Cho Tang

Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases.

G. Mcmahon, L. Sun, C. Tang, 1998, Journal of medicinal chemistry.

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.

A. Ullrich, G. Mcmahon, L. Sun, 1999, Cancer research.

Design, synthesis, and evaluations of substituted 3-[(3- or 4-carboxyethylpyrrol-2-yl)methylidenyl]indolin-2-ones as inhibitors of VEGF, FGF, and PDGF receptor tyrosine kinases.

G. Mcmahon, L. Sun, C. Tang, 1999, Journal of medicinal chemistry.

A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells.

G. Mcmahon, L. Sun, C. Liang, 2001, Cancer research.