Waylan Bessler

发表

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.

J. Travers, J. Chernoff, A. McDaniel, 2009, Blood.

Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial

Steven P. Angus, B. Korf, G. Cutter, 2021, Nature Medicine.

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells.

J. Chernoff, A. McDaniel, D. Ingram, 2008, Blood.

K-ras Is Critical for Modulating Multiple c-kit-Mediated Cellular Functions in Wild-Type and Nf1+/− Mast Cells1

D. Ingram, Feng-Chun Yang, Shi Chen, 2007, The Journal of Immunology.

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1 (cid:1) / (cid:2) mast cells

J. Chernoff, A. McDaniel, D. Ingram, 2008 .

Human CD34+AC133+VEGFR-2+ cells are not endothelial progenitor cells but distinct, primitive hematopoietic progenitors.

M. Yoder, D. Ingram, M. Saadatzadeh, 2007, Experimental hematology.

PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).

J. Chernoff, M. Radu, J. Gehlhausen, 2021, Human molecular genetics.

Nf1+/- monocytes/macrophages induce neointima formation via CCR2 activation.

R. Mali, R. Kapur, D. Ingram, 2016, Human molecular genetics.

Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation.

R. Mali, R. Kapur, D. Ingram, 2014, The American journal of pathology.

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation.

G. Sandusky, A. Horvai, Amy E Armstrong, 2019, Human molecular genetics.

Neurofibromin-Deficient Myeloid Cells Are Critical Mediators of Aneurysm Formation In Vivo

S. Conway, D. Ingram, C. Hingtgen, 2014, Circulation.

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans.

M. Dinauer, S. Conway, E. A. Lasater, 2010, The Journal of clinical investigation.

Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway.

S. Conway, R. Mali, R. Kapur, 2013, Human molecular genetics.

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17

G. Sandusky, Chi Zhang, Sujung Park, 2020, The Journal of Biological Chemistry.

Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway.

D. Clapp, S. Conway, E. A. Lasater, 2008, Human molecular genetics.

Ketotifen Modulates Mast Cell Chemotaxis to Kit-Ligand, but Does Not Impact Mast Cell Numbers, Degranulation, or Tumor Behavior in Neurofibromas of Nf1-Deficient Mice

G. Sandusky, J. Blakeley, J. Gehlhausen, 2019, Molecular Cancer Therapeutics.

Neurofibromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans.

D. Fulton, D. Ingram, J. Case, 2016, Free radical biology & medicine.

Neuro ﬁ bromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans Free Radical Biology and Medicine

D. Fulton, D. Ingram, J. Case, 2016 .

Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

Steven P. Angus, David C. Jones, M. Ferrer, 2021, PloS one.

Cabozantinib for neurofibromatosis type 1–related plexiform neurofibromas: a phase 2 trial

Michael Fisher, B. Korf, G. Cutter, 2021, Nature Medicine.

Nf 1 phenotypes in regulates multiple c-Kit mediated Ras-MAPK gain-in-function Pak

J. Chernoff, A. McDaniel, D. Ingram, 2008 .

A proteasome-resistant fragment of NIK mediates oncogenic NF-&kgr;B signaling in schwannomas

Steven P. Angus, A. Stemmer-Rachamimov, G. Sandusky, 2018, Human molecular genetics.

Irradiation of Nf1 mutant mouse models of spinal plexiform neurofibromas drives pathologic progression and decreases survival

J. Nakamura, M. Descovich, A. Horvai, 2021, Neuro-oncology advances.

Endothelial Colony Forming Cells and Mesenchymal Stem Cells are Enriched at Different Gestational Ages in Human Umbilical Cord Blood

M. Yoder, D. Ingram, J. Case, 2008, Pediatric Research.

Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1

J. Blakeley, D. Ingram, Michael J Ferguson, 2020, Pediatric blood & cancer.

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17.

G. Sandusky, Chi Zhang, Sujung Park, 2020, The Journal of biological chemistry.

Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation.

R. Mali, R. Kapur, D. Ingram, 2014, The American journal of pathology.

p21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics.

J. Chernoff, A. McDaniel, Sujung Park, 2009, Blood.

Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway.

S. Conway, R. Mali, R. Kapur, 2013, Human molecular genetics.

Nf1 +/ − monocytes/macrophages induce neointima formation via CCR2 activation

David J. Aldous, R. Mali, R. Kapur, 2016 .