Yufang Xu

发表

Engineering near-infrared laser-activated gold nanorod vesicles with upper critical solution temperature for photothermal therapy and chemotherapy.

Yufang Xu, Bin Wang, X. Qian, 2023, Journal of colloid and interface science.

Novel benzoyl thioureido benzene sulfonamides as highly potent and selective inhibitors of carbonic anhydrase IX: optimization and bioactive studies.

Honglin Li, Li Liu, Zhenjiang Zhao, 2018, MedChemComm.

Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFRL858R/T790M/C797S.

Xia Wang, Honglin Li, Zhenjiang Zhao, 2019, ACS medicinal chemistry letters.

Discovery of pteridin-7(8H)-one-based irreversible inhibitors targeting the epidermal growth factor receptor (EGFR) kinase T790M/L858R mutant.

Ke Ding, Honglin Li, Wei Zhou, 2013, Journal of medicinal chemistry.

Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR

Tao Zhang, Xia Wang, Honglin Li, 2019 .

Fluorescence properties and antiproliferative effects of mono-, bis-, and tris- thiophenylnaphthalimides: results of a comparative pilot study.

Yufang Xu, X. Qian, I. Ott, 2011, Journal of photochemistry and photobiology. B, Biology.

3B, a novel photosensitizer, inhibits glycolysis and inflammation via miR-155-5p and breaks the JAK/STAT3/SOCS1 feedback loop in human breast cancer cells.

Yufang Xu, Jianwen Liu, Xin Liang, 2016, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

7b, a novel amonafide analog, inhibited proliferation and phorbol 12-myristate 13-acetate/phytohemagglutinin-induced inflammatory responses of Jurkat T cells via p73-dependent pathway and decrease of nuclear factor-κB DNA-binding, respectively

Yufang Xu, Jianwen Liu, X. Qian, 2013, Leukemia & lymphoma.

Design, Synthesis, and Biological Evaluation of Pyrimido[4,5- d]pyrimidine-2,4(1 H,3 H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation.

Honglin Li, Jiankun Lyu, Zhenjiang Zhao, 2018, Journal of medicinal chemistry.

A gold(I) phosphine complex containing a naphthalimide ligand functions as a TrxR inhibiting antiproliferative agent and angiogenesis inhibitor.

Yufang Xu, C. Bagowski, Inês J. Marques, 2009, Journal of medicinal chemistry.

A dual pH and temperature responsive polymeric fluorescent sensor and its imaging application in living cells.

Yufang Xu, Weiping Zhu, Yufang Xu, 2012, Chemical communications.

Discovery and optimization of 4-anilinoquinazoline derivatives spanning ATP binding site and allosteric site as effective EGFR-C797S inhibitors.

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2022, European journal of medicinal chemistry.

A highly sensitive fluorescent probe for tracking intracellular zinc ions and direct imaging of prostatic tissue in mice

Yufang Xu, X. Qian, Weiping Zhu, 2020 .

Efficient induction of ginsenoside biosynthesis and alteration of ginsenoside heterogeneity in cell cultures of Panax notoginseng by using chemically synthesized 2-hydroxyethyl jasmonate

Zhenjiang Zhao, Yufang Xu, X. Qian, 2006, Applied Microbiology and Biotechnology.

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells.

Yufang Xu, X. Qian, Weiping Zhu, 2012, Chemical communications.

A colorimetric sensor for Cu2+ in aqueous solution based on metal ion-induced deprotonation: deprotonation/protonation mediated by Cu2+-ligand interactions.

Yufang Xu, X. Qian, Junhai Huang, 2009, Dalton transactions.

Phenylboronic acid functionalized silica nanoparticles with enlarged ordered mesopores for efficient insulin loading and controlled release

Yufang Xu, Weiping Zhu, Mingyang Hei, 2019, Journal of Drug Delivery Science and Technology.

A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers.

Yufang Xu, Chusen Huang, Yunfeng Lu, 2012, Chemical communications.

Micelle-induced versatile performance of amphiphilic intramolecular charge-transfer fluorescent molecular sensors.

Yufang Xu, X. Qian, Junhong Qian, 2007, Chemistry.

A DPA-based highly selective and sensitive fluorescent probe for mercuric ions and its imaging in living cells.

Yufang Xu, Chusen Huang, X. Qian, 2016, Dalton transactions.

A highly sensitive and selective OFF-ON fluorescent sensor for cadmium in aqueous solution and living cell.

Weiping Zhu, Yufang Xu, Liping Duan, 2008, Journal of the American Chemical Society.

A Water-Soluble Copper(II) Complex for the Selective Fluorescence Detection of Nitric Oxide/Nitroxyl and Imaging in Living Cells.

Yufang Xu, Juyoung Yoon, T. James, 2016, ChemPlusChem.

