Stacie S Canan

发表

Collaborative virtual screening to elaborate an imidazo[1,2-a]pyridine hit series for visceral leishmaniasis†

O. Engkvist, G. Pairaudeau, H. Nakai, 2020, RSC medicinal chemistry.

Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial

N. Curtin, D. Newell, Lan Z. Wang, 2007, Molecular Cancer Therapeutics.

Potentiation of rifampin activity in a mouse model of tuberculosis by activation of host transcription factor EB

A. Ballabio, K. Chibale, J. Camardo, 2020, PLoS pathogens.

Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization

A. Hoerauf, J. Siekierka, Alexandra Ehrens, 2022, International journal for parasitology. Drugs and drug resistance.

Discovery of Substituted Di(pyridin-2-yl)-1,2,4-thiadiazol-5-amines as Novel Macrofilaricidal Compounds for the Treatment of Human Filarial Infections

A. Hoerauf, S. Menon, Alexandra Ehrens, 2022, Journal of medicinal chemistry.

Discovery of a Stress-Activated Protein Kinase Inhibitor for Lymphatic Filariasis.

D. Mortensen, J. Siekierka, J. Zeldis, 2018, ACS medicinal chemistry letters.

Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

Discovery of the c-Jun N-Terminal Kinase Inhibitor CC-90001.

Y. Satoh, B. Bennett, D. Mortensen, 2021, Journal of medicinal chemistry.

Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection

O. Engkvist, G. Pairaudeau, David Shum, 2023, Journal of medicinal chemistry.

CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization

P. Worland, Shuichan Xu, D. Mortensen, 2015, Molecular Cancer Therapeutics.

The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen.

L. LeBrun, Dan Zhu, B. Pagarigan, 2017, Journal of medicinal chemistry.

Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

Discovery of mammalian target of rapamycin (mTOR) kinase inhibitor CC-223.

P. Worland, D. Mortensen, B. Cathers, 2015, Journal of medicinal chemistry.

Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase-6

A. Renslo, M. Arkin, S. Wheeler, 2023, Journal of medicinal chemistry.

CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization

P. Worland, Shuichan Xu, D. Mortensen, 2015, Molecular Cancer Therapeutics.