Shashank K. Singh

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Synergistic Combination of Gemcitabine and Dietary Molecule Induces Apoptosis in Pancreatic Cancer Cells and Down Regulates PKM2 Expression

Shashank K Singh, S. Vaishnavi, R. Bamezai, 2014, PloS one.

PLGA nanoparticles augmented the anticancer potential of pentacyclic triterpenediol in vivo in mice

Shashank K Singh, D. Mondhe, Amit Kumar, 2016 .

Development and characterization of hyaluronic acid modified PLGA based nanoparticles for improved efficacy of cisplatin in solid tumor.

P. R. Sharma, Shashank K Singh, D. Mondhe, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Therapeutic Targeting of Cancer Cell Metabolism: Role of Metabolic Enzymes, Oncogenes and Tumor Suppressor Genes

A. Qazi, A. Hussain, Shashank K Singh, 2012 .

Understanding histone deacetylases in the cancer development and treatment: an epigenetic perspective of cancer chemotherapy.

A. Qazi, A. Hussain, A. Saxena, 2012, DNA and cell biology.

Oncogenic BRAF, endoplasmic reticulum stress, and autophagy: Crosstalk and therapeutic targets in cutaneous melanoma.

Shashank K Singh, M. Bhagat, Rafiq A. Rather, 2020, Mutation research.

The Role of Endocannabinoid System in Neuroprotection: Molecular Targets and Therapeutic Opportunities

Sonia Thapa, Shashank K. Singh, 2023, Integrative Medicine Reports.

Recent development in targeting PI3K-Akt-mTOR signaling for anticancer therapeutic strategies.

Shakir Ali, A. Qazi, A. Hussain, 2013, Anti-cancer agents in medicinal chemistry.

A convergent synthesis of novel alkyne–azide cycloaddition congeners of betulinic acid as potent cytotoxic agent

Shashank K Singh, S. Rath, P. Sangwan, 2017, Steroids.

In-vitro cytotoxicity in relation to chemotypic diversity in diploid and tetraploid populations of Gentiana kurroo Royle.

S. Lattoo, A. Gupta, S. Jeelani, 2021, Journal of ethnopharmacology.

Dendrimer encapsulated and conjugated delivery of berberine: A novel approach mitigating toxicity and improving in vivo pharmacokinetics.

M. P. Khinchi, Shashank K Singh, U. Gupta, 2017, International journal of pharmaceutics.

A new clerodane furano diterpene glycoside from Tinospora cordifolia triggers autophagy and apoptosis in HCT-116 colon cancer cells.

Ashok Kumar, Shashank K Singh, R. Vishwakarma, 2018, Journal of ethnopharmacology.

Development and evaluation of paclitaxel loaded PLGA:poloxamer blend nanoparticles for cancer chemotherapy.

S. Jain, Shashank K Singh, A. Saneja, 2014, International journal of biological macromolecules.

Interaction of natural products with cell survival and signaling pathways in the biochemical elucidation of drug targets in cancer.

A. Qazi, A. Hussain, Shashank K Singh, 2011, Future oncology.

Development and evaluation of folate functionalized albumin nanoparticles for targeted delivery of gemcitabine.

P. R. Sharma, Shashank K Singh, D. Mondhe, 2015, International journal of pharmaceutics.

Synthesis of novel benzylidene analogues of betulinic acid as potent cytotoxic agents.

Shashank K Singh, P. Sangwan, S. Rath, 2017, European journal of medicinal chemistry.

Combined effect of microRNA, nutraceuticals and drug on pancreatic cancer cell lines.

Shashank K Singh, S. Vaishnavi, R. Bamezai, 2015, Chemico-biological interactions.

Synthesis, characterization and mechanistic-insight into the anti-proliferative potential of PLGA-gemcitabine conjugate.

Shashank K Singh, A. Saxena, Deepika Singh, 2014, International journal of pharmaceutics.

Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.

Shakir Ali, A. Qazi, A. Hussain, 2015, Cancer letters.

In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells.

S. Bhushan, Shashank K Singh, A. Saxena, 2008, Chemico-biological interactions.

Synthesis and biological evaluation of novel bavachinin analogs as anticancer agents.

A. Raina, Shashank K Singh, P. Sangwan, 2018, European journal of medicinal chemistry.

A propionyloxy derivative of 11-keto-β-boswellic acid induces apoptosis in HL-60 cells mediated through topoisomerase I & II inhibition.