Highly sensitive and selective ratiometric fluorescent copper sensors: Different binding affinities modulated by three separate side chains of naphthalimide

Yufang Xu, Zhaochao Xu, X. Qian, 2009 .

Photolarvicidal effect of thienyl 1,3,4-thia(oxa)diazoles and their potential DNA photocleavage

Yufang Xu, X. Qian, Ciying Xiao, 2004 .

A small molecular fluorescent sensor functionalized silica microsphere for detection and removal of mercury, cadmium, and lead ions in aqueous solutions

Yufang Xu, X. Qian, Weiping Zhu, 2015 .

A highly selective heterogeneous fluorescent sensor for palladium ions

Yufang Xu, X. Qian, Weiping Zhu, 2015 .

Naphthalimides and analogues as antitumor agents: A review on molecular design, bioactivity and mechanism of action

Yufang Xu, X. Qian, Zhuo Chen, 2018, Chinese Chemical Letters.

"Alive" dyes as fluorescent sensors: fluorophore, mechanism, receptor and images in living cells.

Yufang Xu, X. Qian, Junhong Qian, 2010, Chemical communications.

Induction of G2/M phase arrest and apoptosis by potent antitumor APCA in human cervix carcinoma cells

Yufang Xu, F. Wang, Jianwen Liu, 2011, Anti-cancer drugs.

Thio-bisnaphthalimides as Heavy-Atom-Free Photosensitizers with Efficient Singlet Oxygen Generation and Large Stokes Shifts: Synthesis and Properties.

Yufang Xu, Jianwen Liu, X. Qian, 2016, Organic letters.

One small molecule as a theranostic agent: naphthalimide dye for subcellular fluorescence localization and photodynamic therapy in vivo

Yufang Xu, Jianwen Liu, X. Qian, 2016 .

Rhodamine-based fluorescent off-on sensor for Fe3+--in aqueous solution and in living cells: 8-aminoquinoline receptor and 2:1 binding.

Yufang Xu, X. Qian, Junhai Huang, 2014, Dalton transactions.

pH-Activatable tumor-targeting gold nanoprobe for near-infrared fluorescence/CT dual-modal imaging in vivo.

Yufang Xu, X. Qian, Weiping Zhu, 2019, Colloids and surfaces. B, Biointerfaces.

Discovery and Structural Optimization of N5-Substituted 6,7-Dioxo-6,7-dihydropteridines as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation.

Xia Wang, Honglin Li, Zhenjiang Zhao, 2016, Journal of medicinal chemistry.

Acenaphtho[1,2-b]pyrrole-based selective fibroblast growth factor receptors 1 (FGFR1) inhibitors: design, synthesis, and biological activity.

Honglin Li, Weiping Zhu, Yufang Xu, 2011, Journal of medicinal chemistry.

Highly selective fluorescent chemosensor with red shift for cysteine in buffer solution and its bioimage: symmetrical naphthalimide aldehyde

Yufang Xu, F. Wang, Jianwen Liu, 2008 .

Selective and sensitive chromo- and fluorogenic dual detection of anionic surfactants in water based on a pair of "on-off-on" fluorescent sensors.

Yufang Xu, X. Qian, Junhong Qian, 2009, Chemistry.

Unusual large Stokes shift and solvatochromic fluorophore: Synthesis, spectra, and solvent effect of 6-substituted 2,3-naphthalimide

Yufang Xu, X. Qian, Kishore Baathulaa, 2010 .

A thioether-rich crown-based highly selective fluorescent sensor for Hg(2+) and Ag(+) in aqueous solution.

Yufang Xu, Tao Chen, X. Qian, 2010, Dalton transactions.

Short and scalable synthesis of an anhydride precursor of the environment-sensitive fluorophore 6-dimethylaminonaphthalimide

Yufang Xu, X. Qian, Kishore Baathulaa, 2011, Nature Protocols.

Rapid and sensitive fluorescent probes for monoamine oxidases B to A at low concentrations

Yufang Xu, X. Qian, Shaoying Tan, 2012 .

Fragment-based drug design and drug repositioning using multiple ligand simultaneous docking (MLSD): identifying celecoxib and template compounds as novel inhibitors of signal transducer and activator of transcription 3 (STAT3).

David Jou, Yufang Xu, Zhenjiang Zhao, 2011, Journal of medicinal chemistry.

Sulfur-substituted naphthalimides as photoactivatable anticancer agents: DNA interaction, fluorescence imaging, and phototoxic effects in cultured tumor cells.

Yufang Xu, Jianwen Liu, X. Qian, 2008, Bioorganic & medicinal chemistry.

A lysosomal targeting fluorescent probe and its zinc imaging in SH-SY5Y human neuroblastoma cells

Yufang Xu, Chusen Huang, Weiping Zhu, 2019, Chinese Chemical Letters.

