Gieger, Thomas Meitinger, 2022 .

A prognostic model based on readily available clinical data enriched a pre-emptive pharmacogenetic testing program.

Joshua C Denny, Dan M Roden, Melissa A. Basford, 2016, Journal of clinical epidemiology.

Defining the Cellular Phenotype of “Ankyrin-B Syndrome” Variants: Human ANK2 Variants Associated With Clinical Phenotypes Display a Spectrum of Activities in Cardiomyocytes

Dan M Roden, Antoine Leenhardt, Denis Escande, 2007, Circulation.

Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records

Joshua C Denny, Dan M Roden, Dana C Crawford, 2010, Genetics in Medicine.

Genetic determinants of response to warfarin during initial anticoagulation.

Dan M Roden, Marylyn D Ritchie, Scott M Dudek, 2008, The New England journal of medicine.

Genetic and Clinical Risk Prediction Model for Postoperative Atrial Fibrillation

Dan M Roden, William S Bush, Dawood Darbar, 2015, Circulation. Arrhythmia and electrophysiology.

Drug-Induced Long QT Syndrome

Dan M Roden, Dawood Darbar, D. Roden, 2010, Pharmacological Reviews.

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Yusuke Nakamura, Dan M Roden, Matthew Oetjens, 2013, The Lancet.

Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome.

Yan Guo, Yu Shyr, Dan M Roden, 2014, Journal of the American College of Cardiology.

Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants

Lisa Bastarache, Joshua C Denny, Dan M Roden, 2017, Science Translational Medicine.

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

Hynek Pikhart, Fernando Pires Hartwig, Joshua C Denny, 2017, The lancet. Diabetes & endocrinology.

[Guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Executive summary].

Dan M Roden, Silvia G Priori, Martin Borggrefe, 2006, Revista espanola de cardiologia.

Probing the mechanisms underlying modulation of quinidine sensitivity to cardiac IKs block by protein kinase A‐mediated IKs phosphorylation

Dan M Roden, Tao Yang, Wei Zhang, 2009, British journal of pharmacology.

Drug-induced long QT and torsade de pointes: recent advances

Dan M Roden, D. Roden, P. Kannankeril, 2007, Current opinion in cardiology.

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

Dan M Roden, Beverley Balkau, Pierre Lindenbaum, 2013, Nature Genetics.

Whole Exome Sequencing Identifies a Causal RBM20 Mutation in a Large Pedigree With Familial Dilated Cardiomyopathy

Dan M Roden, Quinn S Wells, Charles C Hong, 2013, Circulation. Cardiovascular genetics.

A clinical prediction model to estimate risk for 30-day adverse events in emergency department patients with symptomatic atrial fibrillation.

Dan M Roden, Cathy A Jenkins, Frank E Harrell, 2009, Annals of emergency medicine.

Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial

Dan M Roden, Silvia G Priori, E. Kaufman, 2017, JAMA cardiology.

Calmodulin Kinase II and Arrhythmias in a Mouse Model of Cardiac Hypertrophy

Dan M Roden, Wei Zhang, Robert Passier, 2002, Circulation.

A polymorphism in HLA-G modifies statin benefit in asthma

Dan M Roden, Hua Xu, Joshua Denny, 2014, The Pharmacogenomics Journal.

Using systems approaches to address challenges for clinical implementation of pharmacogenomics

Joshua C Denny, Dan M Roden, Josh F Peterson, 2014, Wiley interdisciplinary reviews. Systems biology and medicine.

Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation.

Michael J Ackerman, Dan M Roden, Wojciech Zareba, 2010, Circulation.

Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation.

Michael J Ackerman, Dan M Roden, Wojciech Zareba, 2010, Journal of the American College of Cardiology.

In vivo identification of genes that modify ether-a-go-go-related gene activity in Caenorhabditis elegans may also affect human cardiac arrhythmia.

Dan M Roden, Ping Yang, Alfred L George, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

Dan M Roden, Kari Stefansson, Gudmar Thorleifsson, 2011, Nature Genetics.

KCNH2-K897T Is a Genetic Modifier of Latent Congenital Long-QT Syndrome

Dan M Roden, Alessandro Vicentini, Lia Crotti, 2005, Circulation.

Factors affecting the degree of QT prolongation with drug challenge in a large cohort of normal volunteers.

Dan M Roden, Shannon Carter, D. Roden, 2011, Heart rhythm.

Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization

Dan M Roden, Aravinda Chakravarti, Stefan Kääb, 2009, Circulation.

SCN5A Variation Is Associated With Electrocardiographic Traits in the Jackson Heart Study

Dan M Roden, Dana C Crawford, Kristin Brown-Gentry, 2011, Circulation. Cardiovascular genetics.

Inactivating mutations in NPC1L1 and protection from coronary heart disease.

John Spertus, Thomas Meitinger, Joshua C Denny, 2014, The New England journal of medicine.

Electrophysiologic Substrate in Congenital Long QT Syndrome: Noninvasive Mapping With Electrocardiographic Imaging (ECGI)

Dan M Roden, Ramya Vijayakumar, Yoram Rudy, 2014, Circulation.

Genome-wide association studies in pharmacogenomics: successes and lessons

Dan M Roden, Alison A Motsinger-Reif, Nancy J Cox, 2013, Pharmacogenetics and genomics.

Data re-identification: societal safeguards.

Dan M Roden, Russ B Altman, Isaac S Kohane, 2013, Science.

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records.

Michael J Ackerman, Joshua C Denny, Dan M Roden, 2016, JAMA.

Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia.

Dan M Roden, Harold Snieder, Vanessa Marshall, 2012, Journal of the American College of Cardiology.

Cardiac potassium channel dysfunction in sudden infant death syndrome.

Dan M Roden, Carlos G Vanoye, Lia Crotti, 2007, Journal of molecular and cellular cardiology.

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Gonçalo Abecasis, Dan M Roden, Christopher M Haggerty, 2018, JAMA.