Shashank K Singh, S. C. Taneja, B. A. Shah, 2011, Chemico-biological interactions.

In silico evaluation of the resistance of the T790M variant of epidermal growth factor receptor kinase to cancer drug Erlotinib

V. Uversky, Shashank K Singh, I. Singh, 2018, Journal of biomolecular structure & dynamics.

Immunostimulatory activity of plumieride an iridoid in augmenting immune system by targeting Th‐1 pathway in balb/c mice

Shashank K Singh, A. Hamid, N. Satti, 2017, International immunopharmacology.

1,2,3-Triazole Tethered Hybrid Capsaicinoids as Antiproliferative Agents Active against Lung Cancer Cells (A549)

Shashank K Singh, S. Parveen, B. Lone, 2022, ACS omega.

In Silico Evaluation of Variable pH on the Binding of Epidermal Growth Factor Receptor Ectodomain to its Ligand Through Molecular Dynamics Simulation in Tumors

Gurvinder Singh, I. Singh, V. Verma, 2019, Interdisciplinary Sciences Computational Life Sciences.

Chitosan Engineered PAMAM Dendrimers as Nanoconstructs for the Enhanced Anti-Cancer Potential and Improved In vivo Brain Pharmacokinetics of Temozolomide

Ajazuddin, Shashank K Singh, U. Gupta, 2018, Pharmaceutical Research.

Penicillium spp.: prolific producer for harnessing cytotoxic secondary metabolites

Shashank K Singh, Mytre Koul, Shashank K. Singh, 2017, Anti-cancer drugs.

Holistic Molecular Approaches for Anticancer Therapy

Shashank K Singh, A. Saxena, G. Chashoo, 2012 .

Isolation, Anticancer Evaluation, Molecular Docking, Drug likeness and ADMET Studies of Secondary Metabolites from Psoralea corylifolia seeds

Shashank K Singh, P. Sangwan, A. Qayum, 2022, ChemistrySelect.

Anticancer Activity of Cordia dichotoma against a Panel of Human Cancer Cell Lines and Their Phytochemical Profiling via HPLC and GCMS

Talal A. Zari, Shashank K Singh, Vikas Sharma, 2022, Molecules.

Isolation of isoxanthanol and synthesis of novel derivatives as potential cytotoxic agents

Shashank K Singh, S. Koul, P. Sangwan, 2017, Medicinal Chemistry Research.

Enhanced Algal Biomass Production in a Novel Electromagnetic Photobioreactor (E-PBR)

S. Sasmal, Y. Kumar, Shashank K. Singh, 2022, Current Microbiology.

Site-Selective Synthesis of C-17 Ester Derivatives of Natural Andrographolide for Evaluation as a Potential Anticancer Agent

Shashank K Singh, Davinder Singh, R. Shankar, 2023, ACS omega.

Long-circulatory nanoparticles for gemcitabine delivery: Development and investigation of pharmacokinetics and in-vivo anticancer efficacy.

Shashank K Singh, A. Saxena, D. Mondhe, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Isolation, identification and bioactive potential of bacterial endophytes from Coleus

A. Chaubey, Shashank K Singh, Sumit G. Gandhi, 2019 .

PARP cleavage and perturbance in mitochondrial membrane potential by 3-α-propionyloxy-β-boswellic acid results in cancer cell death and tumor regression in murine models.

P. R. Sharma, Shashank K Singh, S. C. Taneja, 2012, Future oncology.

Modulation of glycolysis and lipogenesis by novel PI3K selective molecule represses tumor angiogenesis and decreases colorectal cancer growth.

Shashi Bhushan, Santosh Kumar Guru, P. R. Sharma, 2016, Cancer letters.

Improved efficacy of cisplatin in combination with a nano-formulation of pentacyclic triterpenediol.

Shashank K Singh, Ashok Kumar, N. Alam, 2016, Materials science & engineering. C, Materials for biological applications.

Reduced toxicological manifestations of cisplatin following encapsulation in folate grafted albumin nanoparticles.

Shashank K Singh, Ashok Kumar, R. Dubey, 2015, Life sciences.

Design, synthesis and anticancer activity of Michael-type thiol adducts of α-santonin analogue with exocyclic methylene.

Shashank K Singh, R. Vishwakarma, L. Pilcher, 2015, European journal of medicinal chemistry.

Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs.

Shashank K Singh, S. C. Taneja, B. A. Shah, 2012, Bioorganic & medicinal chemistry letters.