Versatile probes for the selective detection of vicinal-dithiol-containing proteins: design, synthesis, and application in living cells.

Yufang Xu, Chusen Huang, X. Qian, 2013, Chemistry.

3B, a novel of photosensitizer, exhibited anti-tumor effects via mitochondrial apoptosis pathway in MCF-7 human breast carcinoma cells

Yufang Xu, Jianwen Liu, Shengchao Lin, 2015, Tumor Biology.

B1, a novel naphthalimide-based DNA intercalator, induces cell cycle arrest and apoptosis in HeLa cells via p53 activation

Yufang Xu, Jianwen Liu, Xin Liang, 2011, Investigational New Drugs.

M(2)-A induces apoptosis and G(2)-M arrest via inhibiting PI3K/Akt pathway in HL60 cells.

Yufang Xu, Jianwen Liu, Aibin Wu, 2009, Cancer letters.

Logically Sensing Aggregate Process and Discriminating SDS from Other Surfactants with the Assistance of BSA

Yufang Xu, X. Qian, Junhong Qian, 2012 .

A highly sensitive, selective ratiometric fluorescent probe for cobalt(II) and its applications for biological imaging.

X. Qian, Weiping Zhu, Shenyi Zhang, 2015, Dalton transactions.

Novel naphthalimide–indomethacin hybrids as potential antitumor agents: effects of linkers on hypoxic/oxic cytotoxicity and apoptosis-inducing activity

Yufang Xu, Aibin Wu, X. Qian, 2010 .

On-demand transdermal insulin delivery system for type 1 diabetes therapy with no hypoglycemia risks.

X. Qian, Congrong Wang, Mengjie Chen, 2021, Journal of colloid and interface science.

5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior.

Yufang Xu, Jianwen Liu, X. Qian, 2011, Bioorganic & medicinal chemistry.

Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship.

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2013, European journal of medicinal chemistry.

7-b, a novel amonafide analogue, cause growth inhibition and apoptosis in Raji cells via a ROS-mediated mitochondrial pathway.

Yufang Xu, Jianwen Liu, X. Qian, 2011, Leukemia research.

Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors

Honglin Li, Jiankun Lyu, Zhenjiang Zhao, 2017, Scientific Reports.

Induction of apoptosis and suppression of ERCC1 expression by the potent amonafide analogue 8-c in human colorectal carcinoma cells

Yufang Xu, Jianwen Liu, Xin Liang, 2013, Anti-cancer drugs.

Salt induced phase separation extraction of 2,3-Butanediol from aqueous solutions: Recovery and recycling of potassium triphosphate

Yufang Xu, S. Si, Afang Liu, 2023, Process Biochemistry.

B1, a Novel Amonafide Analogue, Overcomes the Resistance Conferred by Bcl-2 in Human Promyelocytic Leukemia HL60 Cells

Yufang Xu, Jianwen Liu, Xin Liang, 2010, Molecular Cancer Research.

Cell Cycle , Cell Death , and Senescence B 1 , a Novel Amonafide Analogue , Overcomes the Resistance Conferred by Bcl-2 in Human Promyelocytic Leukemia HL 60 Cells

Yufang Xu, Jianwen Liu, Xin Liang, 2010 .

A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells.

Yufang Xu, X. Qian, Weiping Zhu, 2013, Chemical communications.

Ammonium salt modified mesoporous silica nanoparticles for dual intracellular-responsive gene delivery.

Yufang Xu, X. Qian, Weiping Zhu, 2016, International journal of pharmaceutics.

Rationally designed multitarget anticancer agents.

Yufang Xu, X. Qian, Zhuo Chen, 2013, Current medicinal chemistry.

Effects of anionic surfactant SDS on the photophysical properties of two fluorescent molecular sensors

Yufang Xu, X. Qian, Junhong Qian, 2008 .

Molecular logic operations based on surfactant nanoaggregates.

Junhong Qian, Yufang Xu, Yufang Xu, 2008, Chemphyschem : a European journal of chemical physics and physical chemistry.

Novel nonplanar and rigid fluorophores with intensive emission in water and the application in two-photon imaging of live cells

Yufang Xu, X. Qian, Weiping Zhu, 2016 .

Selective and ratiometric fluorescent trapping and quantification of protein vicinal dithiols and in situ dynamic tracing in living cells.

Yufang Xu, Chusen Huang, Nengqin Jia, 2014, Journal of the American Chemical Society.

A highly selective and sensitive fluorescence "turn-on" probe for Ag+ in aqueous solution and live cells.

X. Qian, Weiping Zhu, Chu‐Ting Yang, 2012, Dalton transactions.

Novel selective and potent inhibitors of malaria parasite dihydroorotate dehydrogenase: discovery and optimization of dihydrothiophenone derivatives.

