Palak Gosalia

发表

Table 3, Probe and Analog Submissions to MLSMR (Evotec) for P. falciparum G-6PDH antagonists

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure A6E, LCMS purity data at 214 nm for ML291 2nd batch –submitted to the MLSMR (SID 134228465, CID 52940465); LCMS retention time: 3.125 min; purity at 214 nm = 97.5%

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Table 1, Listing of all Assays and AIDs for this project

Susanne Heynen-Genel, Shenghua Shi, Thomas D.Y. Chung, 2010 .

Table 5, Probe and Analog Submissions to the MLMR (BioFocus DPI)

Susanne Heynen-Genel, Thomas D.Y. Chung, Palak Gosalia, 2010 .

Figure A6F, HRMS data for ML291 2nd batch –submitted to the MLSMR (SID 134228465, CID 52940465); HRMS m/z calculated for C16H17ClN3O6S [M + H+]: 414.0521, found 414.0522

Stefan Vasile, Eigo Suyama, Anthony B. Pinkerton, 2013 .

[Figure], Critical Path Flowchart for KOR Antagonist Project

Susanne Heynen-Genel, Thomas D.Y. Chung, Palak Gosalia, 2010 .

Scheme 1, Synthesis of ML304

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

[Table], EXPERIMENTAL RESULTS FOR SID 123083137 ON OTHER TARGETS

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Table 8, Comparison of prior art and current probe

Susanne Heynen-Genel, Thomas D.Y. Chung, Palak Gosalia, 2010 .

Figure 1, Summary of the hit structures for the KOP antagonist project

Susanne Heynen-Genel, Thomas D.Y. Chung, Palak Gosalia, 2010 .

Table 9, Comparative summary of two current probes CID5236771 & CID44601470 to literature examples

Susanne Heynen-Genel, Thomas D.Y. Chung, Palak Gosalia, 2010 .

Table 3, Probe and Analog Submissions to MLSMR (BioFocus DPI) for APJ Antagonists

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Scheme 1, Synthesis of ML276

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure A6C, LCMS purity data at 214 nm for ML291 1st batch (SID 123083137, CID 52940465); LCMS retention time: 3.074 min; purity at 214 nm = 95.4%

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure 3, Flowchart Summary of Screening Results

Stefan Vasile, Eigo Suyama, Ying Su, 2011 .

Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2012, Journal of medicinal chemistry.