Isolation, Cytotoxicity Evaluation, Docking, ADMET and Drug Likeness Studies of Secondary Metabolites from the Stem Bark of Anthocephalus cadamba (Roxb.)

Shashank K Singh, P. Sangwan, A. Qayum, 2022, ChemistrySelect.

Design and synthesis of highly oxygenated furo[3,2‐c]pyran‐4‐ones and furo[3,2‐c]chromen‐4‐ones scaffold as anticancer and antimicrobial agents

Shashank K Singh, P. Sangwan, Devinder Kumar, 2021, Journal of Heterocyclic Chemistry.

Genotoxicity and immunotoxic effects of 1,2-dichloroethane in Wistar rats

A. Hussain, Shashank K Singh, W. Ahmad, 2016, Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews.

Naphthoflavones as Antiproliferative Agents: Design, Synthesis and Biological Evaluation.

Dinesh Kumar, Onkar Singh, Shashank K Singh, 2016, Anti-cancer agents in medicinal chemistry.

4-aryl/heteroaryl-4H-fused Pyrans as Anti-proliferative Agents: Design, Synthesis and Biological Evaluation.

Dinesh Kumar, Shashank K Singh, D. Mondhe, 2018, Anti-cancer agents in medicinal chemistry.

Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells

G. Bifulco, A. Chaubey, Shashank K Singh, 2020, ACS omega.

Crystal Structure, quantum chemical analysis and apoptotic propensity of diaryl substituted α-aminophosphonates as selected C P bonded systems

A. Qayum, Azaj Ansari, Oval Yadav, 2023, Polyhedron.

Secondary Metabolites from Endophytic Fungus Penicillium pinophilum Induce ROS-Mediated Apoptosis through Mitochondrial Pathway in Pancreatic Cancer Cells

P. R. Sharma, Ashok Kumar, A. Chaubey, 2016, Planta Medica.

2-Pyridin-4-yl-methylene-beta-boswellic Acid-A Potential Candidate for Targeting O6-Methylguanine-DNA Methyltransferase Epi-transcriptional Reprogramming in KRAS G13D-Microsatellite Stable, G12V-Microsatellite Instable Mutant Colon Cancer.

B. A. Shah, Ruchi Malik, S. Srivastava, 2022, ACS pharmacology & translational science.

Synergistic combination of PMBA and 5-fluorouracil (5-FU) in targeting mutant KRAS in 2D and 3D colorectal cancer cells

Shashank K Singh, B. A. Shah, Utpal Nandi, 2022, Heliyon.

An investigation of in vitro cytotoxicity and apoptotic potential of aromatic diselenides.

S. Bhushan, Shashank K Singh, B. A. Shah, 2014, Bioorganic & medicinal chemistry letters.

Synthesis of β-boswellic acid derivatives as cytotoxic and apoptotic agents.

P. R. Sharma, Shashank K Singh, B. A. Shah, 2016, Bioorganic & medicinal chemistry letters.

Serine‐glycine‐betaine, a novel dipeptide from an endophyte Macrophomina phaseolina: isolation, bioactivity and biosynthesis

Shashank K Singh, V. Singamaneni, M. Katoch, 2021, Journal of applied microbiology.

Effect of acetyl 11-keto beta-boswellic acid on metastatic growth factor responsible for angiogenesis.

Shashank K Singh, A. Saxena, D. Mondhe, 2007, Vascular pharmacology.

Chemically standardized isolates from Cedrus deodara stem wood having anticancer activity.

Shashank K Singh, A. Saxena, D. Mondhe, 2007, Planta medica.

Potential role of natural molecules in health and disease: importance of boswellic acid.

Shashank K Singh, A. Saxena, A. Hamid, 2010 .

Insights into the Role of Defective Apoptosis in Cancer Pathogenesis and Therapy

Sonia Thapa, Rafiq A. Rather, Shashank K. Singh, 2021, Regulation and Dysfunction of Apoptosis [Working Title].

Synthesis of 1,2,4-oxadiazole derivatives: anticancer and 3D QSAR studies

Shashank K Singh, Shweta Jain, Ankur Vaidya, 2020, Monatshefte für Chemie - Chemical Monthly.

Transferrin-appended PEGylated nanoparticles for temozolomide delivery to brain: in vitro characterisation

A. Saxena, Sanjay K. Jain, Aviral Jain, 2011, Journal of microencapsulation.

Empagliflozin containing chitosan-alginate nanoparticles in orodispersible film: preparation, characterization, pharmacokinetic evaluation and its in-vitro anticancer activity

Shashank K Singh, Sonali, R. Dutt, 2022, Drug development and industrial pharmacy.