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2013, Journal of medicinal chemistry.

A highly selective and sensitive near-infrared fluorescence probe for arylamine N-acetyltransferase 2 in vitro and in vivo

Yufang Xu, X. Qian, Weiping Zhu, 2013 .

Dynamic Compartmentalization of Peptide-Oligonucleotide Conjugates with Reversible Nanovesicle-Microdroplet Phase Transition Behaviors.

Yufang Xu, Bin Wang, Yangyang Yang, 2022, ACS applied materials & interfaces.

Self-accelerating H2O2-responsive Plasmonic Nanovesicles for Synergistic Chemo/starving therapy of Tumors

V. Pillay, Y. Choonara, Yufang Xu, 2020, Theranostics.

A reusable heterogeneous catalyst without leaking palladium for highly-efficient Suzuki–Miyaura reaction in pure water under air

Yufang Xu, X. Qian, Weiping Zhu, 2016 .

Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

Yufang Xu, X. Qian, Chunsheng He, 2012 .

The discovery of new scaffold of plant activators: From salicylic acid to benzotriazole

Meijian Sun, Honglin Li, Zhenjiang Zhao, 2017 .

Floro-pyrazolo[3,4-d]pyrimidine derivative as a novel plant activator induces two-pathway immune system.

Zhenjiang Zhao, Yufang Xu, X. Qian, 2021, Phytochemistry.

3(2H)-pyridazinone derivatives: a new scaffold for novel plant activators

Zhenjiang Zhao, Yufang Xu, X. Qian, 2019, RSC advances.

Discovery and optimization of novel plant activators through structure-based virtual screening

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2021 .

Novel plant activators with thieno[2,3-d]-1,2,3-thiadiazole-6-carboxylate scaffold: Synthesis and bioactivity

Zhenjiang Zhao, Yufang Xu, Liao Pengfei, 2013 .

Novel benzo-1,2,3-thiadiazole-7-carboxylate derivatives as plant activators and the development of their agricultural applications.

Zhenjiang Zhao, Yufang Xu, X. Qian, 2012, Journal of agricultural and food chemistry.

Identification of Inhibitors against p90 Ribosomal S6 Kinase 2 (RSK2) through Structure-Based Virtual Screening with the Inhibitor-Constrained Refined Homology Model

Zhenjiang Zhao, Yi Zhou, Jin Huang, 2011, J. Chem. Inf. Model..

SHAFTS: a hybrid approach for 3D molecular similarity calculation. 2. Prospective case study in the discovery of diverse p90 ribosomal S6 protein kinase 2 inhibitors to suppress cell migration.

Hualiang Jiang, Xu Shen, Honglin Li, 2011, Journal of medicinal chemistry.

Tumor Microenvironment-Responsive Hydrogel for Direct Extracellular ATP Imaging-Guided Surgical Resection with Clear Boundaries.

Yangyang Yang, X. Qian, Weiping Zhu, 2023, Advanced healthcare materials.

Discovery of pyrido[3,4-b]indol-1-one derivatives as novel non-covalent Bruton's tyrosine kinase (BTK) inhibitors.

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2021, Bioorganic chemistry.

NCL-based mitochondrial-targeting fluorescent probe for the detection of Glutathione in living cells

Yufang Xu, X. Qian, Dan Wu, 2021, Chinese Chemical Letters.

7b, a novel naphthalimide derivative, exhibited anti-inflammatory effects via targeted-inhibiting TAK1 following down-regulation of ERK1/2- and p38 MAPK-mediated activation of NF-κB in LPS-stimulated RAW264.7 macrophages.

Yufang Xu, Jianwen Liu, X. Qian, 2013, International immunopharmacology.

A turn-on fluorescent probe for tumor hypoxia imaging in living cells.

Yufang Xu, Tao Yu, X. Qian, 2015, Chemical communications.

A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: selective detection and quantification.

Yufang Xu, X. Qian, Weiping Zhu, 2013, Chemical communications.

A dual channel chemodosimeter for Hg2+ and Ag+ using a 1,3-dithiane modified BODIPY

Yufang Xu, X. Qian, Xiaojun Zhang, 2012 .

FRET-Based Mito-Specific Fluorescent Probe for Ratiometric Detection and Imaging of Endogenous Peroxynitrite: Dyad of Cy3 and Cy5.

Yufang Xu, X. Qian, Weiping Zhu, 2016, Journal of the American Chemical Society.

A design concept of long-wavelength fluorescent analogs of rhodamine dyes: replacement of oxygen with silicon atom.

Yufang Xu, Defeng Zhao, X. Qian, 2008, Chemical communications.

