W. E. A. Witte

Mechanistic incorporation of FcRn binding in plasma and endosomes in a whole body PBPK model for large molecules

Anna Park, Brian C Mackness, M. Sargentini‐Maier, 2023, Journal of Pharmacokinetics and Pharmacodynamics.

Target and Tissue Selectivity Prediction by Integrated Mechanistic Pharmacokinetic-Target Binding and Quantitative Structure Activity Modeling

M. Danhof, G. V. Westen, A. Vlot, 2017, The AAPS Journal.

Modelling the delay between PK and EEG effects of morphine in rats ; binding kinetic versus effect compartment models

Peletier, M. Danhof, V. Rottschäfer, 2018 .

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

Leigh A. Stoddart, R. Wade, R. Leurs, 2017, Drug discovery today.

Utilising computational power to improve drug safety: predicting and understanding tissue selectivity

G. V. Westen, W. E. A. Witte, 2016 .

Target and Tissue Selectivity Prediction by Integrated Mechanistic Pharmacokinetic-Target Binding and Quantitative Structure Activity Modeling

Gerard J. P. van Westen, Piet H. van der Graaf, Meindert Danhof, 2017, The AAPS Journal.

The implications of target saturation for the use of drug–target residence time

Piet H. van der Graaf, Meindert Danhof, M. Danhof, 2018, Nature Reviews Drug Discovery.

Assessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans

M. Danhof, S. Visser, O. Della Pasqua, 2015, Pharmaceutical Research.