P. Meyts

发表

β-Adrenergic receptors: Evidence for negative cooperativity

Robert J. Lefkowitz, R. Lefkowitz, L. Limbird, 1975 .

The Hypoglycemic Effect of a Sulfonylurea (gliclazide) in Moderate Type-ii Diabetes and Glucose-intolerance Is Not Accompanied By Changes in Insulin Action and Insulin Binding To Erythrocytes

F. Grigorescu, J. Ketelslegers, M. Buysschaert, 1983 .

How Insulin Binds: the B-Chain α-Helix Contacts the L1 β-Helix of the Insulin Receptor

M. Weiss, Biaoru Li, J. Whittaker, 2004 .

Insulin and its receptor: structure, function and evolution.

P. D. Meyts, Pierre De Meyts, P. Meyts, 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.

Structural biology of insulin and IGF1 receptors: implications for drug design

J. Whittaker, P. D. Meyts, P. Meyts, 2002, Nature Reviews Drug Discovery.

The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling

P. D. Meyts, P. Meyts, 1994, Diabetologia.

Insulin and IGF-I Receptor Structure and Binding Mechanism

L. Gauguin, J. Whittaker, Waseem Sajid, 2007 .

Structure-Function Relationships of Insulin and Insulin-Like Growth factor-I Receptor Binding

J. Whittaker, P. D. Meyts, P. Meyts, 2002 .

M. Federwisch, M. Dieken, P. D. Meyts, 2002, Springer Netherlands.

Gene Expression Profiling of Human Adipocyte Responses to Insulin and IGF-I Signalling

K. O'Byrne, H. Tornqvist, S. Gray, 2009 .

Beta-adrenergic receptors: evidence for negative cooperativity.

R. Lefkowitz, L. Limbird, P. D. Meyts, 1975, Biochemical and biophysical research communications.

Insulin/receptor binding: The last piece of the puzzle?

P. D. Meyts, P. Meyts, 2015 .

The insulin receptor: a prototype for dimeric, allosteric membrane receptors?

P. D. Meyts, P. Meyts, 2008 .

Mapping of the residues responsible for the negative cooperativity of the receptor-binding region of insulin

E. Obberghen, J. Roth, A. Wollmer, 1978, Nature.

The Insulin-Like Growth Factor-I Receptor

B. Ursø, C. Christoffersen, K. Grønskov, 1994, Hormone Research.

Receptor Oligomerization in Family B1 of G-Protein-Coupled Receptors: Focus on BRET Investigations and the Link between GPCR Oligomerization and Binding Cooperativity

Rasmus Jorgensen, P. D. Meyts, Sarah Norklit Roed, 2012, Front. Endocrin..

The Mechanism of Insulin Receptor Binding, Activation and Signal Transduction

K. Seedorf, P. D. Meyts, P. Meyts, 1997 .

Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor

C. Christoffersen, R. Shymko, D. Naor, 1997, Diabetologia.

Mitogenic and Antiadipogenic Properties of Human Growth Hormone in Differentiating Human Adipocyte Precursor Cells in Primary Culture1

M. Wabitsch, H. Hauner, R. Shymko, 1996, Pediatric Research.

Receptor Tyrosine Kinase Signal Transduction and the Molecular Basis of Signalling Specificity

P. D. Meyts, P. Meyts, 2015 .

Structural Conservation of Insulin/IGF Signalling Axis at the Insulin Receptors Level in Drosophila and humans

A. Brzozowski, Talha Shafi, H. Jenkins, 2023, bioRxiv.

Cooperative Regulation of Hormone Binding Affinity for Cell Surface Receptors

P. Meyts, 1976 .

Insulin receptors and insulin action

C. Christoffersen, H. Tornqvist, K. Seedorf, 1996 .

Cooperative properties of hormone receptors in cell membranes.

P. Meyts, 1976 .

Biological effects of human growth hormone in rat adipocyte precursor cells and newly differentiated adipocytes in primary culture.

M. Wabitsch, H. Hauner, P. De Meyts, 1996, Metabolism: clinical and experimental.

Insulin-dependent regulation of insulin receptor concentrations: a direct demonstration in cell culture.

D. Neville, J. Roth, P. De Meyts, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Engineering the C-region of human insulin-like growth factor-1: implications for receptor binding.

B. Ursø, J. Pitts, J. Murray-Rust, 1996, Protein engineering.

Negative cooperativity in the insulin-like growth factor-I receptor and a chimeric IGF-I/insulin receptor.

C. Christoffersen, N. Heisterkamp, J. Groffen, 1994, Endocrinology.

The Insulin-Like Growth Factor-I Receptor

B. Ursø, C. Christoffersen, K. Grønskov, 1994 .

Insulin interactions with its receptors: experimental evidence for negative cooperativity.

D. Neville, J. Roth, P. De Meyts, 1973, Biochemical and biophysical research communications.

Genetic engineering in mice: impact on insulin signalling and action.

A. Baudry, B. Lamothe, R. Joshi, 1998, The Biochemical journal.

Negative cooperativity in H2 relaxin binding to a dimeric relaxin family peptide receptor 1

J. Wade, J. Nøhr, M. Vrecl, 2008, Molecular and Cellular Endocrinology.

Early Recombinant Protein Therapeutics

P. D. Meyts, P. Meyts, 2017 .

Insulin and insulin-like growth factors: the paradox of signaling specificity.

P. Meyts, 2002 .

EFFECTS OF STARVATION, REFEEDING, AND DIETING

C. Kahn, J. Roth, P. Gorden, 1976 .

Comparison of the effects of hypertonic sucrose and intracellular potassium depletion on growth hormone receptor binding kinetics and down-regulation in IM-9 cells: evidence for a sequential block of receptor--mediated endocytosis.

P. Courtoy, P. De Meyts, M. Ilondo, 1991, Endocrinology.

Monoclonal Antibodies Against Growth Hormone: Effects on the Hormone Interaction with Specific Cell Surface Receptors

P. Masson, L. Retegui, P. Meyts, 1982 .

Receptor Activation by Antigens, Cytokines, Hormones and Growth Factors

J. Schlessinger, M. Feldmann, D. Naor, 1995 .

Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans

A. Brzozowski, Talha Shafi, H. Jenkins, 2023, bioRxiv.

Structure of growth hormone and its receptor: an unexpected stoichiometry.

P. D. Meyts, P. Meyts, 1992 .

Cooperativity in ligand binding: a new graphic analysis.

J. Roth, P. De Meyts, P. Meyts, 1975, Biochemical and biophysical research communications.

The diabetogenes concept of NIDDM.

P. D. Meyts, P. Meyts, 1993 .

Fluctuations in the affinity and concentration of insulin receptors on circulating monocytes of obese patients: effects of starvation, refeeding, and dieting.

C. Kahn, J. Roth, P. Gorden, 1976, The Journal of clinical investigation.

Immunological and Metabolic Responses of Patients with History of Antibody-Induced Beef Insulin Resistance to Treatment With Beef, Pork, Human, and Sulfated Beef Insulin

N. Fineberg, S. Fineberg, J. Galloway, 1992, Diabetes Care.

The insulin-like growth factors and insulin-signalling systems: an appealing target for breast cancer therapy?

P. De Meyts, S. Gray, I. S. Mathiasen, 2003, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

The Insulin Receptor and Its Signal Transduction Network

P. D. Meyts, P. Meyts, 2016 .

Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions

C. Kahn, R. DiMarchi, Weikang Cai, 2018, Proceedings of the National Academy of Sciences.