Monoarsenical-based chemical approaches for exploration of endogenous vicinal-dithiol-containing proteins (VDPs): From the design to their biological application

Yufang Xu, Chusen Huang, Nengqin Jia, 2020 .

Substituted indolin-2-ones as p90 ribosomal S6 protein kinase 2 (RSK2) inhibitors: Molecular docking simulation and structure-activity relationship analysis.

Honglin Li, Xiaofeng Liu, Mengzhu Xue, 2013, Bioorganic & medicinal chemistry.

Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).

Yufang Xu, Jian Ding, Lin-jiang Tong, 2013, European journal of medicinal chemistry.

Novel seven-membered ring-fused naphthalimide derivatives with potentials for cancer theranostics

Yufang Xu, X. Qian, Weiping Zhu, 2022, Chinese Chemical Letters.

Temperature-sensitive copolymer-coated fluorescent mesoporous silica nanoparticles as a reactive oxygen species activated drug delivery system.

Yufang Xu, X. Qian, Weiping Zhu, 2018, International journal of pharmaceutics.

Design, Synthesis, and Evaluation of Ribose-Modified Anilinopyrimidine Derivatives as EGFR Tyrosine Kinase Inhibitors

Xia Wang, Yufang Xu, Shiliang Li, 2017, Front. Chem..

Discovery and Rational Design of Pteridin-7(8H)-one-Based Inhibitors Targeting FMS-like Tyrosine Kinase 3 (FLT3) and Its Mutants.

Honglin Li, Jiankun Lyu, Zhenjiang Zhao, 2016, Journal of medicinal chemistry.

Discovery of Pteridine-7(8H)-one Derivatives as Potent and Selective Inhibitors of Bruton's Tyrosine Kinase (BTK).

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2022, Journal of medicinal chemistry.

Discovery and biological evaluation of N5-substituted 6,7-dioxo-6,7-dihydropteridine derivatives as potent Bruton's tyrosine kinase inhibitors.

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2018, MedChemComm.

Versatile trifunctional chemosensor of rhodamine derivative for Zn2+, Cu2+ and His/Cys in aqueous solution and living cells.

Yufang Xu, X. Qian, Weiping Zhu, 2011, Organic & biomolecular chemistry.

A novel ratiometric sensor for the fast detection of palladium species with large red-shift and high resolution both in aqueous solution and solid state.

Yufang Xu, X. Qian, Weiping Zhu, 2013, Analytica chimica acta.

Trace mercury (II) detection and separation in serum and water samples using a reusable bifunctional fluorescent sensor.

Weiping Zhu, Yufang Xu, Tao Chen, 2009, Analytica chimica acta.

Modulating the selectivity of near-IR fluorescent probes toward various metal ions by judicious choice of aqueous buffer solutions.

Yufang Xu, Yangyang Yang, X. Qian, 2011, Chemical communications.

Ratiometric and reusable fluorescent nanoparticles for Zn2+ and H2PO4− detection in aqueous solution and living cells

Yufang Xu, Juan Zhou, X. Qian, 2010 .

Oxo-heterocyclic fused naphthalimides as antitumor agents: synthesis and biological evaluation.

Yufang Xu, X. Qian, Zhuo Chen, 2013, European journal of medicinal chemistry.

Novel naphthalimide derivatives as potential apoptosis-inducing agents: design, synthesis and biological evaluation.

Yufang Xu, Jianwen Liu, Aibin Wu, 2009, European journal of medicinal chemistry.

Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studies.

Yufang Xu, F. Wang, Jianwen Liu, 2009, Bioorganic & medicinal chemistry.

Novel cyanine dyes as fluorescent pH sensors: PET, ICT mechanism or resonance effect?

Yufang Xu, X. Qian, Yan Liu, 2007 .

N-aroyloxylthioxo-naphthalimides as DNA photocleavers of aroyloxyl oxygen radicals: synthesis, evaluation, and substituents' effect.

X. Qian, Wei Yao, Xiayu Huang, 2004, Bioorganic & medicinal chemistry.

A new prodrug-derived ratiometric fluorescent probe for hypoxia: high selectivity of nitroreductase and imaging in tumor cell.

Yufang Xu, X. Qian, Weiping Zhu, 2011, Organic letters.

Design, synthesis and structure-activity relationship study of aminopyridine derivatives as novel inhibitors of Janus kinase 2.

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2019, Bioorganic & medicinal chemistry letters.

Studies of Reversible Conjugate Additions

Yufang Xu, E. Anslyn, Ye Zhong, 2013 .

A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network.

Yufang Xu, H. Sugiyama, X. Qian, 2015, Angewandte Chemie.

Design, synthesis and evaluation of PPAR gamma binding activity of 2-thioxo-4-thiazolidinone derivatives

Honglin Li, Xianwen Cao, Mengzhu Xue, 2015 .

