Eliot Sugarman

发表

Table 3, Probe and Analog Submissions to MLSMR (Evotec) for P. falciparum G-6PDH antagonists

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure A6E, LCMS purity data at 214 nm for ML291 2nd batch –submitted to the MLSMR (SID 134228465, CID 52940465); LCMS retention time: 3.125 min; purity at 214 nm = 97.5%

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure A6F, HRMS data for ML291 2nd batch –submitted to the MLSMR (SID 134228465, CID 52940465); HRMS m/z calculated for C16H17ClN3O6S [M + H+]: 414.0521, found 414.0522

Stefan Vasile, Eigo Suyama, Anthony B. Pinkerton, 2013 .

Scheme 1, Synthesis of ML377

Susanne Heynen-Genel, Stefan Vasile, Eigo Suyama, 2015 .

Scheme 1, Synthesis of ML304

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

[Table], EXPERIMENTAL RESULTS FOR SID 123083137 ON OTHER TARGETS

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Table 3, Probe and Analog Submissions to MLSMR (BioFocus DPI) for APJ Antagonists

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Scheme 1, Synthesis of ML276

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure A6C, LCMS purity data at 214 nm for ML291 1st batch (SID 123083137, CID 52940465); LCMS retention time: 3.074 min; purity at 214 nm = 95.4%

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2013 .

Figure 3, Flowchart Summary of Screening Results

Stefan Vasile, Eigo Suyama, Ying Su, 2011 .

Table 3, Probe and Analog Submissions to MLSMR (Evotec) for TAG inhibitors

Susanne Heynen-Genel, Eigo Suyama, Layton H. Smith, 2015 .

Maximizing lipophilic efficiency: the use of Free-Wilson analysis in the design of inhibitors of acetyl-CoA carboxylase.

Eliot Sugarman, Zhengrong Zhao, Wei Song, 2012, Journal of medicinal chemistry.

Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro.

Stefan Vasile, Eigo Suyama, Michael Vicchiarelli, 2012, Journal of medicinal chemistry.

Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1.

Eliot Sugarman, Angel Guzman-Perez, G. S. Walker, 2011, ACS medicinal chemistry letters.