Jérôme Le Nours

发表

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

James McCluskey, Ligong Liu, Zhenjun Chen, 2013, Nature Communications.

Host immunomodulatory lipids created by symbionts from dietary amino acids

J. Rossjohn, Sungwhan F. Oh, D. Kasper, 2021, Nature.

The molecular assembly of the marsupial γμ T cell receptor defines a third T cell lineage

D. Douek, S. Darko, J. Rossjohn, 2021, Science.

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

Spencer J. Williams, J. Rossjohn, D. Pellicci, 2019, Nature Communications.

Molecular recognition of microbial lipid-based antigens by T cells

S. Gras, I. van Rhijn, J. Le Nours, 2018, Cellular and Molecular Life Sciences.

Unconventional T Cell Targets for Cancer Immunotherapy.

J. Rossjohn, D. Godfrey, J. Le Nours, 2018, Immunity.

Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases.

T. Beddoe, J. Rossjohn, J. Vivian, 2010, Structure.

Recognition of the antigen-presenting molecule MR1 by a Vδ3+ γδ T cell receptor

J. Rossjohn, W. Awad, D. Littler, 2021, Proceedings of the National Academy of Sciences.

Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products

J. Rossjohn, R. Cotton, I. van Rhijn, 2020, Science Immunology.

CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells

K. Kedzierska, J. McCluskey, J. Rossjohn, 2022, The Journal of experimental medicine.

Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.

James McCluskey, Ligong Liu, Jamie Rossjohn, 2016, Immunity.

Human skin is colonized by T cells that recognize CD1a independently of lipid.

J. Altman, G. Ogg, B. Pomahac, 2021, The Journal of clinical investigation.

The molecular bases of δ/αβ T cell–mediated antigen recognition

G. Besra, J. McCluskey, J. Rossjohn, 2014, The Journal of experimental medicine.

The structure of endo-beta-1,4-galactanase from Bacillus licheniformis in complex with two oligosaccharide products.

L. Lo Leggio, S. Larsen, J. Le Nours, 2004, Journal of Molecular Biology.

Activity of three β-1,4-galactanases on small chromogenic substrates.

S. Withers, T. Borchert, L. Lo Leggio, 2011, Carbohydrate research.

Investigating the binding of β‐1,4‐galactan to Bacillus licheniformis β‐1,4‐galactanase by crystallography and computational modeling

Sine Larsen, T. Borchert, L. De Maria, 2009, Proteins.

Structure of two fungal β‐1,4‐galactanases: Searching for the basis for temperature and pH optimum

T. Borchert, L. Lo Leggio, S. Larsen, 2003, Protein science : a publication of the Protein Society.

Inhibitor binding in a class 2 dihydroorotate dehydrogenase causes variations in the membrane‐associated N‐terminal domain

E. Johansson, S. Larsen, J. Le Nours, 2004, Protein science : a publication of the Protein Society.

mRNA vaccine against malaria tailored for liver-resident memory T cells

G. McFadden, S. Gras, A. Cozijnsen, 2023, Nature Immunology.

Structure, biological functions and applications of the AB5 toxins.

T. Beddoe, J. Rossjohn, J. Le Nours, 2010, Trends in biochemical sciences.

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.

J. Rossjohn, R. Pryce, S. Porcelli, 2018, Cell chemical biology.

Atypical sideways recognition of CD1a by autoreactive γδ T cell receptors

J. Rossjohn, I. van Rhijn, B. S. Gully, 2022, Nature Communications.

A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins

J. Rossjohn, S. Gras, R. Calderón, 2019, The Journal of Immunology.

Molecular features of lipid-based antigen presentation by group 1 CD1 molecules.

S. Gras, J. Le Nours, A. Shahine, 2017, Seminars in cell & developmental biology.

Atypical natural killer T-cell receptor recognition of CD1d–lipid antigens

G. Besra, J. Rossjohn, S. Gras, 2016, Nature Communications.

A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1

Sri H. Ramarathinam, R. Tothill, J. Sandow, 2019, Science.

EcxAB is a founding member of a new family of metalloprotease AB5 toxins with a hybrid cholera-like B subunit.

T. Beddoe, J. Rossjohn, D. Littler, 2013, Structure.

CD1 and MR1 recognition by human γδ T cells.

I. van Rhijn, J. Le Nours, Jérôme Le Nours, 2021, Molecular immunology.

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

T. Andrews, S. Turner, J. McCluskey, 2020, Science Immunology.

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells

G. Besra, J. Rossjohn, F. Hsu, 2015, The Journal of Immunology.

Quantitative affinity measurement of small molecule ligand binding to major histocompatibility complex class-I–related protein 1 MR1

G. Besra, J. McCluskey, J. Rossjohn, 2022, The Journal of biological chemistry.

Atypical TRAV1-2− T cell receptor recognition of the antigen-presenting molecule MR1

J. McCluskey, J. Rossjohn, D. Fairlie, 2020, The Journal of Biological Chemistry.

Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium tuberculosis Reveal a Novel Bound Nucleotide*

E. Baker, E. M. Bulloch, D. Greenwood, 2011, The Journal of Biological Chemistry.

A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response

J. Rossjohn, S. Gras, D. Pellicci, 2020, Nature Cancer.

The structure and characterization of a modular endo-beta-1,4-mannanase from Cellulomonas fimi.

D. Stoll, L. Lo Leggio, H. Stålbrand, 2005, Biochemistry.

Mucosal‐associated invariant T cell receptor recognition of small molecules presented by MR1

J. McCluskey, J. Rossjohn, L. Kjer-Nielsen, 2018, Immunology and cell biology.

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.

J. Rossjohn, R. Pryce, S. Porcelli, 2018, Cell chemical biology.

The molecular basis underpinning the potency and specificity of MAIT cell antigens

J. McCluskey, J. Rossjohn, D. Fairlie, 2020, Nature Immunology.

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids

Thomas S. Watkins, J. Altman, J. Rossjohn, 2018, Nature Immunology.

T cell receptor recognition of CD1b presenting a mycobacterial glycolipid

J. Rossjohn, S. Gras, I. van Rhijn, 2016, Nature Communications.

Tetrahydrolipstatin Inhibition, Functional Analyses, and Three-dimensional Structure of a Lipase Essential for Mycobacterial Viability*

T. Beddoe, J. Rossjohn, R. Coppel, 2010, The Journal of Biological Chemistry.

Crystal structure of a Legionella pneumophila ecto -triphosphate diphosphohydrolase, a structural and functional homolog of the eukaryotic NTPDases.

T. Beddoe, J. Rossjohn, J. Vivian, 2010, Structure.

Novel Molecular Insights into Human Lipid-Mediated T Cell Immunity

J. Le Nours, M. Wegrecki, A. Shahine, 2021, International journal of molecular sciences.

T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids

Thomas S. Watkins, J. Altman, J. Rossjohn, 2018, Nature Immunology.

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.

J. Rossjohn, R. Pryce, S. Porcelli, 2018, Cell chemical biology.

Investigating the binding of β‐1,4‐galactan to Bacillus licheniformis β‐1,4‐galactanase by crystallography and computational modeling

T. Borchert, L. De Maria, L. Lo Leggio, 2009, Proteins.

The molecular basis underpinning the potency and specificity of MAIT cell antigens

J. McCluskey, J. Rossjohn, D. Fairlie, 2020, Nature Immunology.

Structural Basis of Subtilase Cytotoxin SubAB Assembly*

Matthew D. Johnson, T. Beddoe, J. Rossjohn, 2013, The Journal of Biological Chemistry.