A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism

Yufang Xu, X. Qian, T. Cheng, 2016 .

A gold(I) phosphine complex containing a naphthalimide ligand functions as a TrxR inhibiting antiproliferative agent and angiogenesis inhibitor.

C. Bagowski, Inês J. Marques, Danielle H W Vlecken, 2009, Journal of medicinal chemistry.

Selective and sensitive detection and quantification of arylamine N-acetyltransferase 2 by a ratiometric fluorescence probe.

Yufang Xu, X. Qian, Weiping Zhu, 2010, Chemical communications.

In situ visualization and detection of protein sulfenylation responses in living cells through a dimedone-based fluorescent probe.

Yufang Xu, Chusen Huang, X. Qian, 2013, Organic & biomolecular chemistry.

A new class of naphthalimide-based antitumor agents that inhibit topoisomerase II and induce lysosomal membrane permeabilization and apoptosis.

Yufang Xu, Yi Wang, Jianwen Liu, 2010, Journal of medicinal chemistry.

Programmed co-assembly of DNA-peptide hybrid microdroplets by phase separation

Yufang Xu, Yangyang Yang, X. Qian, 2021, Chinese Chemical Letters.

"Alive" dyes as fluorescent sensors: fluorophore, mechanism, receptor and images in living cells.

X. Qian, Junhong Qian, Weiping Zhu, 2010, Chemical communications.

Highly sensitive and selective Pd2+ sensor of naphthalimide derivative based on complexation with alkynes and thio-heterocycle.

Yufang Xu, X. Qian, L. Duan, 2008, Chemical communications.

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells.

X. Qian, Weiping Zhu, Ji Zhou, 2012, Chemical communications.

Engineering naphthalimide-cyanine integrated near-infrared dye into ROS-responsive nanohybrids for tumor PDT/PTT/chemotherapy

Yufang Xu, Haitao Sun, X. Qian, 2021, Bioactive materials.

Highly selective and sensitive near-infrared fluorescent sensors for cadmium in aqueous solution.

Yufang Xu, Yangyang Yang, X. Qian, 2011, Organic letters.

A ratiometric fluorescent probe for fast and sensitive detection of peroxynitrite: a boronate ester as the receptor to initiate a cascade reaction

Yang Li, X. Qian, Rui Wang, 2014 .

Naphthalimides for labeling and sensing applications

Yufang Xu, X. Qian, X. Jia, 2014 .

Novel naphthalimide-amino acid conjugates with flexible leucine moiety as side chain: design, synthesis and potential antitumor activity.

Yufang Xu, Aibin Wu, X. Qian, 2009, Bioorganic & medicinal chemistry.

Red-emission fluorescent probe sensing cadmium and pyrophosphate selectively in aqueous solution.

Yufang Xu, X. Qian, Weiping Zhu, 2011, Organic letters.

A rhodamine-based Hg2+ sensor with high selectivity and sensitivity in aqueous solution: a NS2-containing receptor.

Yufang Xu, X. Qian, Junhai Huang, 2009, The Journal of organic chemistry.

A highly selective space-folded photo-induced electron transfer fluorescent probe for carbonic anhydrase isozymes IX and its applications for biological imaging.

Honglin Li, Weiqiang Lu, Yufang Xu, 2011, Chemical communications.

Highly selective "Off-On" fluorescent probe for histidine and its imaging in living cells.

Yufang Xu, Chusen Huang, X. Qian, 2015, Biosensors & bioelectronics.

A red-shift colorimetric and fluorescent sensor for Cu2+ in aqueous solution: unsymmetrical 4,5-diaminonaphthalimide with N-H deprotonation induced by metal ions.

Yufang Xu, Yufang Xu, X. Qian, 2009, Organic & biomolecular chemistry.

B1-induced caspase-independent apoptosis in MCF-7 cells is mediated by down-regulation of Bcl-2 via p53 binding to P2 promoter TATA box.

Yufang Xu, Jianwen Liu, Xin Liang, 2011, Toxicology and applied pharmacology.

Highly-efficient DNA photocleavers with long wavelength absorptions: thio-heterocyclic fused naphthalimides containing aminoalkyl side chains.

Yufang Xu, X. Qian, Yonggang Li, 2004, Bioorganic & medicinal chemistry letters.

Naphthalimide-thiazoles as novel photonucleases: molecular design, synthesis, and evaluation

Yufang Xu, X. Qian, Yonggang Li, 2004 .

Highly selective, naked-eye and fluorescent "off-on" probe for detection of histidine/histidine-rich proteins and its application in living cell imaging.

Yufang Xu, X. Qian, Weiping Zhu, 2012, Organic & biomolecular chemistry.

