M. C. Wehr

发表

Multiparametric Assays for Accelerating Early Drug Discovery.

Philipp E. Geyer, M. Rossner, M. Wehr, 2020, Trends in pharmacological sciences.

Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling.

N. Tapon, M. Gstaiger, O. Rinner, 2010, Molecular cell.

Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning.

Mathias V. Schmidt, V. Stein, J. Deussing, 2022, Cell reports.

Split-Cre Complementation Indicates Coincident Activity of Different Genes In Vivo

R. Sprengel, F. Kirchhoff, A. Reichenbach, 2009, PloS one.

High cholesterol level is essential for myelin membrane growth

Klaus-Armin Nave, Wiebke Möbius, K. Nave, 2005, Nature Neuroscience.

Improved Split TEV GPCR β-arrestin-2 Recruitment Assays via Systematic Analysis of Signal Peptide and β-arrestin Binding Motif Variants

M. Rossner, M. Wehr, Michael C. Wehr, 2022, Biosensors.

Spironolactone is an antagonist of NRG1‐ERBB4 signaling and schizophrenia‐relevant endophenotypes in mice

P. Falkai, K. Nave, Weiqi Zhang, 2017, EMBO molecular medicine.

Kibra Is a Regulator of the Salvador/Warts/Hippo Signaling Network

B. Thompson, N. Tapon, R. Brain, 2010, Developmental cell.

Evolutionary and molecular facts link the WWC protein family to Hippo signaling.

H. Pavenstädt, B. Skryabin, V. Gerke, 2014, Molecular biology and evolution.

Characterizing Dynamic Protein-Protein Interactions Using the Genetically Encoded Split Biosensor Assay Technique Split TEV.

M. Rossner, M. Wehr, Michael C. Wehr, 2017, Methods in molecular biology.

Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila

Rebecca E. Saunders, Rachael Instrell, Ming Jiang, 2012, Nature Cell Biology.

Disturbed Clockwork Resetting in Sharp-1 and Sharp-2 Single and Double Mutant Mice

G. Eichele, K. Nave, M. Rossner, 2008, PloS one.

Mice Lacking the Circadian Modulators SHARP1 and SHARP2 Display Altered Sleep and Mixed State Endophenotypes of Psychiatric Disorders

M. Rossner, R. Taneja, H. Oster, 2014, PloS one.

Cholesterol Regulates the Endoplasmic Reticulum Exit of the Major Membrane Protein P0 Required for Peripheral Myelin Compaction

K. Nave, Eva-Maria Krämer-Albers, W. Möbius, 2009, The Journal of Neuroscience.

Split protein biosensor assays in molecular pharmacological studies.

M. Rossner, M. Wehr, Moritz J Rossner, 2016, Drug discovery today.

Monitoring activities of receptor tyrosine kinases using a universal adapter in genetically encoded split TEV assays

M. Rossner, M. Wehr, Sven P. Wichert, 2019, Cellular and Molecular Life Sciences.

Monitoring regulated protein-protein interactions using split TEV

Tobias M. Fischer, K. Nave, M. Rossner, 2006, Nature Methods.

Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

S. Papiol, M. Rossner, M. Wehr, 2018, Scientific Reports.

Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts

M. Rossner, Sabrina Galinski, Sven P. Wichert, 2018, Scientific Reports.

Dissecting intercellular and intracellular signaling networks with barcoded genetic tools.

M. Rossner, M. Wehr, Michael C. Wehr, 2021, Current opinion in chemical biology.

Add-on spironolactone as antagonist of the NRG1-ERBB4 signaling pathway for the treatment of schizophrenia: Study design and methodology of a multicenter randomized, placebo-controlled trial

T. Schneider-Axmann, P. Falkai, S. Leucht, 2020, Contemporary clinical trials communications.

Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation

P. Falkai, M. Rossner, A. Schmitt, 2022, Cells.

Comprehensive split TEV based protein-protein interaction screening reveals TAOK2 as a key modulator of Hippo signalling to limit growth.

N. Kannaiyan, Jan P. Wintgens, Vivek K. Sahoo, 2023, Cellular signalling.

Rescue of Comorbid Behavioral and Metabolic Phenotypes of Arrhythmic Mice by Restoring Circadian Cry1/2 Expression in the Suprachiasmatic Nucleus

M. Rossner, D. Landgraf, M. C. Wehr, 2023, Biological psychiatry global open science.

Split protein biosensor assays in molecular pharmacological studies.

M. Rossner, M. C. Wehr, 2016, Drug discovery today.

Monitoring G protein-coupled receptor activation using the protein fragment complementation technique split TEV.

M. Rossner, Sabrina Galinski, Michael C. Wehr, 2015, Methods in molecular biology.

Analysis of transient phosphorylation-dependent protein-protein interactions in living mammalian cells using split-TEV

M. Rossner, M. Wehr, Lisa Reinecke, 2008, BMC biotechnology.

Profiling of ERBB receptors and downstream pathways reveals selectivity and hidden properties of ERBB4 antagonists

Sven P. Wichert, Jan P. Wintgens, L. Popović, 2024, iScience.

Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice

J. Deussing, C. Wotjak, S. Wiechmann, 2024, Science Signaling.

Exploiting Cell-Based Assays to Accelerate Drug Development for G Protein-Coupled Receptors

N. Jensen, M. C. Wehr, Yuxin Wu, 2024, International journal of molecular sciences.