Fengzhi Chen

Living cell mTORC1 inhibition reporter mTIR reveals nutrient-sensing targets of histone deacetylase inhibitor

Lin Feng, Shuiming Li, Xiaoduo Xie, 2023, bioRxiv.

Nitidine chloride inhibits mTORC1 signaling through ATF4-mediated Sestrin2 induction and targets IGF2R for lysosomal degradation.

Canrong Li, Fengzhi Chen, Shujun Peng, 2024, Life sciences.

TORSEL, a 4EBP1-based mTORC1 live-cell sensor, reveals nutrient-sensing targeting by histone deacetylase inhibitors

Canrong Li, Xiao Yan, Chuxin Lu, 2024, Cell & bioscience.