Highly sensitive and selective ratiometric fluorescent copper sensors: Different binding affinities modulated by three separate side chains of naphthalimide

Zhaochao Xu, X. Qian, Fengzhu Lu, 2009 .

An “off–on” fluorescent probe for the detection of cysteine /homocysteine and its imaging in living cells

Dan Wu, Yufang Xu, Chusen Huang, 2016 .

Novel nitroheterocyclic hypoxic markers for solid tumor: synthesis and biological evaluation.

Yufang Xu, X. Qian, Weiping Zhu, 2008, Bioorganic & medicinal chemistry.

Versatile Nitro-Fluorophore as Highly Effective Sensor for Hypoxic Tumor Cells: Design, Imaging and Evaluation

Yufang Xu, X. Qian, Weiping Zhu, 2008, Journal of Fluorescence.

Isoindole-1,3-dione derivatives as RSK2 inhibitors: synthesis, molecular docking simulation and SAR analysis

Honglin Li, Weiqiang Lu, Zhenjiang Zhao, 2016 .

Triazole and Benzotriazole Derivatives as Novel Inhibitors for p90 Ribosomal S6 Protein Kinase 2: Synthesis, Molecular Docking and SAR Analysis

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2013 .

Synthesis, activity evaluation, and docking analysis of barbituric acid aryl hydrazone derivatives as RSK2 inhibitors

Honglin Li, Xiaofeng Liu, Weiqiang Lu, 2013, Journal of enzyme inhibition and medicinal chemistry.

Removal of mercury from aqueous solution using mesoporous silica nanoparticles modified with polyamide receptor.

Yufang Xu, L. Ren, X. Qian, 2015, Journal of colloid and interface science.

A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers.

Chusen Huang, Yunfeng Lu, Chunsheng He, 2012, Chemical communications.

Dual-responsive nanohybrid based on degradable silica-coated gold nanorods for triple-combination therapy for breast cancer.

Yufang Xu, X. Qian, Weiping Zhu, 2021, Acta biomaterialia.

Glycopolymer Nanoparticles with On-Demand Glucose-Responsive Insulin Delivery and Low-Hypoglycemia Risks for Type 1 Diabetic Treatment.

Yufang Xu, X. Qian, Mengjie Chen, 2022, Biomacromolecules.

Enzyme/GSH dual-responsive biodegradable nanohybrid for spatiotemporally specific photodynamic and hypoxia-augmented therapy against tumors.

Yufang Xu, X. Qian, Weiping Zhu, 2021, International journal of pharmaceutics.

A hypoxia-activated near infrared fluorescent probe for cyclooxygenase-2 and in vivo imaging for tumor and inflammation

Yufang Xu, Weiping Zhu, Rui Wang, 2018, Sensors and Actuators B: Chemical.

Design, synthesis and SAR study of 2-aminopyridine derivatives as potent and selective JAK2 inhibitors

Honglin Li, Zhenjiang Zhao, Yufang Xu, 2022, Chinese Chemical Letters.

Short intrinsically disordered polypeptide-oligonucleotide conjugates for programmed self-assembly of nanospheres with temperature-dependent size controllability.

Yufang Xu, H. Sugiyama, Bin Wang, 2021, Soft matter.

Programming Rotary Motions with a Hexagonal DNA Nanomachine.

Yufang Xu, H. Sugiyama, C. Fan, 2019, Chemistry.

A Synthetic DNA-Binding Domain Guides Distinct Chromatin-Modifying Small Molecules to Activate an Identical Gene Network.

H. Sugiyama, X. Qian, G. Pandian, 2015, Angewandte Chemie.

Novel aliphatic N-oxide of naphthalimides as fluorescent markers for hypoxic cells in solid tumor.

Yufang Xu, Yuanli Li, Jianwen Liu, 2011, European journal of medicinal chemistry.

Design, synthesis, X-ray crystallographic analysis, and biological evaluation of thiazole derivatives as potent and selective inhibitors of human dihydroorotate dehydrogenase.

Honglin Li, Xiaofeng Liu, Zhenjiang Zhao, 2015, Journal of medicinal chemistry.

Assembly of indole fluorophore in situ for hydrogen sulfide signaling through substrate triggered intramolecular reduction–cyclization cascade: a sensitive and selective probe in aqueous solution

Yuanyuan Luo, Yufang Xu, X. Qian, 2014 .

Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes.

Hualiang Jiang, Honglin Li, Xiaofeng Liu, 2016, Journal of medicinal chemistry.

Abstract 4772: Novel drug discovery approach targeting STAT3 for breast cancer therapy using MLSD and drug repositioning

Li Lin, Zhenjiang Zhao, Yufang Xu, 2012 .

A highly selective and sensitive fluorescence "turn-on" probe for Ag+ in aqueous solution and live cells.

