Renato Ferreira de Freitas

发表

Structural biology and chemistry of protein arginine methyltransferases

M. Schapira, R. Ferreira de Freitas, Renato Ferreira de Freitas, 2014, MedChemComm.

A systematic analysis of atomic protein–ligand interactions in the PDB

M. Schapira, R. Ferreira de Freitas, Renato Ferreira de Freitas, 2017, MedChemComm.

Selective, small molecule co-factor binding site inhibition of a Su(var)3-9, Enhancer of Zeste, Trithorax (SET) domain containing lysine methyltransferase.

C. Arrowsmith, M. Schapira, R. Ferreira de Freitas, 2019, Journal of medicinal chemistry.

Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors.

H. Ouyang, C. Arrowsmith, M. Schapira, 2018, Journal of medicinal chemistry.

Methyltransferase Inhibitors: Competing with, or Exploiting the Bound Cofactor

M. Schapira, R. Ferreira de Freitas, D. Ivanochko, 2019, Molecules.

Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.

Matthieu Schapira, Cheryl H Arrowsmith, Peter J Brown, 2016, Journal of medicinal chemistry.

Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.

H. Ouyang, F. von Delft, C. Arrowsmith, 2017, Journal of medicinal chemistry.

Discovery of small molecule antagonists of the USP5 zinc finger ubiquitin-binding domain

C. Arrowsmith, S. Houliston, M. Schapira, 2019, bioRxiv.

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

Matthew J. Meiners, J. Greenblatt, J. Min, 2021, Nature Chemical Biology.

Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.

C. Arrowsmith, M. Schapira, M. Vedadi, 2016, Journal of medicinal chemistry.

Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.

F. von Delft, C. Arrowsmith, M. Schapira, 2017, Journal of medicinal chemistry.