Juan F. González

发表

Developments with multi-target drugs for Alzheimer’s disease: an overview of the current discovery approaches

J. Sánchez-montero, A. Alcántara, A. Doadrio, 2019, Expert opinion on drug discovery.

Functionalization of Morin-Loaded PLGA Nanoparticles with Phenylalanine Dipeptide Targeting the Brain

E. Barcia, L. García-García, A. Fernández-Carballido, 2022, Pharmaceutics.

Three-Component Synthesis of a Library of m-Terphenyl Derivatives with Embedded β-Aminoester Moieties.

J. Menéndez, Víctor González-Ruiz, V. Sridharan, 2018, ACS combinatorial science.

Synthesis of novel (NHC)Pd(acac)Cl complexes (acac=acetylacetonate) and their activity in cross-coupling reactions

S. Nolan, O. Navarro, Natalie M. Scott, 2005 .

Neuroprotective mechanisms of multitarget 7-aminophenanthridin-6(5H)-one derivatives against metal-induced amyloid proteins generation and aggregation.

J. Menéndez, N. Rosales-Conrado, J. D. Pino, 2022, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Neuroprotective Action of Multitarget 7-Aminophenanthridin-6(5H)-one Derivatives against Metal-Induced Cell Death and Oxidative Stress in SN56 Cells

J. Menéndez, N. Rosales-Conrado, Paula Moyano, 2021, ACS chemical neuroscience.

Discovery of 7-aminophenanthridin-6-one as a new scaffold for matrix metalloproteinase inhibitors with multitarget neuroprotective activity.

J. Menéndez, Mariangela Agamennone, N. Rosales-Conrado, 2020, European journal of medicinal chemistry.

Pyrazino[1,2-b]isoquinolines: synthesis and study of their cytostatic and cytotoxic properties.

C. Avendaño, R. Perona, C. Manguán-García, 2008, Bioorganic & medicinal chemistry.

Privileged scaffolds in synthesis: 2,5-piperazinediones as templates for the preparation of structurally diverse heterocycles.

Juan F. González, Irene Ortín, Elena de la Cuesta, 2012, Chemical Society reviews.

Synthesis of tetramic acids with a benzo[ f ]indolizine skeleton. Transannular rearrangements in pyrazino[1,2- b ]isoquinolin-4-ones

C. Avendaño, Irene Ortín, Juan F González, 2010 .

Cytotoxicity of new pyrazino[1,2-b]isoquinoline and 6,15-iminoisoquino[3,2-b]3-benzazocine compounds.

C. Avendaño, Irene Ortín, E. de la Cuesta, 2010, Bioorganic & medicinal chemistry.

Reactions promoted by [hydroxy(tosyloxy)iodo]benzene in pyrazino[1,2–b]isoquinolines

C. Avendaño, Irene Ortín, Juan F González, 2010 .

Cytotoxicity mechanisms of pyrazino[1,2-b]isoquinoline-4-ones and SAR studies.

C. Avendaño, R. Perona, C. Manguán-García, 2009, Bioorganic & medicinal chemistry.

C(3)-alkylation and cyclization of pyrazino[1,2-b]isoquinolin-4-ones

C. Avendaño, Irene Ortín, Juan F González, 2009 .

Synthesis of a novel tetrahydroisoquinoline pentacyclic framework

C. Avendaño, Irene Ortín, Juan F González, 2009 .

Improvements in Aldol Reactions with Diketopiperazines

C. Avendaño, Juan F González, E. de la Cuesta, 2004 .

Pictet Spengler-type reactions in 3-arylmethylpiperazine-2,5-diones. Synthesis of pyrazinotetrahydroisoquinolines

C. Avendaño, Juan F González, E. Cuesta, 2004 .

Short stereocontrolled synthesis of trans and cis-tetrahydro-pyrazinoisoquinolinediones

C. Avendaño, Juan F González, E. Cuesta, 2003 .

Synthesis and cytotoxic activity of pyrazino[1,2-b]-isoquinolines, 1-(3-isoquinolyl)isoquinolines, and 6,15-iminoisoquino[3,2-b]-3-benzazocines.

C. Avendaño, Juan F González, E. de la Cuesta, 2007, Bioorganic & medicinal chemistry.

Benign synthesis of therapeutic agents: domino synthesis of unsymmetrical 1,4-diaryl-1,4-dihydropyridines in the ball-mill

J. Menéndez, A. Porcheddu, E. Colacino, 2022, Green Chemistry Letters and Reviews.

m-Terphenylamines, Acting as Selective COX-1 Inhibitors, Block Microglia Inflammatory Response and Exert Neuroprotective Activity

R. J. Doerksen, J. Menéndez, M. Perrone, 2023, Molecules.

A sequential multistep process for the fully mechanochemical, one-pot synthesis of the antiepileptic drug rufinamide

J. Menéndez, Juan F González, Jorge Gómez-Carpintero, 2022, Green Chemistry Letters and Reviews.

Sustainable Access to Acridin-9-(10H)ones with an Embedded m-Terphenyl Moiety Based on a Three-Component Reaction

J. Menéndez, Juan F González, Jorge Gómez-Carpintero, 2020, Molecules.

One-Pot Synthesis of Functionalized Carbazoles via a CAN-Catalyzed Multicomponent Process Comprising a C-H Activation Step.

J. Menéndez, P. Merino, T. Tejero, 2017, The Journal of organic chemistry.

Ethyl 4,4''-Dibromo-5'-(butylamino)-2',6'-dinitro-(1,1':3',1''- terphenyl)-4'-carboxylate

J. Menéndez, Juan F González, D. Rocchi, 2015 .

Montmorillonite Clay-Promoted, Solvent-Free Cross-Aldol Condensations under Focused Microwave Irradiation

J. Menéndez, Juan F González, D. Rocchi, 2014, Molecules.

Three-component synthesis of highly functionalized aziridines containing a peptide side chain and their one-step transformation into β-functionalized α-ketoamides

J. Menéndez, L. Huck, Juan F González, 2016, Beilstein journal of organic chemistry.