X. Qian, Weiping Zhu, Chu‐Ting Yang, 2012, Dalton transactions.

A ROS-mediated lysosomal-mitochondrial pathway is induced by a novel Amonafide analogue, 7c, in human Hela cervix carcinoma cells.

Yufang Xu, Jianwen Liu, X. Qian, 2013, Cancer letters.

E2F1‐dependent pathways are involved in amonafide analogue 7‐d‐induced DNA damage, G2/M arrest, and apoptosis in p53‐deficient K562 cells

Yufang Xu, Jianwen Liu, X. Qian, 2012, Journal of cellular biochemistry.

Novel fluorescent markers for hypoxic cells of naphthalimides with two heterocyclic side chains for bioreductive binding.

Yufang Xu, Yuanxing Zhang, Jianwen Liu, 2006, Bioorganic & medicinal chemistry.

A pair of regio-isomeric compounds acting as molecular logic gates with different functions

Yufang Xu, X. Qian, Junhong Qian, 2009 .

Unique tri-output optical probe for specific and ultrasensitive detection of hydrazine.

Yufang Xu, Chusen Huang, X. Qian, 2014, Analytical chemistry.

Process parameter and kinetic study for the azidation of a zidovudine intermediate with sodium azide in microreactors

Yufang Xu, M. Shang, Yuanhai Su, 2022, Chemical Engineering Journal.

A novel ‘‘donor-two-acceptor’’ type fluorophore-based probe for fast detection and intracellular imaging of nitroreductase

Yufang Xu, Tao Cheng, X. Qian, 2017 .

Efficient elicitation of ginsenoside biosynthesis in cell cultures ofPanax notoginseng by using self-chemically-synthesized jasmonates

Zhenjiang Zhao, Yufang Xu, X. Qian, 2005 .

Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: synthesis and biological evaluation.

Yufang Xu, X. Qian, H. Yin, 2007, Bioorganic & medicinal chemistry.

Novel Naphthalimide–Benzoic Acid Conjugates as Potential Apoptosis‐Inducing Agents: Design, Synthesis, and Biological Activity

Yufang Xu, P. Mei, Aibin Wu, 2011, Chemical biology & drug design.

A reusable bifunctional fluorescent sensor for the detection and removal of silver ions in aqueous solutions

Yufang Xu, X. Qian, Weiping Zhu, 2018, Sensors and Actuators B: Chemical.

A reusable thioether-rich crown-based fluorescent sensor for the detection and removal of mercuric ions.

Yufang Xu, Y. Liu, X. Qian, 2016, Journal of colloid and interface science.

Trace mercury (II) detection and separation in serum and water samples using a reusable bifunctional fluorescent sensor.

Tao Chen, X. Qian, Chunsheng He, 2009, Analytica chimica acta.

Hydrazine detection in the gas state and aqueous solution based on the Gabriel mechanism and its imaging in living cells.

Yufang Xu, X. Qian, Zhixing Peng, 2014, Chemical communications.

Micro/nano flow chemistry by Beyond Limits Manufacturing

Yunpeng Bai, Yangyang Yang, Weiping Zhu, 2023, Chinese Chemical Letters.

Zinc triflate-mediated cyclopropanation of oxindoles with vinyl diphenyl sulfonium triflate: a mild reaction with broad functional group compatibility

Ke En, Yufang Xu, Xuhong Qian, 2017 .

Modulating the selectivity by switching sensing media: a bifunctional chemosensor selectivity for Cd2+ and Pb2+ in different aqueous solutions

Yufang Xu, X. Qian, Weiping Zhu, 2012 .

pH-Sensitive and folate receptor-targeting gold nanorods for fluorescence/photoacoustic imaging and photothermal therapy of tumor

X. Qian, Weiping Zhu, Yao Tang, 2017 .

A DPA-based highly selective and sensitive fluorescent probe for mercuric ions and its imaging in living cells.

Chusen Huang, X. Qian, Weiping Zhu, 2016, Dalton transactions.

Novel naphthalimide hydroperoxide photonucleases: the role of thiocyclic-fused area and the difference in spectra, photochemistry and photobiological activity.

Yufang Xu, X. Qian, Wei Yao, 2003, Bioorganic & medicinal chemistry.

Selective and sensitive detection and quantification of arylamine N-acetyltransferase 2 by a ratiometric fluorescence probe.

X. Qian, Weiping Zhu, Lei Cui, 2010, Chemical communications.

Reactive fluorescent dye functionalized cotton fabric as a “Magic Cloth” for selective sensing and reversible separation of Cd2+ in water

Yuanyuan Luo, X. Qian, Weiping Zhu, 2015 .

An ESIPT-based fluorescent probe for sensitive detection of hydrazine in aqueous solution.

Yufang Xu, X. Qian, Rui Wang, 2015, Organic & biomolecular chemistry.