Antimicrobial and Cytotoxic Potential of Helminthosporin from Rumex abyssiniscus Jacq. Discovered as a Novel Source of Syringic Acid and Bis(2-ethyloctyl) Phthalate

Shashank K Singh, S. Bharate, Sumit G. Gandhi, 2022, Current Microbiology.

Synthesis, Biological Activity and Molecular Docking Studies of Heterocyclic Chalcones

Shashank K Singh, P. Sangwan, Devinder Kumar, 2022, Chemistry & biodiversity.

Vitamin E TPGS based palatable, oxidatively and physically stable emulsion of microalgae DHA oil for infants, children and food fortification

Narpinder Singh, S. Jain, U. Gupta, 2020, Journal of Dispersion Science and Technology.

In silico evaluation of the resistance of the T790M variant of epidermal growth factor receptor kinase to cancer drug Erlotinib

V. Uversky, I. Singh, V. Verma, 2018, Journal of biomolecular structure & dynamics.

Secondary Metabolites from Endophytic Fungus Penicillium pinophilum Induce ROS-Mediated Apoptosis through Mitochondrial Pathway in Pancreatic Cancer Cells

Ashok Kumar, A. Chaubey, A. Hamid, 2016, Planta Medica.

Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells

P. R. Sharma, Ashok Kumar, Shashank K Singh, 2017, BMC Cell Biology.

Diversity, Phylogeny, anticancer and antimicrobial potential of fungal endophytes associated with Monarda citriodora L.

S. Singh, M. Katoch, Shipra Phull, 2017, BMC Microbiology.

A new clerodane furano diterpene glycoside from Tinospora cordifolia triggers autophagy and apoptosis in HCT-116 colon cancer cells.

Ashok Kumar, R. Vishwakarma, M. Verma, 2018, Journal of ethnopharmacology.

Chitosan Engineered PAMAM Dendrimers as Nanoconstructs for the Enhanced Anti-Cancer Potential and Improved In vivo Brain Pharmacokinetics of Temozolomide

Ajazuddin, U. Gupta, A. Sharma, 2018, Pharmaceutical Research.

PARP cleavage and perturbance in mitochondrial membrane potential by 3-α-propionyloxy-β-boswellic acid results in cancer cell death and tumor regression in murine models.

S. C. Taneja, B. A. Shah, A. Saxena, 2012, Future oncology.

Biodegradable nano-architectural PEGylated approach for the improved stability and anticancer efficacy of bendamustine.

Shashank K Singh, U. Gupta, A. Sharma, 2016, International journal of biological macromolecules.

Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents.

Shashank K Singh, S. C. Taneja, A. Saxena, 2011, European journal of medicinal chemistry.

Development and characterization of hyaluronic acid modified PLGA based nanoparticles for improved efficacy of cisplatin in solid tumor.

D. Mondhe, Rahul Gupta, N. Alam, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

A novel PI3K axis selective molecule exhibits potent tumor inhibition in colorectal carcinogenesis

Ashok Kumar, A. Qazi, A. Hussain, 2016, Molecular carcinogenesis.

Carbohydrate Modifications of Neoandrographolide for Improved Reactive Oxygen Species-Mediated Apoptosis through Mitochondrial Pathway in Colon Cancer

S. Kaul, M. Dhar, Ajeet Singh, 2019, ACS omega.

Development and evaluation of paclitaxel loaded PLGA:poloxamer blend nanoparticles for cancer chemotherapy.

S. Jain, A. Saneja, R. Dubey, 2014, International journal of biological macromolecules.

Synthesis of 3-N-/O-/S-methyl-imidazo[1,2-a] pyridine derivatives for caspase-3 mediated apoptosis induced anticancer activity.

Shashank K Singh, A. Nargotra, A. Samykutty, 2022, Bioorganic chemistry.

In Silico Evaluation of Variable pH on the Binding of Epidermal Growth Factor Receptor Ectodomain to its Ligand Through Molecular Dynamics Simulation in Tumors

Gurvinder Singh, I. Singh, V. Verma, 2017, Interdisciplinary Sciences: Computational Life Sciences.

Synthesis of 14-deoxy-benzylidene-8,17-epoxy-diene-andrographolide derivatives and evaluation of their anticancer activities

Shashank K Singh, S. Kaul, M. Dhar, 2022, Journal of the Indian Chemical Society.