Jason E Gestwicki

发表

The three cornerstones of chemical biology: innovative probes, new discoveries, and enabling tools.

Andrea D Thompson, Leah N Makley, Kathryn McMenimen, 2012, ACS chemical biology.

Predicting protein targets for drug-like compounds using transcriptomics

Yan Xia, Ziv Bar-Joseph, Jeffrey L Brodsky, 2018, bioRxiv.

Deconvolution method for specific and nonspecific binding of ligand to multiprotein complex by native mass spectrometry.

Alma L Burlingame, Jason E Gestwicki, S. Guan, 2015, Analytical chemistry.

Inhibitors of protein-protein interactions (PPIs): an analysis of scaffold choices and buried surface area.

Jason E Gestwicki, J. Gestwicki, Xu Ran, 2018, Current opinion in chemical biology.

Binding of Human Nucleotide Exchange Factors to Heat Shock Protein 70 (Hsp70) Generates Functionally Distinct Complexes in Vitro*

Jason E Gestwicki, J. Gestwicki, Jennifer N Rauch, 2013, The Journal of Biological Chemistry.

Synthetic multivalent ligands as probes of signal transduction.

Jason E Gestwicki, Laura L Kiessling, L. Kiessling, 2006, Angewandte Chemie.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Influencing receptor-ligand binding mechanisms with multivalent ligand architecture.

Jason E Gestwicki, Laura L Kiessling, K. Oetjen, 2002, Journal of the American Chemical Society.

Inhibition of Hsp70 by Methylene Blue Affects Signaling Protein Function and Ubiquitination and Modulates Polyglutamine Protein Degradation*

Jason E Gestwicki, J. Gestwicki, W. Pratt, 2010, The Journal of Biological Chemistry.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

Jason E Gestwicki, John Koren, Laura J Blair, 2010, Molecular Neurodegeneration.

Control of multivalent interactions by binding epitope density.

Jason E Gestwicki, Laura L Kiessling, M. Kanai, 2002, Journal of the American Chemical Society.

Heat shock protein 70 (hsp70) as an emerging drug target.

Lyra Chang, Jason E Gestwicki, Christopher G Evans, 2010, Journal of medicinal chemistry.

Cell aggregation by scaffolded receptor clusters.

Jason E Gestwicki, Laura L Kiessling, L. Kiessling, 2002, Chemistry & biology.

Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo

Jason E Gestwicki, J. Gestwicki, K. Duff, 2012, Autophagy.

Harnessing Chaperones to Generate Small-Molecule Inhibitors of Amyloid ß Aggregation

Jason E Gestwicki, I. Graef, G. Crabtree, 2004, Science.